Search filters

List of works by Marzia Pennati

Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.

scientific article published on 18 August 2015

Activity of a trinuclear platinum complex in human ovarian cancer cell lines sensitive and resistant to cisplatin: cytotoxicity and induction and gene-specific repair of DNA lesions

scientific article published on May 2001

Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy

scientific article

Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation

scientific article published on 17 February 2009

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

scientific article published on 25 May 2012

Characterization of stress response in human retinal epithelial cells

scientific article published on 4 December 2012

CpG-oligodeoxynucleotides exert remarkable antitumor activity against diffuse malignant peritoneal mesothelioma orthotopic xenografts.

scientific article published on 25 January 2016

Dissecting the role of microRNAs in prostate cancer metastasis: implications for the design of novel therapeutic approaches

scientific article published on 12 March 2016

Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.

scientific article published on 17 December 2013

Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.

scientific article published on 23 August 2013

PF-03446962, a fully-human monoclonal antibody against transforming growth-factor β (TGFβ) receptor ALK1, in pre-treated patients with urothelial cancer: an open label, single-group, phase 2 trial.

scientific article

Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial.

scientific article published on 20 July 2012

Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.

scientific article published in September 2005

RNA interference-mediated validation of survivin and Apollon/BRUCE as new therapeutic targets for cancer therapy.

scientific article published on January 2012

Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression

scientific article published on April 2003

Rational design of shepherdin, a novel anticancer agent.

scientific article

Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma.

scientific article published on 6 August 2010

Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo

scientific article published on 4 February 2004

Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells

scientific article published on January 2004

Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathways

scientific article

Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells

scientific article published on January 2006

Small-Molecule Targeting of Heat Shock Protein 90 Chaperone Function: Rational Identification of a New Anticancer Lead

scientific article published on 01 December 2006

Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)- 1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues.

scientific article published on January 2014

Synthesis and antitumor activity of 3-(2-phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles.

scientific article published on 26 April 2011

Targeting human telomerase by antisense oligonucleotides and ribozymes

scientific article

Targeting survivin in cancer therapy

scientific article

Targeting survivin in cancer therapy: fulfilled promises and open questions

scientific article

Ubiquitin over-expression promotes E6AP autodegradation and reactivation of the p53/MDM2 pathway in HeLa cells.

scientific article published on 9 July 2008

Validation of telomerase and survivin as anticancer therapeutic targets using ribozymes and small-interfering RNAs.

scientific article published on January 2007

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

scientific article

YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation.

scientific article published on 5 June 2014

miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.

scientific article

miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells

scientific article published on 24 December 2013

miR-21: an oncomir on strike in prostate cancer.

scientific article

Paulina is supported by:

About Paulina

Help