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List of works by Raphael Saffroy

Accumulation of an inactive form of p53 protein in cells treated with TNF alpha

scientific article published in May 2002

Acquired KRAS mutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis

scientific article published on 02 April 2010

Analysis of alterations of WFDC1, a new putative tumour suppressor gene, in hepatocellular carcinoma.

scientific article

Analysis of chromosomal instability in pulmonary or liver metastases and matched primary hepatocellular carcinoma after orthotopic liver transplantation

scientific article published in May 2003

Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology

scientific article published on 24 July 2009

Association between a polymorphism in the promoter of a glutamate receptor subunit gene (GRIN2A) and alcoholism

scientific article published on 20 April 2011

Breast metastases from lung cancers with the EGFR mutation

scientific article published on 6 June 2016

Cerebellar high-grade gliomas do not present the same molecular alterations as supratentorial high-grade gliomas and may show histone H3 gene mutations

scientific article published on 01 September 2018

Cetuximab and circadian chronomodulated chemotherapy as salvage treatment for metastatic colorectal cancer (mCRC): safety, efficacy and improved secondary surgical resectability.

scientific article published on 17 April 2010

Clinical significance of circulating anti-p53 antibodies in European patients with hepatocellular carcinoma.

scientific article published on February 1999

Clinical, Imaging, Histopathological and Molecular Characterization of Anaplastic Ganglioglioma.

scientific article published on 18 August 2016

Co expression of SCF and KIT in gastrointestinal stromal tumours (GISTs) suggests an autocrine/paracrine mechanism.

scientific article published on April 2006

Co-occurrence of histone H3 K27M and BRAF V600E mutations in paediatric midline grade I ganglioglioma.

scientific article published on 16 December 2016

Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?

scientific article published on 26 November 2014

Combined Diffuse Astrocytoma and Pleomorphic Xanthoastrocytoma Grade III Sharing IDH1 R132H Mutation

scientific article published on 30 May 2018

Common cancer-associated PIK3CA activating mutations rarely occur in Langerhans cell histiocytosis.

scientific article published in April 2015

Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study.

scientific article published on 13 March 2017

Detection of gammopathy by serum protein electrophoresis for predicting and managing therapy of lymphoproliferative disorder in 911 recipients of liver transplants

scientific article published on 01 September 2001

Effects in Cancer Cells of the Recombinant l-Methionine Gamma-Lyase from Brevibacterium aurantiacum. Encapsulation in Human Erythrocytes for Sustained l-Methionine Elimination

scientific article published on 02 April 2019

Enhancement of 5-Fluorouracil Cytotoxicity by Pyridoxal 5'-Phosphate and Folinic Acid in Tandem

scientific article published on 01 June 2018

Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray

scientific article

Expression of T-cadherin in tumor cells influences invasive potential of human hepatocellular carcinoma

scientific article published on November 2006

Fate and characterization of circulating tumor cells in a NOD/SCID mouse model of human hepatocellular carcinoma.

scientific article published on 20 February 2006

GENE-06. CO-OCCURRENCE OF DOUBLE MUTATION H3F3A/BRAF IN PEDIATRIC GANGLIOGLIOMAS.

scientific article

High expression of both mutant and wild-type alleles of c-kit in gastrointestinal stromal tumors

scientific article published on April 2004

High-throughput somatic mutation profiling in pulmonary sarcomatoid carcinomas using the LungCarta™ Panel: exploring therapeutic targets.

scientific article

Historadiological correlations in high-grade glioma with the histone 3.3 G34R mutation.

scientific article

Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians

scientific article published on 7 February 2017

Importance of the FcgammaRIIa-Arg/His-131 polymorphism in heparin-induced thrombocytopenia diagnosis.

scientific article

Investigation in liver tissues and cell lines of the transcription of 13 genes mapping to the 16q24 region that are frequently deleted in hepatocellular carcinoma

scientific article

KIT overexpression and amplification in gastrointestinal stromal tumors (GISTs).

scientific article published on 13 April 2005

MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer.

scientific article published on 28 October 2009

MET exon 14 mutations as targets in routine molecular analysis of primary sarcomatoid carcinoma of the lung.

scientific article published on 21 March 2017

Microsatellite instability in European hepatocellular carcinoma

scientific article published on 01 January 1999

Microsatellite instability mutator phenotype in hepatocellular carcinoma in non-alcoholic and non-virally infected normal livers.

scientific article

Mitochondrial roles and cytoprotection in chronic liver injury

scientific article

Molecular biology and hepatocellular carcinoma: current status and future prospects

scientific article

Multi-factorial modulation of colorectal carcinoma cells motility - partial coordination by the tetraspanin Co-029/tspan8

scientific article

New perspectives and strategy research biomarkers for hepatocellular carcinoma.

scientific article published on January 2007

Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).

scientific article

Plasma levels of soluble Fc gamma receptors II (sCD32) and III (sCD16) in patients with heparin-induced thrombocytopenia

scientific article published on 01 August 1997

Prospective evaluation of blood concentration of mitochondrial DNA as a marker of toxicity in 157 consecutively recruited untreated or HAART-treated HIV-positive patients.

scientific article

Protective effect against alcohol dependence of the thermolabile variant of MTHFR.

scientific article published on 7 March 2008

Rapid automated simultaneous screening of (G1691A) Factor V, (G20210A) prothrombin, and (C677T) methylenetetrahydrofolate reductase variants by multiplex PCR using fluorescence scanning technology.

scientific article

Rare genetic heterogeneity within single tumor discovered for the first time in colorectal liver metastases after liver resection.

scientific article published on 24 April 2018

Real-time quantification of AFP mRNA to assess hematogenous dissemination after transarterial chemoembolization of hepatocellular carcinoma

scientific article published on 01 August 2003

Real-time quantitation of bcr-abl transcripts in haematological malignancies

scientific article published on 01 October 2000

Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study.

scientific article published in March 2009

Role of Fc gamma RIIA gene polymorphism in human platelet activation by monoclonal antibodies

scientific article published on 01 December 1995

Several clock genes polymorphisms are meaningful risk factors in the development and severity of cannabis addiction

scientific article published on 11 December 2018

Sirolimus plus prednisone for Erdheim-Chester disease: an open-label trial.

scientific article

Tests for heparin-induced thrombocytopenia in primary antiphospholipid syndrome

scientific article published on 01 June 1997

The MTHFR 677C > T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis.

scientific article published on 19 March 2004

Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis

scientific article published on August 2002

Treatment with rituximab, dexamethasone, high-dose cytarabine, and oxaliplatin (R-DHAOx) produces a strong long-term antitumor effect in previously treated patients with follicular non-Hodgkin's lymphoma

scientific article published on 9 December 2009

[Antiplatelet glycoprotein monoclonal antibodies: properties and practical value]

scientific article published on 01 January 1995

c-MET Overexpression as a Poor Predictor of MET Amplifications or Exon 14 Mutations in Lung Sarcomatoid Carcinomas

scientific article published on 24 August 2018

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