List of works - Richard M Siegel

Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture

scientific article

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

scientific article published on 07 May 2020

Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

scientific article

Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations

scientific article published on 14 September 2018

Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: a prospective, open-label, dose-escalation study

scientific article published on March 2012

Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse.

scientific article published on 11 April 2018

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

scientific article published on 23 December 2016

Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

scientific article published on 12 May 2021

Genetically programmed alternative splicing of NEMO mediates an autoinflammatory disease phenotype

scientific article published on 01 March 2022

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

scientific article published on 7 December 2015

Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses

scientific article

Measurement of two caspase activities simultaneously in living cells by a novel dual FRET fluorescent indicator probe

scientific article published in June 2006

Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction

scientific article published on 22 January 2019

Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus

scientific article published on 19 March 2019

Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway

scientific article published on 01 May 2020

Somatic activating mutations in MAP2K1 cause melorheostosis.

scientific article published on 11 April 2018

TRAF6 regulates cell fate decisions by inducing caspase 8-dependent apoptosis and the activation of NF-kappaB.

scientific article published on 25 January 2006

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

scientific article

The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8.

scientific article published on March 2011

To B or not to B: TNF family signaling in lymphocytes

scientific article published on 01 July 2001

Wishing away inflammation? New links between serotonin and TNF signaling

scientific article

List of works by Richard M Siegel

Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome

Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations

Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: a prospective, open-label, dose-escalation study

Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse.

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling

Genetically programmed alternative splicing of NEMO mediates an autoinflammatory disease phenotype

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses

Measurement of two caspase activities simultaneously in living cells by a novel dual FRET fluorescent indicator probe

Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction

Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus

Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway

Somatic activating mutations in MAP2K1 cause melorheostosis.

TRAF6 regulates cell fate decisions by inducing caspase 8-dependent apoptosis and the activation of NF-kappaB.

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8.

To B or not to B: TNF family signaling in lymphocytes

Wishing away inflammation? New links between serotonin and TNF signaling