List of works - Samuel Estrada-Soto

1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies

scientific article published on 05 June 2015

2-(2-Benzyl-oxyphen-yl)-1H-benzimid-azole.

scientific article published on 20 February 2008

4-Meth-oxy-N-[6-methyl-2,3-dihydro-1,3-benzothia-zol-2-yl-idene]benzene-sulfonamide.

scientific article published on 6 December 2007

A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.

scientific article published in March 2010

Acute and sub-acute toxicity methanolic extract from Brickellia cavanillesii in mice

Acute and subacute antidiabetic studies of ENP-9, a new 1,5-diarylpyrazole derivative

scientific article published on 17 May 2018

Analysis of Flavonoids Bioactivity for Cholestatic Liver Disease: Systematic Literature Search and Experimental Approaches

scientific article published on 14 March 2019

Anti-diabetic effect on alloxanized and normoglycemic rats and some pharmacological evaluations of Tournefortia hartwegiana.

scientific article published in October 2005

Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides.

scientific article

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches

scientific article published on 30 March 2011

Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation.

scientific article

Antidiabetic, antidyslipidemic and toxicity profile of ENV-2: A potent pyrazole derivative against diabetes and related diseases.

scientific article published on 17 March 2017

Antidiabetic, antihyperlipidemic and anti-inflammatory effects of tilianin in streptozotocin-nicotinamide diabetic rats.

scientific article published on 26 July 2016

Antihypertensive and vasorelaxant activities of Laelia autumnalis are mainly through calcium channel blockade.

scientific article published on 26 April 2008

Antihypertensive and vasorelaxant effects of dihydrospinochalcone-A isolated from Lonchocarpus xuul Lundell by NO production: computational and ex vivo approaches.

scientific article published on 20 July 2013

Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening.

scientific article published on 27 March 2009

Anxiolytic-like effects and toxicological studies of Brickellia cavanillesii (Cass.) A. Gray in experimental mice models

scientific article published on 2 July 2016

Anxiolytic-like effects of Brickellia cavanillesii and their bioactive compounds nicotiflorin and acacetin in experimental models in mice

Biopharmaceutical Characterization and Bioavailability Study of a Tetrazole Analog of Clofibric Acid in Rat.

scientific article published on 14 February 2017

Chemical constituents of the hemiparasitic plant Phoradendron brachystachyum DC Nutt (Viscaceae)

scientific article published on 23 February 2012

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice.

scientific article published on 28 December 2017

Cochlospermum vitifolium induces vasorelaxant and antihypertensive effects mainly by activation of NO/cGMP signaling pathway.

scientific article published on 27 May 2010

Crystal structure of 4-methyl-7-prop-oxy-2H-chromen-2-one

scientific article published on 31 October 2014

Depressant effects of Agastache mexicana methanol extract and one of major metabolites tilianin

scientific article published on 01 March 2015

Design, Synthesis and in Combo Antidiabetic Bioevaluation of Multitarget Phenylpropanoic Acids.

scientific article published on 6 February 2018

Design, microwave-assisted synthesis, and spasmolytic activity of 2-(alkyloxyaryl)-1H-benzimidazole derivatives as constrained stilbene bioisosteres

scientific article published on 19 June 2006

Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.

scientific article published on 30 July 2010

Differential role of cyclooxygenase-1 and -2 on renal vasoconstriction to α₁-adrenoceptor stimulation in normotensive and hypertensive rats

scientific article published on 06 September 2013

Discovery of 2-(3,4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl)acetamide: A selective σ1 receptor ligand with antinociceptive effect

scientific article published on 14 March 2016

Discovery of new dual PPARγ-GPR40 agonists with robust antidiabetic activity: Design, synthesis and in combo drug evaluation

scientific article published on 22 March 2017

Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual PPAR α/γ modulator with antidiabetic effect: in vitro, in silico and in vivo approaches.

scientific article published on 21 March 2013

Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent

scientific article published on 05 April 2013

Dose-dependent antihypertensive determination and toxicological studies of tilianin isolated from Agastache mexicana.

scientific article published on 28 December 2012

Endothelium-independent relaxation of aorta rings by two stilbenoids from the orchids Scaphyglottis livida.

scientific article published on 23 February 2006

Evaluation of the neuroprotective activity of stansin 6, a resin glycoside from Ipomoea stans.

scientific article published on 27 May 2014

Ex Vivo Study of the Vasorelaxant Activity Induced by Phenanthrene Derivatives Isolated from Maxillaria densa

scientific article published on 12 December 2012

Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone

scientific article published on 05 November 2018

Glycolipid ester-type heterodimers from Ipomoea tyrianthina and their pharmacological activity.

scientific article published on 25 June 2009

Hypoglycemic, vasorelaxant and hepatoprotective effects of Cochlospermum vitifolium (Willd.) Sprengel: a potential agent for the treatment of metabolic syndrome.

scientific article published on 15 August 2006

Identification of fatty acid esters and hydrocarbon derivatives from Cyrtocarpa procera Kunth by GC-MS.

scientific article

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives

scientific article published on 03 March 2016

Insights on the vasorelaxant mode of action of malbrancheamide

scientific article published on 03 February 2015

Metronidazole and Secnidazole Carbamates: Synthesis, Antiprotozoal Activity, and Molecular Dynamics Studies

scientific article published on 12 February 2020

Micropropagation and vasorelaxant activity of Laelia autumnalis (Orchidaceae).

scientific article published in January 2010

New phenanthrene derivatives from maxillaria densa(1)

scientific article published on 01 August 1999

New triterpenoids from the orchids Scaphyglottis livida and Nidema boothii.

scientific article

Postprandial glycaemia and inhibition of α-glucosidase activity by aqueous extract from Coriandrum sativum

scientific article published on 16 May 2014

QSAR study on the relaxant agents from some Mexican medicinal plants and synthetic related organic compounds.

scientific article published in August 2007

Relaxant activity of 2-(substituted phenyl)-1H-benzimidazoles on isolated rat aortic rings: design and synthesis of 5-nitro derivatives.

scientific article published on 17 February 2006

Relaxant effects of Artemisia ludoviciana on isolated rat smooth muscle tissues

article

Resin glycosides from Ipomoea tyrianthina and their sedative and vasorelaxant effects

scientific article published on 18 May 2014

Resin glycosides from the roots of Ipomoea tyrianthina and their biological activity

scientific article published on 20 February 2007

Sedative, vasorelaxant, and cytotoxic effects of convolvulin from Ipomoea tyrianthina.

scientific article published on April 2011

Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs.

scientific article published on 12 March 2014

Smooth muscle relaxing flavonoids and terpenoids from Conyza filaginoides

scientific article published on 01 February 1997

Spasmolytic action of Lepechinia caulescens is through calcium channel blockade and NO release.

scientific article published on 19 August 2007

Spasmolytic activity of several extracts obtained from some Mexican medicinal plants.

scientific article published in December 2003

Spasmolytic effect of Mentha pulegium L. involves ionic flux regulation in rat ileum strips.

scientific article published in January 2010

Spasmolytic stilbenoids from Maxillaria densa

scientific article published on 01 December 2004

Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines

scientific article published on 25 May 2007

Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.

scientific article

Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities

scientific article published on 08 January 2014

Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis

scientific article published on 10 March 2015

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition

scientific article published on 16 September 2014

Synthesis, ex vivo and in silico studies of 3-cyano-2-pyridone derivatives with vasorelaxant activity.

scientific article published on 14 October 2013

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model.

scientific article

Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity.

scientific article

Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors

scientific article published on 26 April 2012

Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect

scientific article published on 01 August 2014

Tracheal relaxation of five medicinal plants used in Mexico for the treatment of several diseases.

scientific article published in March 2014

Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.

scientific article

Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta

scientific article published on 21 April 2006

Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies

scientific article published on 29 May 2012

Vasorelaxant and antihypertensive effects of methanolic extract from roots of Laelia anceps are mediated by calcium-channel antagonism.

scientific article published on 30 October 2009

Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker.

scientific article published on September 2010

Vasorelaxant effect of flavonoids through calmodulin inhibition: Ex vivo, in vitro, and in silico approaches

scientific article published on 04 November 2010

Vasorelaxant mode of action of dichloromethane-soluble extract from Agastache mexicana and its main bioactive compounds.

scientific article

alpha-Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: an anti-hyperglycemic agent

scientific article published on 08 July 2006

List of works by Samuel Estrada-Soto

1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies

2-(2-Benzyl-oxyphen-yl)-1H-benzimid-azole.

4-Meth-oxy-N-[6-methyl-2,3-dihydro-1,3-benzothia-zol-2-yl-idene]benzene-sulfonamide.

A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.

Acute and sub-acute toxicity methanolic extract from Brickellia cavanillesii in mice

Acute and subacute antidiabetic studies of ENP-9, a new 1,5-diarylpyrazole derivative

Analysis of Flavonoids Bioactivity for Cholestatic Liver Disease: Systematic Literature Search and Experimental Approaches

Anti-diabetic effect on alloxanized and normoglycemic rats and some pharmacological evaluations of Tournefortia hartwegiana.

Antidiabetic activity of N-(6-substituted-1,3-benzothiazol-2-yl)benzenesulfonamides.

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches

Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation.

Antidiabetic, antidyslipidemic and toxicity profile of ENV-2: A potent pyrazole derivative against diabetes and related diseases.

Antidiabetic, antihyperlipidemic and anti-inflammatory effects of tilianin in streptozotocin-nicotinamide diabetic rats.

Antihypertensive and vasorelaxant activities of Laelia autumnalis are mainly through calcium channel blockade.

Antihypertensive and vasorelaxant effects of dihydrospinochalcone-A isolated from Lonchocarpus xuul Lundell by NO production: computational and ex vivo approaches.

Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening.

Anxiolytic-like effects and toxicological studies of Brickellia cavanillesii (Cass.) A. Gray in experimental mice models

Anxiolytic-like effects of Brickellia cavanillesii and their bioactive compounds nicotiflorin and acacetin in experimental models in mice

Biopharmaceutical Characterization and Bioavailability Study of a Tetrazole Analog of Clofibric Acid in Rat.

Chemical constituents of the hemiparasitic plant Phoradendron brachystachyum DC Nutt (Viscaceae)

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice.

Cochlospermum vitifolium induces vasorelaxant and antihypertensive effects mainly by activation of NO/cGMP signaling pathway.

Crystal structure of 4-methyl-7-prop-oxy-2H-chromen-2-one

Depressant effects of Agastache mexicana methanol extract and one of major metabolites tilianin

Design, Synthesis and in Combo Antidiabetic Bioevaluation of Multitarget Phenylpropanoic Acids.

Design, microwave-assisted synthesis, and spasmolytic activity of 2-(alkyloxyaryl)-1H-benzimidazole derivatives as constrained stilbene bioisosteres

Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.

Differential role of cyclooxygenase-1 and -2 on renal vasoconstriction to α₁-adrenoceptor stimulation in normotensive and hypertensive rats

Discovery of 2-(3,4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl)acetamide: A selective σ1 receptor ligand with antinociceptive effect

Discovery of new dual PPARγ-GPR40 agonists with robust antidiabetic activity: Design, synthesis and in combo drug evaluation

Discovery of thiazolidine-2,4-dione/biphenylcarbonitrile hybrid as dual PPAR α/γ modulator with antidiabetic effect: in vitro, in silico and in vivo approaches.

Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent

Dose-dependent antihypertensive determination and toxicological studies of tilianin isolated from Agastache mexicana.

Endothelium-independent relaxation of aorta rings by two stilbenoids from the orchids Scaphyglottis livida.

Evaluation of the neuroprotective activity of stansin 6, a resin glycoside from Ipomoea stans.

Ex Vivo Study of the Vasorelaxant Activity Induced by Phenanthrene Derivatives Isolated from Maxillaria densa

Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone

Glycolipid ester-type heterodimers from Ipomoea tyrianthina and their pharmacological activity.

Hypoglycemic, vasorelaxant and hepatoprotective effects of Cochlospermum vitifolium (Willd.) Sprengel: a potential agent for the treatment of metabolic syndrome.

Identification of fatty acid esters and hydrocarbon derivatives from Cyrtocarpa procera Kunth by GC-MS.

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives

Insights on the vasorelaxant mode of action of malbrancheamide

Metronidazole and Secnidazole Carbamates: Synthesis, Antiprotozoal Activity, and Molecular Dynamics Studies

Micropropagation and vasorelaxant activity of Laelia autumnalis (Orchidaceae).

New phenanthrene derivatives from maxillaria densa(1)

New triterpenoids from the orchids Scaphyglottis livida and Nidema boothii.

Postprandial glycaemia and inhibition of α-glucosidase activity by aqueous extract from Coriandrum sativum

QSAR study on the relaxant agents from some Mexican medicinal plants and synthetic related organic compounds.

Relaxant activity of 2-(substituted phenyl)-1H-benzimidazoles on isolated rat aortic rings: design and synthesis of 5-nitro derivatives.

Relaxant effects of Artemisia ludoviciana on isolated rat smooth muscle tissues

Resin glycosides from Ipomoea tyrianthina and their sedative and vasorelaxant effects

Resin glycosides from the roots of Ipomoea tyrianthina and their biological activity

Sedative, vasorelaxant, and cytotoxic effects of convolvulin from Ipomoea tyrianthina.

Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs.

Smooth muscle relaxing flavonoids and terpenoids from Conyza filaginoides

Spasmolytic action of Lepechinia caulescens is through calcium channel blockade and NO release.

Spasmolytic activity of several extracts obtained from some Mexican medicinal plants.

Spasmolytic effect of Mentha pulegium L. involves ionic flux regulation in rat ileum strips.

Spasmolytic stilbenoids from Maxillaria densa

Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines

Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.

Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities

Synthesis of nitro(benzo)thiazole acetamides and in vitro antiprotozoal effect against amitochondriate parasites Giardia intestinalis and Trichomonas vaginalis

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition

Synthesis, ex vivo and in silico studies of 3-cyano-2-pyridone derivatives with vasorelaxant activity.

Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model.

Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity.

Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors

Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect

Tracheal relaxation of five medicinal plants used in Mexico for the treatment of several diseases.

Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.

Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta

Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies

Vasorelaxant and antihypertensive effects of methanolic extract from roots of Laelia anceps are mediated by calcium-channel antagonism.

Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker.

Vasorelaxant effect of flavonoids through calmodulin inhibition: Ex vivo, in vitro, and in silico approaches

Vasorelaxant mode of action of dichloromethane-soluble extract from Agastache mexicana and its main bioactive compounds.

alpha-Glucosidase inhibitory activity of the methanolic extract from Tournefortia hartwegiana: an anti-hyperglycemic agent

α-Glucosidase inhibitory activity of extracts from Cordia morelosana