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List of works by Xiang Zhai

Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics.

scientific article published on 16 January 2018

Enzyme Architecture: Amino Acid Side-Chains That Function To Optimize the Basicity of the Active Site Glutamate of Triosephosphate Isomerase

scholarly article by Xiang Zhai et al published 5 July 2018 in Journal of the American Chemical Society

Enzyme Architecture: The Effect of Replacement and Deletion Mutations of Loop 6 on Catalysis by Triosephosphate Isomerase

scientific article

Enzyme activation through the utilization of intrinsic dianion binding energy.

scientific article published on 29 November 2016

Enzyme architecture: on the importance of being in a protein cage

scientific article published on 31 March 2014

Enzyme architecture: remarkably similar transition states for triosephosphate isomerase-catalyzed reactions of the whole substrate and the substrate in pieces

scientific article published on 06 March 2014

Insight into the Therapeutic Selectivity of the Irreversible EGFR Tyrosine Kinase Inhibitor Osimertinib through Enzyme Kinetic Studies

scientific article published on 31 March 2020

Mechanistic Imperatives for Deprotonation of Carbon Catalyzed by Triosephosphate Isomerase: Enzyme-Activation by Phosphite Dianion

scientific article published on April 2014

Reflections on the catalytic power of a TIM-barrel.

scientific article

Role of Loop-Clamping Side Chains in Catalysis by Triosephosphate Isomerase

scientific article

Structural mutations that probe the interactions between the catalytic and dianion activation sites of triosephosphate isomerase

scientific article published on 16 August 2013

Structure-Function Studies of Hydrophobic Residues That Clamp a Basic Glutamate Side Chain during Catalysis by Triosephosphate Isomerase

scientific article published on 05 May 2016

The activating oxydianion binding domain for enzyme-catalyzed proton transfer, hydride transfer, and decarboxylation: specificity and enzyme architecture

scientific article