List of works - Graham S Jackson

A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K.

scientific article

A highly specific blood test for vCJD

scientific article published on January 2014

A reassessment of copper(II) binding in the full-length prion protein

scientific article published on November 2006

A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay

scientific article

A systematic investigation of production of synthetic prions from recombinant prion protein

scientific article

An enzyme-detergent method for effective prion decontamination of surgical steel.

scientific article

Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc

scientific article published on 06 September 2007

Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding.

scientific article published in March 1993

Blood test for variant Creutzfeldt-Jakob disease--reply

scientific article published on 01 August 2014

Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation

scientific article published on 01 August 2006

Conformational properties of beta-PrP.

scientific article published on 15 April 2009

Crystal structure of human prion protein bound to a therapeutic antibody

scientific article

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.

scientific article published on December 2008

Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification

scientific article published on 18 February 2010

Disease-associated prion protein oligomers inhibit the 26S proteasome

scientific article published on April 2007

Domain behavior during the folding of a thermostable phosphoglycerate kinase

scientific article published on 01 December 1996

Efficient dissemination of prions through preferential transmission to nearby cells.

scientific article published on February 2007

Elongated oligomers assemble into mammalian PrP amyloid fibrils

scientific article published on 31 January 2006

Folding kinetics of the human prion protein probed by temperature jump.

scholarly article

Inhibition of proteinase K activity by copper(II) ions.

scientific article published in January 2007

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

scientific article

Location and properties of metal-binding sites on the human prion protein.

scientific article published on 03 July 2001

Mammalian prion proteins.

scientific article

Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS)

scientific article

Molecular biology of prion propagation.

scientific article

Multiple folding pathways for heterologously expressed human prion protein

article

Pharmacological chaperone for the structured domain of human prion protein.

scientific article

Physical, chemical and kinetic factors affecting prion infectivity

scientific article

Population screening for variant Creutzfeldt-Jakob disease using a novel blood test: diagnostic accuracy and feasibility study

scientific article

PrP glycoforms are associated in a strain-specific ratio in native PrPSc

scientific article published on 01 September 2005

PrPSc binding antibodies are potent inhibitors of prion replication in cell lines.

scientific article published on 7 May 2004

Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease

scientific article

Protein conformation significantly influences immune responses to prion protein.

scientific article

Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates

scientific article

Recombinant prion protein does not possess SOD-1 activity.

scientific article published on December 2005

Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations.

scientific article

Spontaneous conformational change within the prion protein--implications for disease pathogenesis?

scientific article published on 01 September 2001

Spontaneous generation of mammalian prions

scientific article

Strain-specific prion-protein conformation determined by metal ions

article

Structural mobility of the human prion protein probed by backbone hydrogen exchange

scientific article published on 01 August 1999

Sucrose reduces the efficiency of protein denaturation by a chaotropic agent

scientific article published on 01 November 1995

Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis

scientific article

The R1441C mutation alters the folding properties of the ROC domain of LRRK2.

scientific article

The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells

article

The energetics and cooperativity of protein folding: a simple experimental analysis based upon the solvation of internal residues.

scientific article published in April 1993

The human prion protein residue 129 polymorphism lies within a cluster of epitopes for T cell recognition.

scientific article published in November 2006

The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease

scientific article

The molecular biology of prion propagation.

scientific article

The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC.

scientific article

The role of the cellular prion protein in the immune system

scientific article

Variant Creutzfeldt-Jakob disease with extremely low lymphoreticular deposition of prion protein

scientific article

List of works by Graham S Jackson

A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K.

A highly specific blood test for vCJD

A reassessment of copper(II) binding in the full-length prion protein

A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay

A systematic investigation of production of synthetic prions from recombinant prion protein

An enzyme-detergent method for effective prion decontamination of surgical steel.

Beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrPSc

Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding.

Blood test for variant Creutzfeldt-Jakob disease--reply

Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation

Conformational properties of beta-PrP.

Crystal structure of human prion protein bound to a therapeutic antibody

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.

Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification

Disease-associated prion protein oligomers inhibit the 26S proteasome

Domain behavior during the folding of a thermostable phosphoglycerate kinase

Efficient dissemination of prions through preferential transmission to nearby cells.

Elongated oligomers assemble into mammalian PrP amyloid fibrils

Folding kinetics of the human prion protein probed by temperature jump.

Inhibition of proteinase K activity by copper(II) ions.

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples.

Location and properties of metal-binding sites on the human prion protein.

Mammalian prion proteins.

Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS)

Molecular biology of prion propagation.

Multiple folding pathways for heterologously expressed human prion protein

Pharmacological chaperone for the structured domain of human prion protein.

Physical, chemical and kinetic factors affecting prion infectivity

Population screening for variant Creutzfeldt-Jakob disease using a novel blood test: diagnostic accuracy and feasibility study

PrP glycoforms are associated in a strain-specific ratio in native PrPSc

PrPSc binding antibodies are potent inhibitors of prion replication in cell lines.

Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease

Protein conformation significantly influences immune responses to prion protein.

Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates

Recombinant prion protein does not possess SOD-1 activity.

Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations.

Spontaneous conformational change within the prion protein--implications for disease pathogenesis?

Spontaneous generation of mammalian prions

Strain-specific prion-protein conformation determined by metal ions

Structural mobility of the human prion protein probed by backbone hydrogen exchange

Sucrose reduces the efficiency of protein denaturation by a chaotropic agent

Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis

The R1441C mutation alters the folding properties of the ROC domain of LRRK2.

The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells

The energetics and cooperativity of protein folding: a simple experimental analysis based upon the solvation of internal residues.

The human prion protein residue 129 polymorphism lies within a cluster of epitopes for T cell recognition.

The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease

The molecular biology of prion propagation.

The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC.

The role of the cellular prion protein in the immune system

Variant Creutzfeldt-Jakob disease with extremely low lymphoreticular deposition of prion protein