Search filters

List of works by Derya R Shimshek

A genetic switch for epilepsy in adult mice.

scientific article published in November 2004

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice

scientific article

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

scientific article published on 14 March 2017

Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.

scientific article

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.

scientific article published on 26 December 2016

Codon-improved Cre recombinase (iCre) expression in the mouse

scientific article (publication date: 2002)

ER-based double iCre fusion protein allows partial recombination in forebrain

scientific article published in November 2002

Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors.

scientific article

Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1

scientific article (publication date: 2012)

Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation.

scientific article published in August 2006

Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging

scientific article

Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging

scientific article

High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain

scientific article (publication date: 2012)

Imaging of cerebrovascular pathology in animal models of Alzheimer's disease

scientific article published on 13 March 2014

Leucine-Rich Repeat Kinase 2 (Lrrk2)-Sensitive Na+/K+ ATPase Activity in Dendritic Cells

scientific article published on 25 January 2017

Leucine-rich repeat kinase 2-sensitive Na+/Ca2+ exchanger activity in dendritic cells.

scientific article published on 21 January 2015

Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice

scientific article published on 17 May 2016

Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner

scientific article published on 01 September 2019

Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice

scientific article (publication date: 2013)

Neuropathology in mice expressing mouse alpha-synuclein

scientific article (publication date: 2011)

Novel one-step immunoassays to quantify α-synuclein: applications for biomarker development and high-throughput screening ⬇️

scientific article published on July 27, 2012

Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.

scientific article published on 25 February 2016

Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition

scientific article published on 14 October 2016

Surfactant secretion in LRRK2 knock-out rats: changes in lamellar body morphology and rate of exocytosis.

scientific article published on 21 January 2014

Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice.

scientific article published in February 2010

Paulina is supported by:

About Paulina

Help