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List of works by Louise E Purton

A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency

scientific article

A novel population of cells expressing both hematopoietic and mesenchymal markers is present in the normal adult bone marrow and is augmented in a murine model of marrow fibrosis

scientific article

A population of nonneuronal GFRα3-expressing cells in the bone marrow resembles nonmyelinating Schwann cells

scientific article published on 14 July 2019

A stressed niche not Wnted

scientific article published on 01 September 2011

ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells.

scientific article published on 11 December 2012

Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.

scientific article published on 30 June 2016

All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia

scientific article published on 10 December 2019

All-trans retinoic acid in non-promyelocytic acute myeloid leukemia: driver lesion dependent effects on leukemic stem cells

scientific article published on 08 September 2020

An oxysterol-binding protein family identified in the mouse.

scientific article

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr ⬇️

scientific article published on February 2016

Cell division and hematopoietic stem cells: not always exhausting

scientific article published on 7 July 2005

Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure.

scientific article

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells

scientific article published on 01 February 2005

Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies.

scientific article

Defining the hematopoietic stem cell niche: the chicken and the egg conundrum.

scientific article published on June 2011

Effects of chemotherapy agents used to treat pediatric acute lymphoblastic leukemia patients on bone parameters and longitudinal growth of juvenile mice

scientific article published on 10 February 2020

Effects of the bone marrow microenvironment on hematopoietic malignancy.

scientific article published on 09 June 2010

EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.

scientific article

Erythroid-extrinsic regulation of normal erythropoiesis by retinoic acid receptors.

scientific article

Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment

scientific article published on 18 March 2011

Generation and analysis of Siah2 mutant mice.

scientific article

Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

scientific article published on 01 February 2007

Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.

scientific article

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

scientific article published on 07 May 2019

Identification of the molecular requirements for an RAR alpha-mediated cell cycle arrest during granulocytic differentiation.

scientific article published on 23 October 2003

Identifying epigenetic targets in osteosarcoma and differentiating osteoblasts

article published in 2010

Imaging methods used to study mouse and human HSC niches: Current and emerging technologies

scientific article published on 25 April 2018

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

scientific article published on 04 April 2016

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.

scientific article published on 6 December 2017

Limiting factors in murine hematopoietic stem cell assays.

scientific article published on September 2007

Mesenchymal lineage cells and their importance in B lymphocyte niches

scientific article published on 25 November 2017

MicroRNA miR-125a controls hematopoietic stem cell number

scientific article

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

scientific article published on 26 February 2013

Modeling human RNA spliceosome mutations in the mouse: not all mice were created equal

scientific article published on 06 November 2018

Monocytes are the likely candidate 'stromal' cell in G-CSF-mobilized peripheral blood.

scientific article published in May 1998

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias

scientific article published on 25 February 2008

Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells.

scientific article

Myelosuppressive therapies significantly increase pro-inflammatory cytokines and directly cause bone loss

scientific article published on 01 May 2015

Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells

scientific article published on 16 January 2005

Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways

scholarly article

Osteoclasts eat stem cells out of house and home

scientific article published on 01 June 2006

Osteopenia in Siah1a mutant mice.

scientific article

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

scientific article published on 4 April 2016

PDGF-AB and azacitidine induced reprogramming of somatic cells into tissue regenerative multipotent stem cells

scientific article published in September 2015

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

scientific article

Protagonist or antagonist? The complex roles of retinoids in the regulation of hematopoietic stem cells and their specification from pluripotent stem cells

scientific article published on 04 July 2018

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation

scientific article

RARγ is a negative regulator of osteoclastogenesis

scientific article published on 20 March 2015

Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment

scientific article published on June 2007

Retinoic Acid Receptor γ Activity in Mesenchymal Stem Cells Regulates Endochondral Bone, Angiogenesis, and B Lymphopoiesis

scientific article published on 08 August 2018

Retinoic Acid Receptor γ Regulates B and T Lymphopoiesis via Nestin-Expressing Cells in the Bone Marrow and Thymic Microenvironments.

scientific article published on 3 February 2016

Retinoic acid receptor signalling directly regulates osteoblast and adipocyte differentiation from mesenchymal progenitor cells.

scientific article published on 10 December 2016

Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation.

scientific article

Src family kinases and their role in hematological malignancies

scientific article

Srsf2P95Hinitiates myeloid bias and myelodysplastic/myeloproliferative syndrome (MDS/MPN) from hemopoietic stem cells

article

Sugar Rush: Supercharging Blood Cell Specification via the Inflammasome

scientific article published on 01 October 2020

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

scientific article

Taking HSCs down a Notch in leukemia.

scientific article published in June 2011

The DNA helicase recql4 is required for normal osteoblast expansion and osteosarcoma formation

scientific article

The Role of p202 in Regulating Hematopoietic Cell Proliferation and Differentiation

scientific article published on 01 January 2008

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

scientific article

The granulocyte-colony stimulating factor receptor (G-CSFR) interacts with retinoic acid receptors (RARs) in the regulation of myeloid differentiation

scientific journal article

The haematopoietic stem cell niche: a new player in cardiovascular disease?

scientific article published on 01 February 2019

The hematopoietic stem cell niche

scientific article published on 9 July 2010

The role of vitamin A and retinoic acid receptor signaling in post-natal maintenance of bone.

scientific article published on October 2015

Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

scientific article

What is the true nature of the osteoblastic hematopoietic stem cell niche?

scientific article published on August 2009

Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma

scientific article published on 5 January 2015

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

scientific article published in Scientific Reports

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