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List of works by Lisa G Horvath

A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis.

scientific article

A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer.

scientific article published on 25 July 2017

A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers.

scientific article

A prospective multicentre phase III validation study of AZGP1 as a biomarker in localized prostate cancer.

scientific article published on 9 May 2017

Aberrant Neuropeptide Y and Macrophage Inhibitory Cytokine-1 Expression Are Early Events in Prostate Cancer Development and Are Associated with Poor Prognosis

article

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer.

scientific article published on 7 November 2017

Adjuvant chemotherapy in elderly patients with pancreatic cancer.

scientific article

Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer.

scientific article

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

scientific article published on 04 December 2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scientific article published on 11 June 2018

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Bone disease in prostate cancer.

scientific article published in March 2010

CMRF-56(+) blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses

scientific article published on 05 May 2016

Cardiac metastasis in Merkel cell carcinoma.

scientific article published on 27 January 2014

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

scientific article published on 20 March 2019

Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer

scientific article

Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer.

scientific article

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

scientific article published on 01 February 2019

Decision making in older patients with advanced cancer: does doctor know best?

scientific article published on 01 January 2012

Discovering cancer vulnerabilities using high-throughput micro-RNA screening

scientific article published on 16 November 2017

EGFR-Co-Mutated Advanced NSCLC and Response to EGFR Tyrosine Kinase Inhibitors.

scientific article

ERG induces taxane resistance in castration-resistant prostate cancer

scientific article

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

scientific article

Enduring epigenetic landmarks define the cancer microenvironment

scientific article published on 12 April 2018

Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers.

scientific article

Exercise-based rehabilitation for cancer survivors with chemotherapy-induced peripheral neuropathy

scientific article published on 12 February 2019

Expression of Androgen Receptor Splice Variant 7 or 9 in Whole Blood Does Not Predict Response to Androgen-Axis-targeting Agents in Metastatic Castration-resistant Prostate Cancer.

scientific article published on 2 February 2018

Expression of E6AP and PML predicts for prostate cancer progression and cancer-specific death

scientific article published on 17 September 2014

Expression of phosphorylated-mTOR during the development of prostate cancer.

scientific article published on 07 July 2014

Expression of the zinc transporter ZnT4 is decreased in the progression from early prostate disease to invasive prostate cancer.

scientific article

Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer

scientific article published on August 2004

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer

scientific article published on 15 January 2019

Extraprostatic extension (EPE) of prostatic carcinoma: is its proximity to the surgical margin or Gleason score important?

scientific article published on 19 August 2014

FAK signaling in human cancer as a target for therapeutics

scientific article

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Frequent loss of estrogen receptor-beta expression in prostate cancer.

scientific article published in July 2001

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

scientific article

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

scientific article

High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy.

scientific article published on 12 October 2011

INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival.

scientific article published on 4 October 2014

Identification of candidate biomarkers of therapeutic response to docetaxel by proteomic profiling.

scientific article published on 22 September 2009

Identification of novel response and predictive biomarkers to Hsp90 inhibitors through mass spectrometry-based proteomic profiling of patient-derived prostate tumor explants

scientific article published on 9 April 2018

Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse.

scientific article

Implementing Intensity-modulated Radiotherapy with Simultaneous Integrated Boost for Anal Cancer: 3 Year Outcomes at Two Sydney Institutions

scientific article published on 14 September 2015

Loss of AZGP1 as a Superior Predictor of Relapse in Margin-Positive Localized Prostate Cancer

scientific article published on 30 July 2016

Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression.

scientific article published in May 2004

Low AZGP1 expression predicts for recurrence in margin-positive, localized prostate cancer

scientific article published on 22 March 2011

Lower levels of nuclear beta-catenin predict for a poorer prognosis in localized prostate cancer.

scientific article

Lymphatic vessel density and lymph node metastasis in prostate cancer

scientific article published on 01 November 2005

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

scientific article

Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer

scientific article published on 21 August 2014

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer.

scientific article

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

scientific article published on 05 October 2016

Neurophysiological and clinical outcomes in chemotherapy-induced neuropathy in cancer.

scientific article

Optimal clinical assessment strategies for chemotherapy-induced peripheral neuropathy (CIPN): a systematic review and Delphi survey.

scientific article published on 7 June 2017

Outcomes of patients with non-melanoma solid tumours receiving self-funded pembrolizumab at Chris O'Brien Lifehouse

scientific article

PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma.

scientific article

Pathways of chemotherapy resistance in castration-resistant prostate cancer.

scientific article published on 04 July 2011

Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma.

scientific article published on April 2013

Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer.

scientific article published on 9 March 2017

Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancer

scientific article published on 5 November 2013

Phosphorylated Akt expression is a prognostic marker in early-stage non-small cell lung cancer

scientific article published on 21 November 2013

Posterior reversible encephalopathy syndrome following chemotherapy with oxaliplatin and a fluoropyrimidine: a case report and literature review.

scientific article published on June 2012

Predictive value of the 2014 International Society of Urological Pathology grading system for prostate cancer in patients undergoing radical prostatectomy with long-term follow-up

scientific article

Prognostic Utility of a Whole-blood Androgen Receptor-based Gene Signature in Metastatic Castration-resistant Prostate Cancer

scientific article published on 15 May 2019

Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens.

scientific article published on August 2011

Proteins from the Wnt pathway are involved in the pathogenesis and progression of mammary phyllodes tumours

scientific article published on 01 November 2009

Remarkable temporal stability of high-abundance human plasma proteins assessed by targeted mass spectrometry.

scientific article published on 8 November 2012

Reporting clinical trial information: colorectal cancer trials at Sydney Cancer Centre

scientific article published on 01 April 2012

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

scientific article published on 3 June 2016

Results of a Prospective Phase 2 Pilot Trial of 177Lu–PSMA-617 Therapy for Metastatic Castration-Resistant Prostate Cancer Including Imaging Predictors of Treatment Response and Patterns of Progression

scientific article published in February 2019

Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target.

scientific article published on 6 September 2016

Second opinions in oncology: the experiences of patients attending the Sydney Cancer Centre.

scientific article

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials

scientific article

Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer

scientific article

Serum Free Methylated Glutathione S-transferase 1 DNA Levels, Survival, and Response to Docetaxel in Metastatic, Castration-resistant Prostate Cancer: Post Hoc Analyses of Data from a Phase 3 Trial

scientific article published on 19 November 2018

Stage migration in localized prostate cancer has no effect on the post-radical prostatectomy Kattan nomogram.

scientific article

Statins - No more cream for cancer

scientific article published on 16 March 2019

Supporting treatment decision making in advanced cancer: a randomized trial of a decision aid for patients with advanced colorectal cancer considering chemotherapy

scientific article published on 11 April 2011

Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse.

scientific article

Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization.

scientific article published on 7 June 2013

The GOFURTGO Study: AGITG Phase II Study of fixed dose rate gemcitabine–oxaliplatin integrated with concomitant 5FU and 3-D conformal radiotherapy for the treatment of localised pancreatic cancer ⬇️

scientific article published on January 3, 2012

The evolution of chemotherapy for the treatment of prostate cancer.

scientific article published on 16 July 2017

Unusual presentations of germ cell tumors. Case 2. Seminoma of the conus medullaris

scientific article published on 01 February 2001

What’s new in non-small cell lung cancer for pathologists the importance of accurate subtyping, EGFR mutations and ALK rearrangements ⬇️

scientific article published on February 1, 2011

Zinc-alpha2-glycoprotein Expression as a Predictor of Metastatic Prostate Cancer Following Radical Prostatectomy

article

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