List of works - Derek Y Chiang

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

scientific article published on 22 February 2009

A probabilistic framework for aligning paired-end RNA-seq data

scientific article

A robust method for transcript quantification with RNA-seq data.

scientific article

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression

scientific article

Cancer gene discovery in hepatocellular carcinoma

scientific article

DiffSplice: the genome-wide detection of differential splicing events with RNA-seq.

scientific article published on 15 November 2012

FDM: a graph-based statistical method to detect differential transcription using RNA-seq data

scientific article

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

scientific article published on August 2008

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

scientific article

Genomics and signaling pathways in hepatocellular carcinoma.

scientific article published on February 2007

High-resolution mapping of copy-number alterations with massively parallel sequencing

scientific article

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

scientific article published on 19 October 2015

IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.

scientific article

ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells

scientific article published on 28 December 2020

Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation.

scientific article

MapSplice: accurate mapping of RNA-seq reads for splice junction discovery.

scientific article

Mapping duplicated sequences

scientific article published on 01 November 2009

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

scientific article published on 13 February 2011

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas ⬇️

scientific article published on July 23, 2012

Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma.

scientific article published on May 2014

Pathogenesis of hepatocellular carcinoma and molecular therapies.

scientific article published on May 2009

Pivotal role of mTOR signaling in hepatocellular carcinoma

scientific article published on 20 August 2008

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.

scientific article published on 13 April 2015

Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma.

scientific article

The landscape of somatic copy-number alteration across human cancers

scientific article

Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss.

scientific article published on February 2015

iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data

scientific article

List of works by Derek Y Chiang

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

A probabilistic framework for aligning paired-end RNA-seq data

A robust method for transcript quantification with RNA-seq data.

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression

Cancer gene discovery in hepatocellular carcinoma

DiffSplice: the genome-wide detection of differential splicing events with RNA-seq.

FDM: a graph-based statistical method to detect differential transcription using RNA-seq data

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

Genomics and signaling pathways in hepatocellular carcinoma.

High-resolution mapping of copy-number alterations with massively parallel sequencing

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.

ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells

Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation.

MapSplice: accurate mapping of RNA-seq reads for splice junction discovery.

Mapping duplicated sequences

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas ⬇️

Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma.

Pathogenesis of hepatocellular carcinoma and molecular therapies.

Pivotal role of mTOR signaling in hepatocellular carcinoma

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.

Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma.

The landscape of somatic copy-number alteration across human cancers

Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss.

iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data