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List of works by Fekade Bruck Sime

A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration

scientific article published on 20 December 2019

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminaemia receiving continuous venovenous haemodiafiltration

scientific article published on 19 July 2018

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

scientific article published on 16 November 2019

Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies

scientific article

Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy

scientific article

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

scientific article published on 16 January 2014

Antibiotic Dosing In Critically Ill Patients Receiving Renal Replacement Therapy

scientific article published on 29 January 2016

Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization

scientific article published on 25 June 2015

Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial

scientific article published on 7 May 2015

Cerebrospinal fluid penetration of ceftolozane/tazobactam in critically ill patients with an indwelling external ventricular drain

scientific article published on 19 October 2020

Challenges in Antifungal Therapy in Diabetes Mellitus

scientific article published on 06 September 2020

Characterization of Effects of Renal Replacement Therapy Modalities and Settings on Pharmacokinetics of Meropenem and Vaborbactam

scientific article published on 24 September 2018

Development of Population and Bayesian Models for Applied Use in Patients Receiving Cefepime

scientific article published on 05 March 2020

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli.

scientific article published on 3 January 2018

Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review

scientific article

Dosing antibiotic prophylaxis during cardiopulmonary bypass-a higher level of complexity? A structured review

scientific article

Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing <i>Escherichia coli</i> in South Asia

scientific article published in 2021

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

scientific article

How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients

scientific article published on 01 December 2018

Individualising Therapy to Minimize Bacterial Multidrug Resistance

scientific article published in April 2018

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: A systematic review

scientific article published on 23 November 2018

Multidrug-resistant Acinetobacter baumannii infections: Current evidence on treatment options and the role of pharmacokinetics/pharmacodynamics in dose optimisation

article

Optimization of dosing regimens and dosing in special populations.

scientific article published on 13 May 2015

Optimizing dosing of antibiotics in critically ill patients

scientific article published on 18 September 2015

Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against <i>Escherichia coli</i> clinical isolates

scientific article published in 2022

Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase (ESBL)-producing versus non-ESBL-producing Escherichia coli in a hollow-fibre infection model

scientific article published in 2022

Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing <i>Escherichia coli</i> clinical isolates in a hollow-fibre infection model

scientific article published in 2022

Pharmacodynamics of Aerosolized Fosfomycin and Amikacin against Resistant Clinical Isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a Hollow-Fiber Infection Model: Experimental Basis for Combination Therapy

scientific article published on 24 October 2016

Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection Model

scientific article published in 2022

Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients.

scientific article published on 25 May 2018

Population Pharmacokinetics of Unbound Ceftolozane and Tazobactam in Critically Ill Patients without Renal Dysfunction

scientific article published on 23 September 2019

Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients

scientific article published on 06 June 2019

Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies

scientific article published on 24 April 2014

Solid nanoparticles for oral antimicrobial drug delivery: a review

scientific article published on 14 January 2019

The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A systematic review and meta-analysis

scientific article published on 30 September 2019

Using Population Pharmacokinetic Modeling and Monte Carlo Simulations To Determine whether Standard Doses of Piperacillin in Piperacillin-Tazobactam Regimens Are Adequate for the Management of Febrile Neutropenia

scientific article published on 14 August 2017

Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?

scientific article published on 01 June 2019

What Antibiotic Exposures Are Required to Suppress the Emergence of Resistance for Gram-Negative Bacteria? A Systematic Review

scientific article published on 01 November 2019

β-lactam antibiotic versus combined β-lactam antibiotics and single daily dosing regimens of aminoglycosides for treating serious infections: A meta-analysis

scientific article published on 05 November 2019

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