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List of works by Paul F Pilch

A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization.

scientific article published on 03 December 2007

Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes

scientific article

Alteration in the expression of GLUT-1 and GLUT-4 protein and messenger RNA levels in denervated rat muscles

scientific article published on 01 October 1992

An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

scientific article published on 15 December 2020

Autophosphorylation within insulin receptor .beta.-subunits can occur as an intramolecular process ⬇️

scientific article published on August 6, 1991

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

scientific article published in November 1997

C2C12 myocytes lack an insulin-responsive vesicular compartment despite dexamethasone-induced GLUT4 expression.

scientific article published in September 2002

Caveolae and lipid trafficking in adipocytes

scientific article

Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells.

scientific article

Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling

scientific article published on 11 July 2013

Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity.

scientific article

Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity

scientific article

Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance.

scientific article

Cavin1; a regulator of lung function and macrophage phenotype

scientific article

Cellular spelunking: exploring adipocyte caveolae

scientific article published on 11 May 2007

Characterization and solubilization of the cytochalasin B binding component from human placental microsomes

scientific article published on 01 October 1984

Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion

scientific article (publication date: 2012)

Chromatographic resolution of insulin receptor from insulin-sensitive D-glucose transporter of adipocyte plasma membranes

scientific article published on 01 January 1981

Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells

scientific article

Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1

scientific article

Coated vesicles participate in the receptor-mediated endocytosis of insulin

scientific article

Conformational changes of the insulin receptor upon insulin binding and activation as monitored by fluorescence spectroscopy.

scientific article published on March 1997

Coordinate modulation of D-glucose transport activity and bilayer fluidity in plasma membranes derived from control and insulin-treated adipocytes.

scientific article

Critical proliferation-independent window for basic fibroblast growth factor repression of myogenesis via the p42/p44 MAPK signaling pathway.

scientific article published on 25 January 2001

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance

scientific article

Differential regulation of glucose transporter 1 and 2 mRNA expression by epidermal growth factor and transforming growth factor-beta in rat hepatocytes

scientific article published on 01 November 1992

Dissociation of insulin receptor expression and signaling from caveolin-1 expression.

scientific article published on 7 February 2005

Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin.

scientific article published on 20 October 2005

Dynamics of protein-tyrosine phosphatases in rat adipocytes

scientific journal article

Dynamics of signaling during insulin-stimulated endocytosis of its receptor in adipocytes

scientific article published on 01 January 1995

Effect of Thyroid Status on Insulin Action in Rat Adipocytes and Skeletal Muscle ⬇️

scientific article published on September 1, 1980

Expression and compartmentalization of caveolin in adipose cells: coordinate regulation with and structural segregation from GLUT4.

scientific article

Expression of an insulin-regulatable glucose carrier in muscle and fat endothelial cells

scientific article published in Nature

Expression of the glucose transporter isoform GLUT 4 is insufficient to confer insulin-regulatable hexose uptake to cultured muscle cells

scientific article published on March 1, 1992

Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes ⬇️

scientific article published on May 17, 2011

Fluorine-containing analogs of intermediates in the shikimate pathway ⬇️

scientific article (publication date: 30 November 1976)

Glucose transporters: what's in a name?

scientific article published on January 1990

Glut4 is targeted to specific vesicles in adipocytes of transgenic mice overexpressing Glut4 selectively in adipose tissue

scientific article published on 01 May 1996

Glut4 storage vesicles without Glut4: transcriptional regulation of insulin-dependent vesicular traffic

scientific article published on August 2004

Hexose transport in adipocytes: stimulation by insulin in the absence of intact receptor

scientific article published on 01 January 1980

Hormone binding alters the conformation of the insulin receptor

scientific article published on 01 December 1980

Identification and characterization of an exercise-sensitive pool of glucose transporters in skeletal muscle

scientific article published on 01 November 1995

Identification of a protein kinase as an intrinsic component of rat liver coated vesicles.

scientific article published on September 1984

Identification of the glucagon receptor in rat liver membranes by photoaffinity crosslinking.

scientific article

Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling

scientific journal article

Induction of Akt-2 correlates with differentiation in Sol8 muscle cells

scientific article published on 01 October 1998

Insulin Increases the Association of Akt-2 with Glut4-containing Vesicles ⬇️

scientific article published on March 27, 1998

Insulin secretion and action and diabetes mellitus

scientific article published on 01 January 1992

Insulin stimulates the tyrosine phosphorylation of a 165 kDa protein that is associated with microsomal membranes of rat adipocytes.

scientific article

Insulin-dependent phosphorylation of a 70-kDa protein in light microsomes from rat adipocytes.

scientific article published on October 2000

Insulin-like growth factor I binding and receptor kinase in red and white muscle

scientific article published on 01 July 1988

Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons ⬇️

scientific article published on May 10, 1979

Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability.

scientific article published on 12 January 2018

Intrinsic kinase activity of the insulin receptor.

scientific article published on January 1990

Isolation of GLUT4 storage vesicles.

scientific article published in April 2006

Isolation of a proteolytically derived domain of the insulin receptor containing the major site of cross-linking/binding

scientific article published on 01 April 1989

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

scientific article

Modification of the insulin receptor by diethyl pyrocarbonate: effect on insulin binding and action

scientific article published on 01 October 1982

Muscular dystrophy in PTFR/cavin-1 null mice

scientific article published on 9 March 2017

PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges

scientific article

Pleiotropic effects of cavin-1 deficiency on lipid metabolism

scientific article published on 07 February 2014

Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling

scientific article

Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes

scientific article published in Journal of Biological Chemistry

Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPalpha.

scientific article published on March 1999

Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues

scientific article

Regulation of glycogen concentration and glycogen synthase activity in skeletal muscle of insulin-resistant rats.

scientific article published on 2 May 2007

Role of PPAR gamma in regulating adipocyte differentiation and insulin-responsive glucose uptake.

scientific article published on November 1999

Role of caveolin-1 and cholesterol in transmembrane fatty acid movement.

scientific article published on March 2006

Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes

scientific journal article

Separation and characterization of three insulin receptor species that differ in subunit composition

scientific article published on 01 July 1988

Separation of IRS-1 and PI3-kinase from GLUT4 vesicles in rat skeletal muscle

scientific article published on 01 May 1998

Separation of endocytic from exocytic coated vesicles using a novel cholinesterase mediated density shift technique

scientific article published on 01 February 1986

Sortilin is a major protein component of Glut4-containing vesicles

scientific article

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

scientific article published in Nature

Structural features of the insulin effector system: relation to hexose transport activation

scientific article published on 01 January 1980

The Formin family protein, formin homolog overexpressed in spleen, interacts with the insulin-responsive aminopeptidase and profilin IIa

scientific article (publication date: July 2003)

The Sugar Is sIRVed: Sorting Glut4 and Its Fellow Travelers ⬇️

scientific article published on March 15, 2011

The beta subunit of the insulin receptor is an insulin-activated protein kinase

scientific article published on 01 February 1983

The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

scientific article

The expression and regulation of STATs during 3T3-L1 adipocyte differentiation.

scientific article published on May 1996

The insulin-like growth factor II/mannose 6-phosphate receptor utilizes the same membrane compartments as GLUT4 for insulin-dependent trafficking to and from the rat adipocyte cell surface

scientific article published on 01 September 1996

The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation

scientific article

The ligand binding subunit of the insulin-like growth factor 1 receptor has properties of a peripheral membrane protein

scientific article published on 01 April 1986

The mass action hypothesis: formation of Glut4 storage vesicles, a tissue-specific, regulated exocytic compartment.

scientific article published on January 2008

Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

scientific article published on January 1997

UCP-3 expression in skeletal muscle: effects of exercise, hypoxia, and AMP-activated protein kinase.

scientific article published in September 2000

Unique cytochalasin B binding characteristics of the hepatic glucose carrier

scientific article published on 01 April 1983

Vanadate treatment of streptozotocin diabetic rats restores expression of the insulin-responsive glucose transporter in skeletal muscle

scientific article published on 01 May 1990

gp160, a tissue-specific marker for insulin-activated glucose transport

scientific article published on August 1994

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