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List of works by Marcus O Butler

A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium

scientific article published on 14 August 2018

A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1+ TCRs.

scientific article

A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.

scientific article

A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles

scientific article

An interim report on the investigator-initiated phase 2 study of pembrolizumab immunological response evaluation (INSPIRE)

scientific article published on 13 March 2019

Arginine methylation of FOXP3 is crucial for the suppressive function of regulatory T cells

scientific article published on 11 October 2018

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma.

scientific article published on 16 November 2017

BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models

scientific article

CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells

scientific article published on 31 March 2016

CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.

scientific article published on 31 December 2015

CapTCR-seq: hybrid capture for T-cell receptor repertoire profiling

scientific article published on 01 December 2018

Chaperones of the class I peptide-loading complex facilitate the constitutive presentation of endogenous antigens on HLA-DP84GGPM87

scientific article published on 08 May 2019

Correction: Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs

scientific article published in May 2017

DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models.

scientific article published on 15 May 2018

Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials

scientific article published on 07 December 2018

Dose-Ranging and Cohort-Expansion Study of Monalizumab (IPH2201) in Patients with Advanced Gynecologic Malignancies: A Trial of the Canadian Cancer Trials Group (CCTG): IND221

scientific article published on 15 July 2019

Establishment of Antitumor Memory in Humans Using in Vitro–Educated CD8 + T Cells ⬇️

scientific article published on April 27, 2011

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

scientific article published on 01 December 2019

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

scientific article

Genetic ablation of HLA class I, class II, and the T cell receptor enables allogeneic T cells to be used for adoptive T cell therapy

scientific article published on 22 April 2020

Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).

scientific article

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

scientific article published on 10 May 2017

Human cell-based artificial antigen-presenting cells for cancer immunotherapy

scientific article

Hyperprogressive disease in early-phase immunotherapy trials: Clinical predictors and association with immune-related toxicities

scientific article published on 15 February 2019

IL-21 Can Supplement Suboptimal Lck-Independent MAPK Activation in a STAT-3–Dependent Manner in Human CD8+ T Cells ⬇️

scientific article published on January 11, 2012

Impact of somatic molecular profiling on clinical trial outcomes in rare epithelial gynecologic cancer patients

scientific article published on 18 February 2019

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

scientific article published on 21 December 2016

Malignant Bowel Obstruction in Advanced Gynecologic Cancers: An Updated Review from a Multidisciplinary Perspective.

scientific article published on 17 May 2018

Mechanisms underlying the lack of endogenous processing and CLIP-mediated binding of the invariant chain by HLA-DP84Gly

scientific article published on 19 March 2018

Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors

scientific article

Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy

scientific article

PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma

scientific article published on 07 December 2020

Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago and California Consortia (NCI9322/PHL86)

scientific article published on 28 January 2020

Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2

scientific article published on 11 February 2019

Randomized Phase II Trial and Tumor Mutational Spectrum Analysis from Cabozantinib versus Chemotherapy in Metastatic Uveal Melanoma (Alliance A091201)

scientific article published on 26 September 2019

Specific roles of each TCR hemichain in generating functional chain-centric TCR.

scientific article

TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses

scientific article published on 18 January 2019

Transient stimulation expands superior antitumor T cells for adoptive therapy.

scientific article published on 26 January 2017

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