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List of works by Mohammad T Mazhab-Jafari

A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues

scientific article published on 22 August 2013

An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis

scientific article

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

scientific article published on 24 October 2016

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

scientific article published on 18 May 2016

Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases

scientific article

Dynamically driven ligand selectivity in cyclic nucleotide binding domains

scientific article

Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP

scientific article published on 14 April 2008

Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening

scientific article published on 01 January 2009

Membrane-dependent modulation of the mTOR activator Rheb: NMR observations of a GTPase tethered to a lipid-bilayer nanodisc

scientific article

Molecular basis of human CD22 function and therapeutic targeting

scientific article published on 2 October 2017

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

scientific article published on 4 May 2015

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts

scientific article published on 28 June 2012

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

scientific article published on 14 December 2009

Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase

scientific article published on 29 May 2020

Structure-guided Mutation of the Conserved G3-box Glycine in Rheb Generates a Constitutively Activated Regulator of Mammalian Target of Rapamycin (mTOR)

scientific article

The auto-inhibitory role of the EPAC hinge helix as mapped by NMR

scientific article

The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.

scientific article published on 7 February 2012

Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states

scientific article published on 31 October 2007

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