List of works - Senena Corbalan

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

scientific article

A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.

scientific article published on May 2009

A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

scientific article published on 7 November 2002

Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols

scientific article published on 01 December 2001

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

scientific article

An infrared spectroscopic study of the secondary structure of protein kinase C alpha and its thermal denaturation

scientific article (publication date: 2 March 2004)

Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures

scientific article published on 05 July 2018

Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity

scientific article

Calorimetric Study of the Interaction of the C2 Domains of Classical Protein Kinase C Isoenzymes with Ca2+and Phospholipids†

scientific article published on 01 September 2004

Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.

scientific article

Characterization of the membrane binding mode of the C2 domain of PKC epsilon.

scientific article published in October 2003

Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate.

scientific article published on 27 November 2013

Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1.

scientific article published on 28 June 2018

Diacylglycerols as activators of protein kinase C.

scientific article

Diacylglycerols, multivalent membrane modulators.

scientific article published on 19 April 2007

Effect of calcium and phosphatidic acid binding on the C2 domain of PKC alpha as studied by Fourier transform infrared spectroscopy

scientific article published on 01 July 1999

Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.

scientific article published on 17 March 2006

Extensive proteolytic digestion of the (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum leads to a highly hydrophobic proteinaceous residue with a mainly alpha-helical structure

scientific article published on 01 July 1994

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

scientific article

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

scientific article

Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.

scientific article published on 24 August 2007

Intramolecular distances within the Ca(2+)-ATPase from sarcoplasmic reticulum as estimated through fluorescence energy transfer between probes

scientific article published on 01 October 1993

KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling

scientific article published on 15 October 2020

Location of N‐cyclohexyl‐N′‐(4‐dimethyl‐amino‐α‐naphthyl)carbodiimide‐binding site in sarcoplasmic reticulum Ca2+‐transporting ATPase ⬇️

scientific article published on 01 April 1998

Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.

scientific article

Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.

scientific article

Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities

scientific article published on September 2010

Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

scientific article published on 25 January 2006

Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.

scientific article

Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output

scientific article published on 16 December 2019

Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα

scientific article

Regulation of Sos Activity by Intramolecular Interactions ⬇️

scientific article published on February 1, 1998

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

scientific article published in July 2003

Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.

scientific article published on 13 January 2003

Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.

scientific article published on January 2004

Signaling through C2 domains: more than one lipid target

scientific article

Structural Study of the C2 Domains of the Classical PKC Isoenzymes Using Infrared Spectroscopy and Two-Dimensional Infrared Correlation Spectroscopy ⬇️

scientific article published on October 14, 2003

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

scientific article

Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains

scientific article

Study of the secondary structure of the C-terminal domain of the antiapoptotic protein bcl-2 and its interaction with model membranes

scientific article published on 01 July 2000

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

scientific article published on 13 April 2014

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

scientific article published on 9 August 2006

The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane

scientific article published on 01 September 2000

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding

scientific article published on 02 June 2007

The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.

scientific article

The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes

scientific article published on 13 July 2008

The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes

scientific article published on 15 February 2018

The role of the PH domain in the signal-dependent membrane targeting of Sos.

scientific article

The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

scientific article

The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains.

scientific article

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes.

scientific article

List of works by Senena Corbalan

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.

A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

An infrared spectroscopic study of the secondary structure of protein kinase C alpha and its thermal denaturation

Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures

Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity

Calorimetric Study of the Interaction of the C2 Domains of Classical Protein Kinase C Isoenzymes with Ca2+and Phospholipids†

Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.

Characterization of the membrane binding mode of the C2 domain of PKC epsilon.

Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate.

Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1.

Diacylglycerols as activators of protein kinase C.

Diacylglycerols, multivalent membrane modulators.

Effect of calcium and phosphatidic acid binding on the C2 domain of PKC alpha as studied by Fourier transform infrared spectroscopy

Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.

Extensive proteolytic digestion of the (Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum leads to a highly hydrophobic proteinaceous residue with a mainly alpha-helical structure

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.

Intramolecular distances within the Ca(2+)-ATPase from sarcoplasmic reticulum as estimated through fluorescence energy transfer between probes

KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling

Location of N‐cyclohexyl‐N′‐(4‐dimethyl‐amino‐α‐naphthyl)carbodiimide‐binding site in sarcoplasmic reticulum Ca2+‐transporting ATPase ⬇️

Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.

Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.

Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities

Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.

Phosphatidylinositol Monophosphates Regulate Optimal Vav1 Signaling Output

Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα

Regulation of Sos Activity by Intramolecular Interactions ⬇️

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.

Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.

Signaling through C2 domains: more than one lipid target

Structural Study of the C2 Domains of the Classical PKC Isoenzymes Using Infrared Spectroscopy and Two-Dimensional Infrared Correlation Spectroscopy ⬇️

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains

Study of the secondary structure of the C-terminal domain of the antiapoptotic protein bcl-2 and its interaction with model membranes

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding

The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.

The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes

The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes

The role of the PH domain in the signal-dependent membrane targeting of Sos.

The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains.

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes.