Search filters

List of works by Jean-Pierre Bourquin

A 14-month-old boy with cardiomegaly and heart failure

scientific article published on 01 January 1998

A mass spectrometric-derived cell surface protein atlas

scientific article

A precision medicine approach to haematological malignancies

scientific article

A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II

scientific article

AIEOP-BFM consensus guidelines 2016 for flow cytometric immunophenotyping of Pediatric acute lymphoblastic leukemia.

scientific article published on 10 February 2017

Accelerating drug development in pediatric cancer: a novel Phase I study design of venetoclax in relapsed/refractory malignancies.

scientific article published on 29 March 2018

Additional treatment with 2-Chloro-2-Deoxyadenosine during consolidation in children with high-risk acute myeloid leukemia does not improve survival.

scientific article published on 14 April 2015

Alternative technique for intrafemoral injection and bone marrow sampling in mouse transplant models

scientific article published on 12 June 2011

An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome

scientific article

CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage.

scientific article published on 25 November 2013

CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27-expressing B-cell malignancies.

scientific article published on 11 May 2017

CNS irradiation in pediatric acute myleoid leukemia: equal results by 12 or 18 Gy in studies AML-BFM98 and 2004

scientific article published on 07 April 2011

CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC.

scientific article published on 6 December 2017

Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts

scientific article

Characteristics and outcome in patients with central nervous system involvement treated in European pediatric acute myeloid leukemia study groups.

scientific article

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

scientific article

Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia.

scientific article published on 14 November 2016

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

scientific article

Durable remissions in TCF3-HLF positive acute lymphoblastic leukemia with blinatumomab and stem cell transplantation

scientific article published on 14 February 2019

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

scientific article published on 31 July 2019

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.

scientific article published on 25 January 2017

Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report

scientific article published on 04 October 2011

Favorable outcome of allogeneic hematopoietic stem cell transplantation for relapsed or refractory acute promyelocytic leukemia in childhood

scientific article published on 01 November 2004

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

scientific article published on 10 April 2015

Flow diagnostics essential code: a simple and brief format for the summary of leukemia phenotyping

scientific article published in July 2014

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia

scientific article published on 17 September 2013

From class waivers to precision medicine in paediatric oncology.

scientific article published in July 2017

Gemtuzumab ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group

scholarly article by Naghmeh Niktoreh et al published January 2019 in Haematologica

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.

scientific article published on 25 April 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Have chemosensitizing strategies for multidrug-resistant childhood acute lymphoblastic leukemia come of age?

scientific article published on August 2010

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

scientific article published on 12 September 2013

Humanised mouse models for haematopoiesis and infectious diseases

scientific article published on 9 November 2017

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 2 March 2018

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

scholarly article

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.

scientific article

Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics

scientific article published on 23 October 2019

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

scientific article

Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing

scientific article published on 2 February 2017

Inotuzumab ozogamicin in pediatric patients with relapsed/refractory acute lymphoblastic leukemia

scientific article published on 28 September 2018

Leukemia surfaceome analysis reveals new disease-associated features.

scientific article published on 6 May 2013

Long non-stop reading frames on the antisense strand of heat shock protein 70 genes and prion protein (PrP) genes are conserved between species.

scientific article published on December 1997

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

scientific article published on 30 May 2007

Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment

scientific article published on 9 March 2015

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

New Approaches to the Management of Adult Acute Lymphoblastic Leukemia

scientific article published on 21 September 2018

Opportunities and challenges in the immunological therapy of pediatric malignancy: a concise snapshot.

scientific article published on 12 August 2017

Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets

scientific article published on 01 October 2019

Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production

scientific article published in December 2009

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

scientific article published on 03 August 2018

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

scientific article published on 29 July 2019

Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

scientific article

RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo

scientific article published on 22 August 2017

Randomised Introduction of 2-CDA as Intensification during Consolidation for Children with High-risk AML--results from Study AML-BFM 2004.

scientific article published on 18 May 2015

Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004.

scientific article published on 23 May 2013

Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?

scientific article published on 11 June 2015

SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements ⬇️

scientific article published on August 1, 1998

Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16).

scientific article published on 26 September 2011

Single-cell analysis of structural variations and complex rearrangements with tri-channel processing

scientific article published on 23 December 2019

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012.

scientific article published on 22 February 2018

Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient.

scientific article published on 28 September 2013

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

scientific article published on 11 January 2017

Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia

scientific article

The CALM-AF10 fusion is a rare event in acute megakaryoblastic leukemia

scientific article published on 05 July 2007

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

scientific article published on 14 November 2019

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

scientific article

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

scientific article published on 27 June 2014

The clinical path to integrated genomics in ALL.

scientific article

Total body irradiation (TBI) in pediatric patients. A single-center experience after 30 years of low-dose rate irradiation.

scientific article

Treatment of an acute promyelocytic leukemia relapse using arsenic trioxide and all-trans-retinoic in a 6-year-old child.

scientific article published on 05 February 2014

Two versatile eukaryotic vectors permitting epitope tagging, radiolabelling and nuclear localisation of expressed proteins

scientific article published on 01 February 1996

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

scientific article published on 17 September 2018

Where can biology of childhood ALL be attacked by new compounds?

scientific article published on 12 March 2010

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

scientific article published on 01 April 2019

Paulina is supported by:

About Paulina

Help