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List of works by Paola Posocco

2-Difluoromethylene-4-methylenepentanoic Acid, A Paradoxical Probe Able To Mimic the Signaling Role of 2-Oxoglutaric Acid in Cyanobacteria

scientific article published on 05 May 2011

3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors

scientific article published on 8 July 2011

A 3D-pharmacophore model for sigma2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

scientific article published on 4 March 2010

A complete multiscale modelling approach for polymer-clay nanocomposites

scientific article published in August 2009

A simple new competition assay for heparin binding in serum applied to multivalent PAMAM dendrimers

scientific article published in May 2013

Adaptive Amphiphilic Dendrimer-Based Nanoassemblies as Robust and Versatile siRNA Delivery Systems

article

Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems

scientific article published on 12 September 2014

Anomerization of Acrylated Glucose During Traveling Wave Ion Mobility Spectrometry.

scientific article published on 4 June 2015

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance.

scientific article

Antimycobacterial activity of new 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-one derivatives. Molecular modeling investigations.

scientific article published on 3 May 2009

Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives.

scientific article published on 15 May 2009

Cationic carbosilane dendrimers and oligonucleotide binding: an energetic affair

scientific article published on March 2015

Chiral recognition at self-assembled multivalent (SAMul) nanoscale interfaces - enantioselectivity in polyanion binding

scientific article

Combination of dendrimer-nanovector-mediated small interfering RNA delivery to target Akt with the clinical anticancer drug paclitaxel for effective and potent anticancer activity in treating ovarian cancer

scientific article published on 18 March 2014

Conformational sensitivity of conjugated poly(ethylene oxide)-poly(amidoamine) molecules to cations adducted upon electrospray ionization - a mass spectrometry, ion mobility and molecular modeling study.

scientific article published on 29 August 2013

Copper(ii) binding to flexible triethanolamine-core PAMAM dendrimers: a combined experimental/in silico approach

scientific article published on 01 January 2014

Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake

scientific article

Double-degradable responsive self-assembled multivalent arrays--temporary nanoscale recognition between dendrons and DNA.

scientific article

Effects of primary amine-based coatings on microglia internalization of nanogels

scientific article published on 17 October 2019

Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer

scientific article

Electrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays - structure-activity effects on DNA/heparin binding

Exploring the Shape Influence on Melting Temperature, Enthalpy, and Solubility of Organic Drug Nanocrystals by a Thermodynamic Model

Gold nanoparticles with patterned surface monolayers for nanomedicine: current perspectives.

scientific article published in September 2017

Graphene oxide as a 2D platform for complexation and intracellular delivery of siRNA

scientific article published on 12 July 2019

Highly grafted polystyrene/polyvinylpyridine polymer gold nanoparticles in a good solvent: effects of chain length and composition

scientific article published on 16 March 2016

Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor.

scientific article published on 27 August 2011

Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

article

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study

scientific article published in February 2011

Impact of siRNA overhangs for dendrimer-mediated siRNA delivery and gene silencing.

scientific article published on 25 July 2013

In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.

scientific article published on 9 September 2013

Iron-mediated interaction of alpha synuclein with lipid raft model membranes

scientific article published on 27 February 2020

Mallard blue: a high-affinity selective heparin sensor that operates in highly competitive media

scientific article published on 13 February 2013

Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing

scientific article

Mimicking the 2-oxoglutaric acid signalling function using molecular probes: insights from structural and functional investigations

scientific article published on 01 July 2014

Mix and Match: Coassembly of Amphiphilic Dendrimers and Phospholipids Creates Robust, Modular, and Controllable Interfaces

scientific article

Mixed Fluorinated/Hydrogenated Self-Assembled Monolayer-Protected Gold Nanoparticles: In Silico and In Vitro Behavior

scientific article published on 03 April 2019

Molecular dynamics reveal BCR-ABL1 polymutants as a unique mechanism of resistance to PAN-BCR-ABL1 kinase inhibitor therapy.

scientific article published on 18 February 2014

Morphological control of self-assembled multivalent (SAMul) heparin binding in highly competitive media

scientific article published on 30 May 2017

Nano tools for macro problems: multiscale molecular modeling of nanostructured polymer systems

PAMAM dendrimers for siRNA delivery: computational and experimental insights

scientific article published in July 2010

Patchy and Janus Nanoparticles by Self-Organization of Mixtures of Fluorinated and Hydrogenated Alkanethiolates on the Surface of a Gold Core

scientific article published on 23 September 2016

Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV).

scientific article published on 29 January 2010

Phase Behavior of Gradient Copolymer Melts with Different Gradient Strengths Revealed by Mesoscale Simulations

scientific article published on 23 October 2020

Polymer-clay nanocomposites: a multiscale molecular modeling approach

scientific article published on 10 February 2007

Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering.

scientific article published on 9 April 2018

Rationalizing the F⋯S interaction discovered within a tetrafluorophenylazido-containing bola-phospholipid

scientific article published on 08 February 2012

Scripting approach in hybrid organic–inorganic condensation simulation: the GPTMS proof-of-concept

Self-Assembled Multivalent (SAMul) Polyanion Binding-Impact of Hydrophobic Modifications in the Micellar Core on DNA and Heparin Binding at the Peripheral Cationic Ligands

scientific article

Self-Organization of Mixtures of Fluorocarbon and Hydrocarbon Amphiphilic Thiolates on the Surface of Gold Nanoparticles

scientific article published on 27 July 2012

Self-assembled multivalent RGD-peptide arrays--morphological control and integrin binding

scientific article published on 5 April 2013

Shape-Persistent and Adaptive Multivalency: Rigid Transgeden (TGD) and Flexible PAMAM Dendrimers for Heparin Binding

scientific article published on 26 June 2014

Simple, Fast, and Accurate In silico Estimations of Contact Angle, Surface Tension, and Work of Adhesion of Water and Oil Nanodroplets on Amorphous Polypropylene Surfaces

scientific article published on 16 May 2012

Sodium montmorillonite silylation: unexpected effect of the aminosilane chain length.

scientific article published on August 2010

Structural Requirements of 2-Oxoglutaric Acid Analogues To Mimic Its Signaling Function

scientific article published on 29 August 2013

Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus.

scientific article published on 22 November 2011

Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil

scientific article published on 26 January 2019

Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.

scientific article published on 25 June 2010

Synthesis and characterization of UV photocrosslinkable hydrogels with poly(N-vinyl-2-pyrrolidone): Determination of the network mesh size distribution

Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

scientific article published in September 2009

Tell me something I do not know. Multiscale molecular modeling of dendrimer/ dendron organization and self-assembly in gene therapy.

scientific article published on January 2012

The interaction of β2-microglobulin with gold nanoparticles: impact of coating, charge and size

scientific article published on 06 September 2018

Theoretical Importance of PVP-Alginate Hydrogels Structure on Drug Release Kinetics

scientific article published on 18 April 2019

Through the open door: Preferential binding of dasatinib to the active form of BCR-ABL unveiled by in silico experiments

scientific article published on 15 June 2013

Tuning the Properties of Nanogel Surfaces by Grafting Charged Alkylamine Brushes

scientific article published on 24 October 2019

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