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List of works by Tracy M Bryan

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

scientific article published on 8 June 2015

A mechanism for the extension and unfolding of parallel G-quadruplexes by human telomerase at single-molecule resolution

scientific article published on 29 July 2020

APC mutations occur early during colorectal tumorigenesis

scientific article published on September 17, 1992

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

scientific journal article

Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

scientific article published on September 1995

Alternative lengthening of telomeres: dangerous road less travelled

scientific article

Amplification of telomerase reverse transcriptase gene in human mammary epithelial cells with limiting telomerase RNA expression levels

scientific article

Association of extended in vitro proliferative potential with loss of p16INK4 expression.

scientific article

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

scientific article

Clinical and functional characterization of telomerase variants in patients with pediatric acute myeloid leukemia/myelodysplastic syndrome

scientific article published on 21 April 2020

Direct involvement of the TEN domain at the active site of human telomerase

scientific article

ESI-MS Investigation of an Equilibrium between a Bimolecular Quadruplex DNA and a Duplex DNA/RNA Hybrid.

scientific article

End Products of Telomere Research

scientific article published on 01 June 2020

Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells

scientific article published on 22 July 2019

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

scientific article published on 01 November 1997

Extension of G-quadruplex DNA by ciliate telomerase

scientific article

G-Quadruplexes at Telomeres: Friend or Foe?

scientific article published on 13 August 2020

G-Quadruplexes: From Guanine Gels to Chemotherapeutics ⬇️

scientific article published on October 1, 2011

G-quadruplexes: from guanine gels to chemotherapeutics

scientific article published on 01 January 2010

G-ruption: the third international meeting on G-quadruplex and G-assembly

scientific article published on 10 September 2012

Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension

scientific article published on 7 March 2018

I-motif DNA structures are formed in the nuclei of human cells.

scientific article published on 23 April 2018

Identification of FAP locus genes from chromosome 5q21

scientific article

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers ⬇️

scientific article published on March 15, 1991

Immortalized cells with no detectable telomerase activity. A review

scientific article published on November 1, 1997

Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

scientific article published on June 2008

Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.

scientific article

Interrogation of G-quadruplex-protein interactions

scientific article published on December 2007

Involvement of RB-1, p53, p16INK4 and telomerase in immortalisation of human cells.

scientific article

Mechanisms of DNA Replication and Repair: Insights from the Study of G-Quadruplexes

scientific article published on 22 September 2019

Multiple DNA-binding sites in Tetrahymena telomerase

scientific article published on 03 January 2008

Normal telomere maintenance in immortal ataxia telangiectasia cell lines ⬇️

scientific article published on October 6, 1997

Physiological relevance of telomeric G-quadruplex formation: a potential drug target

scientific article published on February 2007

Quantitative assays for measuring human telomerase activity and DNA binding properties.

scientific article

Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids

scientific article published on June 1999

Structure of stem-loop IV of Tetrahymena telomerase RNA.

scientific article published on 15 June 2006

Targeted therapy of <i>TERT</i>-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy

scientific article published on 11 December 2020

Telomerase Recognizes G-Quadruplex and Linear DNA as Distinct Substrates†

scientific article published on 18 September 2007

Telomerase promotes formation of a telomere protective complex in cancer cells

scientific article published on 02 October 2019

Telomerase recruitment requires both TCAB1 and Cajal bodies independently

scientific article

Telomerase recruitment to telomeres

scientific article published on January 2008

Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax

scientific article

Telomere dynamics and telomerase activity in in vitro immortalised human cells ⬇️

scientific article published on April 1, 1997

Telomere elongation in immortal human cells without detectable telomerase activity

scientific article

Telomere length dynamics in telomerase-positive immortal human cell populations.

scientific article published in March 1998

Telomeres in the Haemopoietic System ⬇️

scientific article published on January 1, 1997

Telomeric G-quadruplexes are a substrate and site of localization for human telomerase

scientific article published on 9 July 2015

Tetrahymena telomerase is active as a monomer

scientific article

The APC gene product in normal and tumor cells

scientific article

The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA.

scientific article

The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

scientific article published on June 1997

Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.

scientific article

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.

scientific article

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