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List of works by Michael Theisen

A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

scientific article published on 26 February 2015

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

scientific article published on 6 November 2012

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

research work

A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

scientific article (publication date: 16 February 2017)

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

scientific article published on 28 July 2016

A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children

scientific article

A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2--a GLURP-MSP3 fusion protein malaria vaccine candidate

scientific article published on 22 February 2011

A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria

scientific article published on 22 June 2013

Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors

scientific article published on 27 September 2016

Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice

scientific article

Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth ⬇️

scientific article published on August 1, 2011

Antibodies to malaria vaccine candidates are associated with chloroquine or sulphadoxine/pyrimethamine treatment efficacy in children in an endemic area of Burkina Faso

scientific article published on 22 March 2012

Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

scientific article published on 27 February 2016

Antibody responses to a panel of Plasmodium falciparum malaria blood-stage antigens in relation to clinical disease outcome in Sudan.

scientific article published on 31 October 2008

Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana

scientific article

Antigenicity and immunogenicity of recombinant glutamate-rich protein of Plasmodium falciparum expressed in Escherichia coli

scientific article

Assessing malaria transmission in a low endemicity area of north-western Peru.

scientific article published on 22 September 2013

Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII–V in Ghanaian children living in two communities with varying malaria transmission patterns

scientific article published on 8 January 2018

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies.

scientific article published on 14 January 2013

Breadth of Functional Antibodies Is Associated With Plasmodium falciparum Merozoite Phagocytosis and Protection Against Febrile Malaria

scientific article published on 01 June 2019

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

scientific article published on 12 January 2021

Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam.

scientific article

Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

scientific article

Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2

scientific article published on 01 September 2019

Cytophilic Antibodies Against Key Plasmodium falciparum Blood Stage Antigens Contribute to Protection Against Clinical Malaria in a High Transmission Region of Eastern India.

scientific article published on 4 May 2018

Determination of beta-defensin genomic copy number in different populations: A comparison of three methods

scientific article

Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure

scientific article published on 23 July 2012

Distinct patterns of blood-stage parasite antigens detected by plasma IgG subclasses from individuals with different level of exposure to Plasmodium falciparum infections

scientific article published on 26 October 2010

Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana

scientific article published on 5 January 2018

Efficacy of the GMZ2 malaria vaccine in African children

scientific article published in January 2017

Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

scientific article published on 23 June 2017

Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children

scientific article

FcγRIIa polymorphism and anti-malaria-specific IgG and IgG subclass responses in populations differing in susceptibility to malaria in Burkina Faso.

scientific article published in June 2012

Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibition

scientific article published on 20 July 2012

Genetic polymorphisms in the glutamate-rich protein of Plasmodium falciparum field isolates from a malaria-endemic area of Brazil

scientific article published on June 2013

High-Throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

scientific article

Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia

scientific article published on 5 February 2013

IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children.

scientific article published on October 1999

Immunogenicity of a recombinant fusion construct composed of intrinsically unstructured, low polymorphic segments derived from merozoite surface protein 2 and trophozoite exported protein 1

scientific article published on 26 July 2019

Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations

scientific article published on 13 December 2011

Immunogenicity of the Plasmodium falciparum glutamate-rich protein expressed by vaccinia virus

scientific article

Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display

scientific article published on 31 May 2017

Inflammatory reactions in placental blood of Plasmodium falciparum‐infected women and high concentrations of soluble E‐selectin and a circulating P. falciparum protein in the cord sera ⬇️

scientific article published on February 1, 1998

Is Fc gamma receptor IIA (FcγRIIA) polymorphism associated with clinical malaria and Plasmodium falciparum specific antibody levels in children from Burkina Faso?

scientific article published on 31 October 2014

Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

scientific article published on 5 April 2018

Malaria epidemiology in an area of stable transmission in tribal population of Jharkhand, India

scholarly article

Microscopic and sub-microscopic asymptomatic Plasmodium falciparum infections in Ghanaian children and protection against febrile malaria

scientific article published on 27 July 2020

Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria

scholarly article published by Ikhlaq H Kana in 2018

Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

scientific article published on 23 August 2017

Naturally Acquired Antibodies Target the Glutamate-Rich Protein on Intact Merozoites and Predict Protection Against Febrile Malaria.

scientific article published on 21 February 2017

Naturally acquired antibody responses to recombinant Pfs230 and Pfs48/45 transmission blocking vaccine candidates

scientific article published on 11 April 2015

Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon

scientific article published on 15 February 2012

Novel overlapping coding sequences in Chlamydia trachomatis

scientific article published on 13 October 2006

Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and Ghana

scientific article published on 23 March 2020

Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum.

scientific article

Plasmodium falciparum Clag9-Associated PfRhopH Complex Is Involved in Merozoite Binding to Human Erythrocytes

scientific article published on 22 January 2020

Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infection.

scientific article

Plasmodium falciparum merozoite surface antigen-specific cytophilic IgG and control of malaria infection in a Beninese birth cohort

scientific article published on 11 June 2019

Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children

scientific article

Potential Impact of Seasonal Malaria Chemoprevention on the Acquisition of Antibodies Against Glutamate-Rich Protein and Apical Membrane Antigen 1 in Children Living in Southern Senegal

scientific article published on 17 August 2015

Protein-protein interaction studies reveal the Plasmodium falciparum merozoite surface protein-1 region involved in a complex formation that binds to human erythrocytes

scientific article published on 6 March 2018

Recent advances in recombinant protein-based malaria vaccines

scientific article

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

scientific article published on 26 April 2017

Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura

scientific article published on 18 October 2012

SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion ⬇️

scientific article published in PLoS ONE

Sero-epidemiological evaluation of changes in Plasmodium falciparum and Plasmodium vivax transmission patterns over the rainy season in Cambodia

scientific article

Stage‑specific Plasmodium falciparum immune responses in afebrile adults and children living in the Greater Accra Region of Ghana

scientific article published on 10 February 2020

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

scientific article published on 16 March 2016

The GMZ2 malaria vaccine: from concept to efficacy in humans.

scientific article

The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is a pure and stable

scientific article published on 02 December 2019

Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine

scientific article published on 03 January 2017

Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants

scientific article

Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity

scientific article published on 8 February 2018

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