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List of works by John Frater

A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

scientific article

A cure for HIV: is it in sight?

scientific article published on 19 April 2014

A pilot evaluation of whole blood finger-prick sampling for point-of-care HIV viral load measurement: the UNICORN study.

scientific article

Adaptation of HIV-1 to human leukocyte antigen class I

scientific article published on 25 February 2009

Advancing the HIV cure agenda: the next 5 years.

scientific article published on February 2015

Beating atomic swords into immunological ploughshares

scientific article published on 01 July 2011

Booster Vaccination Against SARS-CoV-2 Induces Potent Immune Responses in People With Human Immunodeficiency Virus

scientific article published on 13 January 2023

Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients

scientific article published on 08 June 2020

Broadly neutralizing antibody responses in the longitudinal primary HIV-1 infection Short Pulse Anti-Retroviral Therapy at Seroconversion cohort

scientific article published on 14 June 2021

CD32 expressing doublets in HIV-infected gut-associated lymphoid tissue are associated with a T follicular helper cell phenotype

scientific article published on 25 June 2019

CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA.

scientific article

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

scientific article published on 17 December 2006

Co-operative additive effects between HLA alleles in control of HIV-1

scientific article published on 19 October 2012

Current understanding in HIV immunopathology and treatment

scientific article published on 31 January 2012

Cytotoxic T-Lymphocyte Escape Mutations Identified by HLA Association Favor Those Which Escape and Revert Rapidly ⬇️

scientific article published on June 6, 2012

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

scientific article published on 22 November 2017

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints

scientific article published on 05 February 2014

Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection

scientific article published on 15 June 2015

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

scientific article published on 10 March 2022

Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy

scientific article published on 25 October 2013

Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection

scientific article published on 18 December 2012

Early antiretroviral therapy reduces HIV DNA following perinatal HIV infection

scientific article

Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

scientific article published on 04 June 2021

Epigenetic scars of CD8<sup>+</sup> T cell exhaustion persist after cure of chronic infection in humans

scientific article published on 26 July 2021

European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease

scientific article published on 26 April 2009

Evaluation of Viremia Frequencies of a Novel Human Pegivirus by Using Bioinformatic Screening and PCR

scientific article

Evaluation of a novel automated volumetric flow cytometer for absolute CD4+ T lymphocyte quantitation.

scientific article

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection

scientific article

Failure to detect xenotropic murine leukemia virus-related virus in blood of individuals at high risk of blood-borne viral infections

scientific article

HIV control through a single nucleotide on the HLA-B locus

scientific article published on 15 August 2012

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

scientific article

HIV-1 DNA predicts disease progression and post-treatment virological control

scientific article

HIV-1 resistance genotyping by sequencing produces inconsistent results for mixed viral populations

article

HIV-1-specific CD4(+) responses in primary HIV-1 infection predict disease progression

scientific article published on March 2014

HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703

scientific article published on 15 April 2011

High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.

scientific article

Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function

scientific article

Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis-Specific T-Cell Responses

scientific article published on 13 March 2018

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

scientific article published on 6 February 2016

Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

scientific article published in 2021

Immunological biomarkers predict HIV-1 viral rebound after treatment interruption

scientific article

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

scientific article published in December 2014

Impact of pre-adapted HIV transmission.

scientific article published on 16 May 2016

Increased levels of CD4 T-cell activation in individuals with CXCR4 using viruses in primary HIV-1 infection

scientific article published on April 2012

Inhibitory killer cell immunoglobulin-like receptors strengthen CD8 T cell-mediated control of HIV-1, HCV, and HTLV-1

article

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes

scientific article published on 15 May 2013

Longitudinal analysis of an HLA-B*51-restricted epitope in integrase reveals immune escape in early HIV-1 infection

scientific article

Low copy target detection by Droplet Digital PCR through application of a novel open access bioinformatic pipeline, 'definetherain'

scientific article

Mapping the drivers of within-host pathogen evolution using massive data sets

scientific article published on 09 July 2019

Mapping the drivers of within-host pathogen evolution using massive data sets

Modelling the evolution and spread of HIV immune escape mutants

scientific article

Mutagenically separated PCR assay for rapid detection of M41L and K70R zidovudine resistance mutations in CRF01_AE (subtype E) human immunodeficiency virus type 1.

scientific article

New approaches in HIV eradication research.

scientific article published on December 2011

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

scientific article published in September 2016

P02-10. Plant expression of chimeric Gag/gp41 virus-like particles as a mucosally-targeted subunit vaccine against HIV-1.

scientific article

P07-09. Contemporaneous transmission of genetically distinct HIV variants from a single donor to two recipients.

scientific article published on 22 October 2009

P12-16. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR.

scientific article published on 22 October 2009

P16-56 LB. Novel tetramer technology for the detection of high affinity CD8 T cells

Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants

scientific article

Post-treatment control or treated controllers? Viral remission in treated and untreated primary HIV infection

scientific article published on 04 January 2017

Precise identification of a human immunodeficiency virus type 1 antigen processing mutant

scientific article published on 15 November 2006

Prevalence of HIV type-1 drug-associated mutations in pre-therapy patients in the Free State, South Africa

scientific article published in January 2009

Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations

scientific article

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS

scholarly article

Short Communication: Lack of Effect of Maraviroc Intensification on Blood and Gut Reservoir.

scientific article published on 4 December 2016

Short-course antiretroviral therapy in primary HIV infection

scientific article

Simple detection of point mutations associated with HIV-1 drug resistance.

scientific article published in April 2001

Structured observations reveal slow HIV-1 CTL escape

scientific article

Tenofovir Disoproxil Fumarate Fails to Prevent HIV Acquisition or the Establishment of a Viral Reservoir: Two Case Reports

scientific article published on 9 January 2016

The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recen

scientific article published on 5 April 2022

The Role of CD4+ T Follicular Helper Cells in HIV Infection: From the Germinal Center to the Periphery

scientific article published on 30 January 2017

The impact of HIV-1 subtype on the clinical response on HAART

scientific article published on November 1, 2002

The impact of immunoglobulin in acute HIV infection on the HIV reservoir: a randomized controlled trial.

scientific article

Thirty years of treating HIV-1 infection: where next?

scientific article published in April 2015

Towards an HIV cure: science and debate from the International AIDS Society 2013 symposium.

scientific article

Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment.

scientific article published on 12 April 2018

Virological Blips and Predictors of Post Treatment Viral Control After Stopping ART Started in Primary HIV Infection.

scientific article

Virus immune evasion: new mechanism and implications in disease outcome.

scientific article published on 24 September 2012

Widespread impact of HLA restriction on immune control and escape pathways of HIV-1

scientific article published on 29 February 2012

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