List of works - Jagannadha Sastry

2257: Vaccine efficacy and immunogenicity of recombinant WAP and CAP-1 proteins in AKR mice

scientific article published in September 2017

A Replicating Single-cycle Adenovirus Vaccine against Ebola Virus

scientific article published in 2018

A comparison of cell-mediated immune responses in rhesus macaques housed singly, in pairs, or in groups

scientific article published in May 2000

A novel HIV vaccine strategy

scientific article published on 01 January 1990

A post-CD4-binding step involving interaction of the V3 region of viral gp120 with host cell surface glycosphingolipids is common to entry and infection by diverse HIV-1 strains

scientific article published on December 2002

A synthetic peptide from the first conserved region in the envelope protein gp160 is a strong T-cell epitope in HIV-infected chimpanzees and humans

scientific article published in January 1998

A two-codon mutant of cholera toxin lacking ADP-ribosylating activity functions as an effective adjuvant for eliciting mucosal and systemic cellular immune responses to peptide antigens

scientific article

Adenosine kinase deficiency in tritiated deoxyadenosine-resistant mouse S49 lymphoma cell lines.

scientific article

Adipocytes impair efficacy of antiretroviral therapy

scientific article published on 6 April 2018

Age- and Sex-associated Differences in Phenotypic and Functional Characteristics of Peripheral Blood Lymphocytes in Chimpanzees (Pan troglodytes).

scientific article published on September 2017

Alpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens.

scientific article

Amplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines

scientific article

Cervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers

scientific article published on November 2003

Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccines

scientific article

Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.

scientific article published on 03 July 2013

Correction: Minimally invasive monitoring of CD4 T cells at multiple mucosal tissues after intranasal vaccination in rhesus macaques

scientific article

Corrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques"

scientific article published on 29 October 2020

Critical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection

scientific article published on 23 February 2007

Cross-reactive T-cell proliferative responses to V3 peptides corresponding to different geographical HIV-1 isolates in HIV-seropositive individuals

article

Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.

scientific article

Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region

scientific article published on 01 October 1996

Dendritic cells enhance detection of antigen-specific cellular immune responses by lymphocytes from rhesus macaques immunized with an HIV envelope peptide cocktail vaccine

scientific article published in April 2003

Differences in functional immune responses of high vs. low hardy healthy individuals.

scientific article

Divergent HIV-1-Directed Immune Responses Generated by Systemic and Mucosal Immunization with Replicating Single-Cycle Adenoviruses in Rhesus Macaques

article

Dynein light chain 1 peptide inhibits human immunodeficiency virus infection in eukaryotic cells.

scientific article

Effect of antibiotics on gut and vaginal microbiomes associated with cervical cancer development in mice

scientific article published on 11 September 2020

Effects of dominance status and environmental enrichment on cell-mediated immunity in rhesus macaques

Effects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus.

scientific article published on November 1994

Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study

scientific article published on 18 June 2018

Enhancement of Mucosal Immunogenicity of Viral Vectored Vaccines by the NKT Cell Agonist Alpha-Galactosylceramide as Adjuvant

scientific article

Evaluation of cellular immune responses in rhesus monkeys subjected to adenovirus-mediated gene transfer into the cervix

scientific article published in May 1999

Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon

article

Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.

scientific article published in August 1996

Extramedullary hematopoiesis in the mandibular lymph node of simian-human immunodeficiency virus-infected rhesus monkeys (Macaca mulatta): a report of three cases.

scientific article published in March 2004

Flow cytometric analysis of macaque whole blood for antigen-specific intracellular cytokine production by T lymphocytes

scientific article published on 01 February 2003

Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques

scientific article

Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

scientific article published on 22 February 2021

HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex

scientific article published on 23 April 2013

Human Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma

scientific article published on 01 January 2020

Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients.

scientific article

Identification of T-cell epitopes without B-cell activity in the first and second conserved regions of the HIV Env protein ⬇️

scientific article published on 01 June 1991

Impairment of antigen-specific cellular immune responses under simulated microgravity conditions

scientific article published in April 2001

Improving the sensitivity of the ELISPOT analyses of antigen-specific cellular immune responses in rhesus macaques

scientific article published in January 2005

Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates.

scientific article

Induction of human immunodeficiency virus-specific T cell responses in rhesus monkeys by synthetic peptides from gp160.

scientific article published in March 1993

Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques

scientific article published on 27 April 2016

Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120 ⬇️

scientific article published on November 1, 1993

Intranasal Therapeutic Peptide Vaccine Promotes Efficient Induction and Trafficking of Cytotoxic T Cell Response for the Clearance of HPV Vaginal Tumors

scientific article published on 29 May 2020

Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8⁺ T Lymphocytes in the Female Reproductive Tract.

scientific article published on 17 March 2016

Intranasal but not intravenous delivery of the adjuvant α-galactosylceramide permits repeated stimulation of natural killer T cells in the lung.

scientific article published on 19 September 2011

Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection

scientific article

Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study

scientific article published on 26 September 2005

Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer

scientific article published on 12 July 2018

Lymphocytes upregulate CD36 in adipose tissue and liver

scientific article published on 01 December 2019

Mapping of the CXCR4 binding site within variable region 3 of the feline immunodeficiency virus surface glycoprotein.

scientific article published on 2 July 2008

Membrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection ⬇️

scientific article (publication date: March 1992)

Minimally invasive monitoring of CD4 T cells at multiple mucosal tissues after intranasal vaccination in rhesus macaques.

scientific article published on 8 December 2017

Mucoadhesive wafers composed of binary polymer blends for sublingual delivery and preservation of protein vaccines

scientific article published on 20 December 2020

Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV Oral Cancers

scientific article published on 27 July 2018

Multicolor flow cytometry analyses of cellular immune response in rhesus macaques.

scientific article published on 22 April 2010

Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy

scientific article

Natural killer T cell and TLR9 agonists as mucosal adjuvants for sublingual vaccination with clade C HIV-1 envelope protein

scientific article

Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.

scientific article

Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans

scientific article

Oral immunization of rhesus macaques with adenoviral HIV vaccines using enteric-coated capsules.

scientific article

Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis).

scientific article

Presence of HLA-C-restricted cytotoxic T-lymphocyte responses in long-term nonprogressors infected with human immunodeficiency virus

scientific article published on January 1998

Prime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques

scientific article

Procedures for mucosal immunization and analyses of cellular immune response to candidate HIV vaccines in murine and nonhuman primate models.

scientific article published on January 2014

Prophylactic Sublingual Immunization with Mycobacterium tuberculosis Subunit Vaccine Incorporating the Natural Killer T Cell Agonist Alpha-Galactosylceramide Enhances Protective Immunity to Limit Pulmonary and Extra-Pulmonary Bacterial Burden in Mic

scientific article published on 6 December 2017

Protection against Mucosal SHIV Challenge by Peptide and Helper-Dependent Adenovirus Vaccines

scientific article published on December 2009

Protection against chronic infection and AIDS by an HIV envelope peptide-cocktail vaccine in a pathogenic SHIV-rhesus model

scientific article published in December 2001

Protection by dendritic cells-based HIV synthetic peptide cocktail vaccine: preclinical studies in the SHIV-rhesus model

scientific article published on 01 March 2005

Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120.

scientific article

Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells

article

SHIV transmission and susceptibility to re-exposure through social contact following vaccination with an HIV synthetic peptide-cocktail: a case study.

scientific article

Selective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail

scientific article published on 24 October 2007

Selective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid.

scientific article published in October 1985

Sequential CD134-CXCR4 interactions in feline immunodeficiency virus (FIV): soluble CD134 activates FIV Env for CXCR4-dependent entry and reveals a cryptic neutralization epitope.

scientific article

Studies on V3-specific cross-reactive T-cell responses in chimpanzees chronically infected with HIV-1IIIB.

scientific article published in June 1995

Studies on in vivo induction of HIV-1 envelope-specific cytotoxic T lymphocytes by synthetic peptides from the V3 loop region of HIV-1 IIIB gp 120.

scientific article published in February 1995

Studies on in vivo induction of cytotoxic T lymphocyte responses by synthetic peptides from E6 and E7 oncoproteins of human papillomavirus type 16

scientific article published on 01 January 1995

Sublingual injection of microparticles containing glycolipid ligands for NKT cells and subunit vaccines induces antibody responses in oral cavity

scientific article published on 03 December 2014

Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.

scientific article

Synthesis of exocellular proteins during the exponential and stationary phase of growth of Bacillus megaterium

scientific article published on 01 January 1981

TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells.

scientific article published on 21 September 2009

Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer

scientific article published on 18 September 2019

The Botanical Glycoside Oleandrin Inhibits Human T-cell Leukemia Virus Type-1 Infectivity and Env-Dependent Virological Synapse Formation

scientific article published on 21 August 2019

The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections

scientific article

Trans-urocanic acid enhances tenofovir alafenamide stability for long-acting HIV applications

scientific article published on 11 July 2020

Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis

article

Transgene expression in the rhesus cervix mediated by an adenovirus expressing beta-galactosidase.

scientific article published in April 1996

Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm

scientific article published on 28 August 2018

Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine.

scientific article

Use of helper T cell-inducing peptides from conserved regions in HIV-1 env in a noncovalent mixture with a CTL-inducing V3-loop peptide for in vivo induction of long-lasting systemic CTL response

scientific article published in January 1994

Viral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant

scientific article published on 17 October 2020

List of works by Jagannadha Sastry

2257: Vaccine efficacy and immunogenicity of recombinant WAP and CAP-1 proteins in AKR mice

A Replicating Single-cycle Adenovirus Vaccine against Ebola Virus

A comparison of cell-mediated immune responses in rhesus macaques housed singly, in pairs, or in groups

A novel HIV vaccine strategy

A post-CD4-binding step involving interaction of the V3 region of viral gp120 with host cell surface glycosphingolipids is common to entry and infection by diverse HIV-1 strains

A synthetic peptide from the first conserved region in the envelope protein gp160 is a strong T-cell epitope in HIV-infected chimpanzees and humans

A two-codon mutant of cholera toxin lacking ADP-ribosylating activity functions as an effective adjuvant for eliciting mucosal and systemic cellular immune responses to peptide antigens

Adenosine kinase deficiency in tritiated deoxyadenosine-resistant mouse S49 lymphoma cell lines.

Adipocytes impair efficacy of antiretroviral therapy

Age- and Sex-associated Differences in Phenotypic and Functional Characteristics of Peripheral Blood Lymphocytes in Chimpanzees (Pan troglodytes).

Alpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens.

Amplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines

Cervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers

Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccines

Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.

Correction: Minimally invasive monitoring of CD4 T cells at multiple mucosal tissues after intranasal vaccination in rhesus macaques

Corrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques"

Critical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection

Cross-reactive T-cell proliferative responses to V3 peptides corresponding to different geographical HIV-1 isolates in HIV-seropositive individuals

Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.

Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region

Dendritic cells enhance detection of antigen-specific cellular immune responses by lymphocytes from rhesus macaques immunized with an HIV envelope peptide cocktail vaccine

Differences in functional immune responses of high vs. low hardy healthy individuals.

Divergent HIV-1-Directed Immune Responses Generated by Systemic and Mucosal Immunization with Replicating Single-Cycle Adenoviruses in Rhesus Macaques

Dynein light chain 1 peptide inhibits human immunodeficiency virus infection in eukaryotic cells.

Effect of antibiotics on gut and vaginal microbiomes associated with cervical cancer development in mice

Effects of dominance status and environmental enrichment on cell-mediated immunity in rhesus macaques

Effects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus.

Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study

Enhancement of Mucosal Immunogenicity of Viral Vectored Vaccines by the NKT Cell Agonist Alpha-Galactosylceramide as Adjuvant

Evaluation of cellular immune responses in rhesus monkeys subjected to adenovirus-mediated gene transfer into the cervix

Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon

Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.

Extramedullary hematopoiesis in the mandibular lymph node of simian-human immunodeficiency virus-infected rhesus monkeys (Macaca mulatta): a report of three cases.

Flow cytometric analysis of macaque whole blood for antigen-specific intracellular cytokine production by T lymphocytes

Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques

Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex

Human Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma

Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients.

Identification of T-cell epitopes without B-cell activity in the first and second conserved regions of the HIV Env protein ⬇️

Impairment of antigen-specific cellular immune responses under simulated microgravity conditions

Improving the sensitivity of the ELISPOT analyses of antigen-specific cellular immune responses in rhesus macaques

Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates.

Induction of human immunodeficiency virus-specific T cell responses in rhesus monkeys by synthetic peptides from gp160.

Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques

Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120 ⬇️

Intranasal Therapeutic Peptide Vaccine Promotes Efficient Induction and Trafficking of Cytotoxic T Cell Response for the Clearance of HPV Vaginal Tumors

Intranasal Vaccination Affords Localization and Persistence of Antigen-Specific CD8⁺ T Lymphocytes in the Female Reproductive Tract.

Intranasal but not intravenous delivery of the adjuvant α-galactosylceramide permits repeated stimulation of natural killer T cells in the lung.

Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection

Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study

Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer

Lymphocytes upregulate CD36 in adipose tissue and liver

Mapping of the CXCR4 binding site within variable region 3 of the feline immunodeficiency virus surface glycoprotein.

Membrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection ⬇️

Minimally invasive monitoring of CD4 T cells at multiple mucosal tissues after intranasal vaccination in rhesus macaques.

Mucoadhesive wafers composed of binary polymer blends for sublingual delivery and preservation of protein vaccines

Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV Oral Cancers

Multicolor flow cytometry analyses of cellular immune response in rhesus macaques.

Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy

Natural killer T cell and TLR9 agonists as mucosal adjuvants for sublingual vaccination with clade C HIV-1 envelope protein

Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.

Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans

Oral immunization of rhesus macaques with adenoviral HIV vaccines using enteric-coated capsules.

Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis).

Presence of HLA-C-restricted cytotoxic T-lymphocyte responses in long-term nonprogressors infected with human immunodeficiency virus

Prime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques

Procedures for mucosal immunization and analyses of cellular immune response to candidate HIV vaccines in murine and nonhuman primate models.

Prophylactic Sublingual Immunization with Mycobacterium tuberculosis Subunit Vaccine Incorporating the Natural Killer T Cell Agonist Alpha-Galactosylceramide Enhances Protective Immunity to Limit Pulmonary and Extra-Pulmonary Bacterial Burden in Mic

Protection against Mucosal SHIV Challenge by Peptide and Helper-Dependent Adenovirus Vaccines

Protection against chronic infection and AIDS by an HIV envelope peptide-cocktail vaccine in a pathogenic SHIV-rhesus model

Protection by dendritic cells-based HIV synthetic peptide cocktail vaccine: preclinical studies in the SHIV-rhesus model

Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120.

Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells

SHIV transmission and susceptibility to re-exposure through social contact following vaccination with an HIV synthetic peptide-cocktail: a case study.

Selective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail

Selective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid.

Sequential CD134-CXCR4 interactions in feline immunodeficiency virus (FIV): soluble CD134 activates FIV Env for CXCR4-dependent entry and reveals a cryptic neutralization epitope.