List of works by William James

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

scientific article

A novel real time imaging platform to quantify macrophage phagocytosis

scientific article published on 27 July 2016

A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection

scientific article

A rodent cell line permissive for entry and reverse transcription of human immunodeficiency virus type 1 has a pre-integration block to productive infection.

scientific article published on October 1994

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

scientific article published on 20 January 2022

Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells.

scientific article published in February 1997

An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction

scientific article

An immunodominant NP<sub>105-113</sub>-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

scientific article published on 01 December 2021

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 15 October 2020

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells.

scientific article

Cell-surface heparan sulfate facilitates human immunodeficiency virus Type 1 entry into some cell lines but not primary lymphocytes.

scientific article published on April 1999

Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.

scientific article

Climate Change. A multidisciplinary Approach

A textbook on Climate Change

Comparison of p24 measurement by ELISA versus indicator cells for detecting residual HIV infectivity in vitro

scientific article published on 01 April 1996

Competing intrachain interactions regulate the formation of beta-sheet fibrils in bovine PrP peptides.

scientific article published on March 2003

Conformational pH dependence of intermediate states during oligomerization of the human prion protein.

scientific article published on 24 January 2008

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

scientific article published on April 2012

Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

scientific article published on 15 October 2012

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

scientific article published on 10 March 2022

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

scientific article published on 17 February 2016

Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation.

scientific article

Episomal transgene expression in pluripotent stem cells.

scientific article

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages

scientific article published on 21 August 2017

First workshop of the MRC AIDS-directed programme, 9-10 November 1987, Central Public Health Laboratory, Colindale, London, UK

scientific article published on 01 June 1988

Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells

scientific article published on 18 May 2011

Gene inhibition of HIV-1 replication. A comparative and mechanistic study

scientific article published on October 28, 1992

Generation of neutralizing aptamers against herpes simplex virus type 2: potential components of multivalent microbicides.

scientific article

HIV-1 infects macrophages by exploiting an endocytic route dependent on dynamin, Rac1 and Pak1.

scientific article

HIV-1 pseudotype virus containing a Cocal virus genome and an HIV envelope: construction, assay and use.

scientific article published on October 1993

Heterokaryons formed between a rat myeloma and a mouse fibroblast are permissive for entry of HIV type 1.

scientific article published on December 1994

Host-adaptive antigenic variation in Bunyaviruses.

scientific article published on December 1986

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.

scientific article published on 18 January 2017

Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro.

scientific article published on November 1993

Inhibition of human immunodeficiency virus replication in cell culture by endogenously synthesized antisense RNA.

scientific article published on September 1990

Inter-oligomer interactions of the human prion protein are modulated by the polymorphism at codon 129.

scientific article published on 29 May 2008

Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.

scientific article published on August 1993

LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease.

scientific article published on February 2017

Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: implications for disease susceptibility to Creutzfeldt-Jakob disease.

scientific article

Molecular epidemiology of dengue virus type 3 in Venezuela.

scientific article published on June 2003

Molecular heterosis of prion protein beta-oligomers. A potential mechanism of human resistance to disease

scientific article published on 15 September 2006

Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers ⬇️

scientific article published on December 1, 2003

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 13 July 2020

Nucleic acid and polypeptide aptamers: a powerful approach to ligand discovery.

scientific article

Oligomerization of the human prion protein proceeds via a molten globule intermediate

scientific article published on 08 January 2007

PCR and the cloning of receptor subtype genes.

scientific article published on September 1989

Physiological characterisation of human iPS-derived dopaminergic neurons

scientific article

Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site

scientific article published on 01 December 1995

Protection of HIV neutralizing aptamers against rectal and vaginal nucleases: implications for RNA-based therapeutics

scientific article

Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection

scientific article published on 10 June 2011

Proteomic-based identification of CD4-interacting proteins in human primary macrophages

scientific article

RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

scientific article published on 24 September 2018

SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus

scientific article published in 2020

Several commercially available anti-CCR5 monoclonal antibodies lack specificity and should be used with caution.

scientific article

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

scientific article published on 31 July 2020

Structural characterization of a 2'F-RNA aptamer that binds a HIV-1 SU glycoprotein, gp120.

scientific article

Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1.

scientific article

Structural determinants of conformationally selective, prion-binding aptamers.

scientific article

Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2

scientific article published on 01 January 2022

The 5' leader of the mRNA encoding the marek's disease virus serotype 1 pp14 protein contains an intronic internal ribosome entry site with allosteric properties.

scientific article published on 30 September 2009

The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

scientific article

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

scientific article published on 8 April 2005

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.

scientific article published on 22 January 2014

Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.

scientific article

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.

scientific article published on 17 August 2016

Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

scientific article published in 2023

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