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List of works by Ian J Tickle

A new generation of crystallographic validation tools for the protein data bank

scientific article

Adaptation of plasminogen activator sequences to known protease structures

scientific article published on 01 July 1983

Anisotropic thermal motion and polypeptide secondary structure studied by X-ray analysis at 0.98A resolution

scientific article published on 01 January 1985

Calculated tyrosyl circular dichroism of proteins: absence of tryptophan and cystine interferences in avian pancreatic polypeptide

scientific article published on 01 March 1982

Crystal Structure of the Marburg Virus VP35 Oligomerization Domain

scientific article

Crystallization of 5-aminolaevulinic acid dehydratase from Escherichia coli and Saccharomyces cerevisiae and preliminary X-ray characterization of the crystals.

scientific article published on August 1997

Detection of secondary binding sites in proteins using fragment screening

scientific article

Engineering a change in metal-ion specificity of the iron-dependent superoxide dismutase from Mycobacterium tuberculosis-- X-ray structure analysis of site-directed mutants

scientific article

Engineering of an intersubunit disulfide bridge in the iron-superoxide dismutase of Mycobacterium tuberculosis

scientific article

Error estimates of protein structure coordinates and deviations from standard geometry by full-matrix refinement of gammaB- and betaB2-crystallin.

scientific article

Estimation of weights and validation: a marginal likelihood approach

scientific article

Experimental determination of optimal root-mean-square deviations of macromolecular bond lengths and angles from their restrained ideal values

scientific article published on 16 November 2007

Fragment screening using X-ray crystallography.

scientific article

Fragment-based lead discovery using X-ray crystallography.

scientific article published in January 2005

Homology among acid proteases: comparison of crystal structures at 3A resolution of acid proteases from Rhizopus chinensis and Endothia parasitica ⬇️

scientific article published on February 1, 1977

Insulin polymorphism: some physical and biological properties of rat insulins

scientific article published on 01 February 1978

MOLPACK: molecular graphics for studying the packing of protein molecules in the crystallographic unit cell.

scientific article published in March 1991

PDB_REDO: automated re-refinement of X-ray structure models in the PDB.

scientific article

Polypeptide hormone-receptor interactions: the structure and receptor binding of insulin and glucagon ⬇️

scientific article published on January 1, 1977

Receptor-binding region of insulin ⬇️

scientific article published on February 5, 1976

Rfree and the rfree ratio. I. Derivation of expected values of cross-validation residuals used in macromolecular least-squares refinement.

scientific article published in July 1998

Rfreeand theRfreeratio. II. Calculation of the expected values and variances of cross-validation statistics in macromolecular least-squares refinement

article

Statistical quality indicators for electron-density maps

scientific article published on 16 March 2012

Structural studies on avian pancreatic polypeptide [proceedings]

scientific article published on January 1, 1977

Structure of oligomeric beta B2-crystallin: an application of the T2 translation function to an asymmetric unit containing two dimers

scientific article published on 01 December 1991

Structure of pentameric human serum amyloid P component

scientific article

Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO

scientific article

The conformation and receptor binding of pancreatic hormones

scientific article published on 01 February 1981

The conformation of deamino-oxytocin: X-ray analysis of the 'dry' and 'wet' forms

scientific article published on 01 April 1990

The crystal structures of three non-pancreatic human insulins

scientific article published on 01 December 1983

The low resolution structure analysis of an acid proteinase from Endothia parasitica

scientific article published on December 25, 1975

The molecular structure and stability of the eye lens: X-ray analysis of γ-crystallin II

scientific article published in Nature

The relation of polypeptide hormone structure and flexibility to receptor binding: The relevance of X-ray studies on insulins, glucagon and human placental lactogen ⬇️

scientific article published on July 31, 1975

The relation of structure to storage and receptor binding of glucagon ⬇️

scientific article published on November 1, 1976

The structure at 0.3nm (3A) resolution of the acid proteinase from Endothia parasitica [proceedings]

scientific article published on 01 January 1977

The structures of crystalline complexes of human serum amyloid P component with its carbohydrate ligand, the cyclic pyruvate acetal of galactose

scientific article

The use of protein homologues in the rotation function

scientific article published on 01 March 1993

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae.

scientific article published on May 1999

X-Ray Analysis and Circular Dichroism of the Acid Protease from Endothia Parasitica and Chymosin

scientific article published on January 1, 1977

X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution

scientific article

X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus

scientific article

X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen

scientific article

X-ray analysis of glucagon and its relationship to receptor binding ⬇️

scientific article published on October 30, 1975

X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase

scientific article published in December 1997

XModeScore: a novel method for accurate protonation/tautomer-state determination using quantum-mechanically driven macromolecular X-ray crystallographic refinement

scientific article

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