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List of works by Kian Leong Lee

A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles.

scientific article published on 23 May 2016

Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer.

scientific article

Author Correction: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

scientific article published on 20 July 2018

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

scientific article

Graded Nodal/Activin Signaling Titrates Conversion of Quantitative Phospho-Smad2 Levels into Qualitative Embryonic Stem Cell Fate Decisions ⬇️

scientific article published on June 23, 2011

Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells

scientific article

Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state

scientific article

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.

scientific article

Hypoxia regulates microRNA expression in the human carotid body

scientific article published on 23 February 2017

Hypoxia-induced arterial differentiation requires adrenomedullin and notch signaling

scientific article published on 12 February 2013

Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway

scientific article published on 16 November 2017

Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression.

scientific article

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells

article published in 2010

PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells.

scientific article published on 03 September 2013

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition.

scientific article published on 4 April 2014

S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.

scientific article published on 26 October 2016

Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.

scientific article

The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer.

scientific article published on 11 August 2015

The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms.

scientific article published on November 2013

The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth.

scientific article

Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling.

scientific article published on 30 August 2012

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