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List of works by David Haselbach

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation

scientific article published on 25 July 2017

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation

scientific article

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.

scientific article

HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain

scientific article published on 22 July 2021

Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.

scientific article

Mechanism of APC/CCDC20 activation by mitotic phosphorylation

scientific article published on 25 April 2016

Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism

scientific article published on 23 June 2020

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space

scientific article (publication date: September 2015)

Quantifying the heterogeneity of macromolecular machines by mass photometry

scientific article published on 14 April 2020

Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters

scientific article published on 23 May 2019

Structural basis for cooperativity of CRM1 export complex formation

scientific article

Structural determinants and mechanism of mammalian CRM1 allostery

scientific article published on 11 July 2013

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