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Authors whose works are in public domain in at least one jurisdiction

List of works by Timothy Vyse

1-50 of 145 results

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

scientific article

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

scientific article

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

scientific journal article

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus

scientific article published on 29 July 2007

Defining the role of the MHC in autoimmunity: a review and pooled analysis

scientific article

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

scholarly article

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

scientific article published on 6 October 2013

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

article

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

scientific article

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

scientific article published on 21 October 2009

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

scientific article

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

scientific article published on October 27, 2011

Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus

scientific article

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

scientific article published on 02 December 2007

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

scholarly article

HLA has strongest association with IgA nephropathy in genome-wide analysis

scientific article

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap

scientific article

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

scientific article

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility

scientific article

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

scientific article published on 29 March 2012

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus

scientific article

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

scientific article published on 11 July 2016

Identification of two independent risk factors for lupus within the MHC in United Kingdom families

scientific article

Common variants within MECP2 confer risk of systemic lupus erythematosus

scientific article

Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus

scientific article published on 30 June 2011

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans

scientific article published on April 2009

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

scientific article published on 27 December 2011

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

scientific article

Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

scientific article

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

scientific article

The genetics of SLE: an update in the light of genome-wide association studies

scientific article

A polymorphism within IL21R confers risk for systemic lupus erythematosus

scientific article published on August 2009

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation

scientific article published on 7 October 2012

Transancestral mapping and genetic load in systemic lupus erythematosus

scientific article published on 17 July 2017

Selective IgA deficiency in autoimmune diseases

scientific article published on 4 August 2011

The genetics of lupus: a functional perspective

scientific article published on May 29, 2012

C-reactive protein in rheumatology: biology and genetics

scientific article published on 05 April 2011

Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study

scientific article

MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus

scientific article

Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans

scientific article

Genetic associations of LYN with systemic lupus erythematosus

scientific article published on 16 April 2009

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production

scientific article

Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus

scientific article published on April 2009

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci

scientific article published on 04 June 2013

Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

scientific article published on 17 August 2012

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups

scientific article published on April 2009

The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus

scientific article

Association of LY9 in UK and Canadian SLE families

scientific article published on 24 January 2008

Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations

scientific article

Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G

scientific article published on 10 January 2012