List of works by Piotr Lewczuk

A Practical Guide to Immunoassay Method Validation

scientific article

A Specific Reduction in Aβ1-42 vs. a Universal Loss of Aβ Peptides in CSF Differentiates Alzheimer's Disease From Meningitis and Multiple Sclerosis.

scientific article published on 24 May 2018

A comment on the paper 'Biomarkers in Multiple Sclerosis' by Sapko et al

scientific article published on 07 October 2020

Adherence-dependent shifts in the patterns of beta-amyloid peptides secreted by human mononuclear phagocytes.

scientific article published on 3 June 2008

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease

scientific article published on 22 April 2019

Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load.

scientific article published on 24 January 2007

Amyloid beta peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease

scientific article

Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing.

scientific article published on 5 August 2009

Amyloid β oligomers (AβOs) in Alzheimer's disease

scientific article published in December 2017

Amyloid-β 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays.

scientific article published in January 2015

Analysis of Surface Levels of IL-1 Receptors and Macrophage Scavenger Receptor I in Peripheral Immune Cells of Patients With Alzheimer Disease

scientific article published on 24 April 2019

Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map.

scientific article published in February 2004

Application of multiplexing technology to the analysis of the intrathecally released immunoglobulins against B. burgdorferi antigens in neuroborreliosis

scientific article published on 22 July 2015

Assessing the commutability of reference material formats for the harmonization of amyloid-β measurements

article

Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia.

scientific article published in January 2011

Association of SORL1 gene variants with Alzheimer's disease

scientific article published on 3 February 2009

Association of systemic inflammation markers with the presence and extent of coronary artery calcification

scientific article

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

scientific article published on 7 September 2014

Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease

scientific article published on 11 January 2012

Biomarkers for the Diagnosis of Alzheimer's Disease in Clinical Practice: The Role of CSF Biomarkers during the Evolution of Diagnostic Criteria

scientific article published on 2 August 2022

Biomarkers of Alzheimer's disease and mild cognitive impairment: a current perspective

scientific article published on 09 December 2014

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

scientific article published on 18 November 2016

Blood-based neurochemical diagnosis of vascular dementia: a pilot study.

scientific article published on 27 July 2007

CSF Aβ1-42 - an excellent but complicated Alzheimer's biomarker - a route to standardisation

scientific article

CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia

scientific article

CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction

CSF biomarker variability in the Alzheimer's Association quality control program

scientific article published on May 2013

CSF diagnosis of Alzheimer's disease and dementia with Lewy bodies.

scientific article

CSF markers in amyotrophic lateral sclerosis

scientific article published on 04 May 2012

CSF nonphosphorylated Tau as a biomarker for the discrimination of AD from CJD

scientific article published on 26 May 2018

Cardiac Surgery is Associated with Biomarker Evidence of Neuronal Damage

scientific article published on 11 March 2020

Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer's Disease

scholarly article by Barbara Mroczko published in June 2018

Cerebral and extracerebral cholesterol metabolism and CSF markers of Alzheimer's disease

scientific article published on 3 January 2013

Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer's Disease

scientific article published on 14 October 2016

Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

scientific article published on 13 May 2017

Cerebrospinal fluid amyloidβ peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloidβ peptides

scholarly article by Mirko Bibl et al published September 2004 in Electrophoresis

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

scientific article published on 27 October 2017

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

scientific article published on April 2009

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

scientific article

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type

scientific article published on 31 October 2014

Cerebrospinal fluid leakage--reliable diagnostic methods

scientific article published on 17 February 2011

Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype

scientific article published on January 2010

Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review

scientific article

Cerebrospinal fluid soluble amyloid-β protein precursor as a potential novel biomarkers of Alzheimer's disease.

scientific article published in January 2012

Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias.

scientific article published on 7 December 2010

Cerebrospinal fluid under non-steady state condition caused by plasmapheresis

Characterization of acid sphingomyelinase activity in human cerebrospinal fluid

scientific article

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls

scientific article published on July 2015

Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease.

scientific article published on 23 August 2012

Cholesterol metabolites and plant sterols in cerebrospinal fluid are associated with Alzheimer´s cerebral pathology and clinical disease progression

scientific article published on 07 November 2020

Clinical significance of fluid biomarkers in Alzheimer's Disease

scientific article published on 08 May 2020

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease

scientific article

Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia

scientific article

Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease.

scientific article published on 14 January 2009

Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics

scientific article published in March 2016

Concentrations of matrix metalloproteinases and their tissue inhibitors in the cerebrospinal fluid of patients with Alzheimer's disease.

scientific article

Confirmation rate of blinded (99m)Tc-SPECT compared to neurochemical dementia biomarkers in CSF in patients with Alzheimer disease.

scientific article published on 7 August 2010

Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia.

scientific article

Decreased circulating CD34+ stem cells in early Alzheimer's disease: Evidence for a deficient hematopoietic brain support?

scientific article published on 10 October 2006

Differential processing and secretion of Abeta peptides and sAPPalpha in human platelets is regulated by thrombin and prostaglandine 2.

scientific article published on 5 February 2008

Digit ratio (2D:4D) and academic success as measured by achievement in the academic degree "Habilitation"

Distinct fractional Abeta release patterns in human mononuclear phagocytes.

scientific article published on 27 September 2008

Do we still need positron emission tomography for early Alzheimer's disease diagnosis?

scientific article published on 6 July 2016

Effect of Sample Collection Tubes on Cerebrospinal Fluid Concentrations of Tau Proteins and Amyloid Peptides

scientific article published on 01 February 2006

Electrophoretic separation of amyloid beta peptides in plasma.

scientific article

Elevated soluble intercellular adhesion molecule-1 levels in obesity: relationship to insulin resistance and tumor necrosis factor-alpha system activity

scientific article published in January 2002

Endothelin B receptor deficiency augments neuronal damage upon exposure to hypoxia-ischemia in vivo

scientific article published in July 2002

Erlangen Score Predicts Cognitive and Neuroimaging Progression in Mild Cognitive Impairment Stage of Alzheimer's Disease

scientific article published on 01 January 2019

Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer's disease

scientific article published on 05 January 2019

Erratum: aCaMKII Autophosphorylation Controls the Establishment of Alcohol Drinking Behavior

scholarly article published in Neuropsychopharmacology

Erythropoietin therapy for acute stroke is both safe and beneficial

scientific article

Evaluation of Visinin-Like Protein 1 Concentrations in the Cerebrospinal Fluid of Patients with Mild Cognitive Impairment as a Dynamic Biomarker of Alzheimer's Disease

scholarly article by Barbara Mroczko et al published 2 December 2014 in Journal of Alzheimer's Disease

Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment

scientific article

Excessive daytime sleepiness in a patient with coexisting myotonic dystrophy type 1, myasthenia gravis and Graves' disease

scientific article published on 3 February 2017

First amyloid β1-42 certified reference material for re-calibrating commercial immunoassays

scientific article published on 04 August 2020

Glial Fibrillary Acidic Protein in Serum is Increased in Alzheimer's Disease and Correlates with Cognitive Impairment

scientific article published on 01 January 2019

Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium

scientific article published on 28 December 2012

Guidelines for the standardized collection of blood-based biomarkers in psychiatry: Steps for laboratory validity - a consensus of the Biomarkers Task Force from the WFSBP

scientific article published on 25 March 2019

HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy

scientific article

Heart fatty acid binding protein as a potential diagnostic marker for neurodegenerative diseases.

scientific article

High Performance Proteomics: 7th HUPO Brain Proteome Project Workshop March 7-9, 2007 Wellcome Trust Conference Centre, Hinxton, UK.

scientific article published in August 2007

Hippocampal volume differences between healthy young apolipoprotein E ε2 and ε4 carriers

scientific article published in January 2011

Histologically confirmed amyloid deposition and low CSF Abeta42 in a cognitively normal subject

scientific article published on 14 March 2007

Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease

scientific article published in January 2009

Homocysteine metabolism is associated with cerebrospinal fluid levels of soluble amyloid precursor protein and amyloid beta

scientific article

Immune complexes of auto-antibodies against A beta 1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients.

scientific article published on 6 February 2007

Impact of telmisartan on the inflammatory state in patients with coronary atherosclerosis--influence on IP-10, TNF-α and MCP-1

scientific article published on 28 March 2013

Increased concentration of the CSF Tau protein and its phosphorylated form in the late juvenile metachromatic leukodystrophy form: a case report

scientific article published on 24 May 2012

Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia

scientific article published on 10 October 2017

Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease.

scientific article

Influence of brain-derived neurotrophic factor and apolipoprotein E genetic variants on hemispheric and lateral ventricular volume of young healthy adults

scientific article

Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults

scientific article published on 29 December 2010

Interlaboratory proficiency processing scheme in CSF aliquoting: implementation and assessment based on biomarkers of Alzheimer's disease

International quality control survey of neurochemical dementia diagnostics.

scientific article published on 11 October 2006

Intrathecal IgG synthesis in patients with alterations in the neurochemical dementia diagnostics

scientific article published in January 2010

Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38.

scientific article published in January 2004

Lyme borreliosis: from pathogenesis to diagnosis and treatment

scientific article published on 13 September 2012

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in the tumors of central nervous system (CNS).

scientific article published on 24 December 2013

Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form

scientific article

Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons

scientific article published in August 2005

Microvesicles from cerebrospinal fluid of patients with Alzheimer's disease display reduced concentrations of tau and APP protein

scientific article published on 08 May 2019

Multidimensional plasma protein separation technique for identification of potential Alzheimer's disease plasma biomarkers: a pilot study

scientific article published on 14 March 2012

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.

scientific article published on 19 January 2007

Multiplexing analysis of the polyspecific intrathecal immune response in multiple sclerosis

article

Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases.

scientific article published on April 2008

Neurochemical dementia diagnostics for Alzheimer's disease and other dementias: an ISO 15189 perspective

scientific article published on October 2012

Neurochemical dementia diagnostics in Alzheimer's disease: where are we now and where are we going?

scientific article published on August 2011

Neurochemical dementia diagnostics: State of the art and research perspectives

scientific article published on March 2008

Neurochemical dementia diagnostics: a simple algorithm for interpretation of the CSF biomarkers.

scientific article published on 4 August 2009

Neurochemical dementia diagnostics: assays in CSF and blood

scientific article

Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau.

scientific article

Neurofilament ELISA validation.

scientific article published on 24 October 2009

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease

scientific article

Neuroprotein dynamics in the cerebrospinal fluid: intraindividual concomitant ventricular and lumbar measurements

scientific article

Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer's Disease: Analytical and Diagnostic Characterization

scientific article published on 20 September 2016

Nuclear medicine diagnostic techniques in the era of pathophysiology-based CSF biomarkers for Alzheimer's disease

scientific article

PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment

scientific article published on 12 March 2020

Perfusion Imaging with SPECT in the Era of Pathophysiology-Based Biomarkers for Alzheimer's Disease

scientific article published on 15 December 2010

Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes

scientific article

Plasma amyloid-beta peptides in acute cerebral ischemia: a pilot study.

scientific article published in July 2012

Plasma concentrations of the amyloid-β peptides in young volunteers: the influence of the APOE genotype

scientific article published in January 2014

Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.

scientific article published in April 2009

Plasma homocysteine levels in patients with normal tension glaucoma

scientific article published in December 2010

Plasma levels of sRANKL and OPG are associated with atherogenic cytokines in patients with intermediate cardiovascular risk

scientific article

Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer's disease

scientific article published on 28 July 2018

Preanalytical Sample Handling and Sample Stability Testing for the Neurochemical Dementia Diagnostics

scholarly article by Rüdiger Zimmermann et al published 5 August 2011 in Journal of Alzheimer's Disease

Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides

scientific article

Proinflammatory cytokines are involved in the initiation of the abnormal matrix process in pseudoexfoliation syndrome/glaucoma

scientific article

Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI.

scientific article

Reduced CSF carboxyterminally truncated Aβ peptides in frontotemporal lobe degenerations

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease

scientific article

Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest

scientific article published on 13 April 2019

Serum levels of the Th1 chemoattractant interferon-gamma-inducible protein (IP) 10 are elevated in patients with essential hypertension.

scientific article

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study.

scientific article published on 29 July 2008

Spontaneous magnetoencephalographic activity in patients with obsessive-compulsive disorder

scientific article published on 6 December 2006

Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative

scientific article

Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease

scientific article published on 4 June 2005

Surface Trafficking of APP and BACE in Live Cells.

scientific article published on 14 April 2015

Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature

scientific article

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

scientific article

The German Competence Net Dementias: standard operating procedures for the neurochemical dementia diagnostics

scientific article

The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide

scientific article published in January 2003

The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative

scientific article published on 20 August 2014

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review

scientific article published on 23 June 2018

The influence of insulin infusion on the metabolism of amyloid β peptides in plasma

scientific article

The sortilin-related receptor SORL1 and the amyloid cascade: a possible explanation for the concurrent elevation of CSF soluble APPalpha and APPbeta in Alzheimer's disease

scientific article published in May 2010

Trabalho de consenso de força-tarefa da WFSBP sobre marcadores biológicos das demências: contribuição da análise do LCR e do sangue para o diagnóstico precoce e diferencial das demências

Transient increase of plasma concentrations of amyloid β peptides after electroconvulsive therapy

scientific article published on 12 March 2011

Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects

scientific article

Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: evidence for novel Abeta species

scientific article published in October 2007

Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias.

scientific article

Validation of the Erlangen Score Algorithm for Differential Dementia Diagnosis in Autopsy-Confirmed Subjects

Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects

scientific article published on September 2015

Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects

scientific article published in December 2015

Ventricular and lumbar cerebrospinal fluid concentrations of Alzheimer's disease biomarkers in patients with normal pressure hydrocephalus and posttraumatic hydrocephalus.

scientific article

Vergleichende Sensitivität der neurochemischen Demenzdiagnostik im Liquor und rCBF im99mTc-SPECT bei Patienten mit Alzheimerdemenz

article published in 2009

White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation.

scientific article published on 15 March 2018

[Physical activity and prevention of Alzheimer's dementia: current evidence and feasibility of an interventional trial].

scientific article published on 12 March 2009

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases

scientific article

αCaMKII autophosphorylation controls the establishment of alcohol drinking behavior

scientific article published on 04 March 2013

Paulina is supported by:

About Paulina

Help