List of works - Fleur M Ferguson

Binding hotspots of BAZ2B bromodomain: Histone interaction revealed by solution NMR driven docking.

scientific article

Characterization of a highly selective inhibitor of the Aurora kinases.

scientific article published on 10 August 2017

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

scientific article published on 04 August 2020

Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

scientific article

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

scientific article published on 13 August 2020

Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

scientific article published on 16 April 2020

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

scientific article published on 28 March 2019

Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors

scientific article published on 2 August 2016

Discovery of a selective inhibitor of doublecortin like kinase 1

scientific article published on 06 April 2020

Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold

scientific article published on 13 September 2019

Kinase inhibitors: the road ahead.

scientific article published on 16 March 2018

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

scientific article published on 01 December 2020

Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.

scientific article published on 18 December 2014

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

scientific article published on 18 September 2020

Selective Mediator dependence of cell-type-specifying transcription

scientific article published on 01 June 2020

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

scientific article published on 31 August 2018

Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

scientific article published on 03 November 2019

Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold

scientific article published on 12 June 2020

Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14

scientific article published on 23 May 2019

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

scientific article published on 25 March 2019

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

scientific article

Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors

scientific article published on 03 March 2020

List of works by Fleur M Ferguson

Binding hotspots of BAZ2B bromodomain: Histone interaction revealed by solution NMR driven docking.

Characterization of a highly selective inhibitor of the Aurora kinases.

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Scaffold"

Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors

Discovery of a selective inhibitor of doublecortin like kinase 1

Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold

Kinase inhibitors: the road ahead.

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

Selective Mediator dependence of cell-type-specifying transcription

Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains

Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold

Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors