List of works - Jörg Schaarschmidt

A Newly Discovered TSHR Variant (L665F) Associated With Nonautoimmune Hyperthyroidism in an Austrian Family Induces Constitutive TSHR Activation by Steric Repulsion Between TM1 and TM7

scientific article published on 20 June 2014

Assessment of contact predictions in CASP12: co-evolution and deep learning coming of age.

scientific article published on 26 October 2017

Controversial constitutive TSHR activity: patients, physiology, and in vitro characterization

scientific article published on 20 May 2014

Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis

scientific article published on 06 April 2011

Identification of novel TSH interaction sites by systematic binding analysis of the TSHR hinge region.

scientific article published on 31 May 2011

Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor.

scientific article

Large-scale prediction of binding affinity in protein–small ligand complexes: the PRODIGY-LIG web server

scientific article published on 01 May 2019

Late manifestation of subclinical hyperthyroidism after goitrogenesis in an index patient with a N670S TSH receptor germline mutation masquerading as TSH receptor antibody negative Graves' disease.

scientific article published on 4 July 2012

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity

scientific article published on 16 December 2018

Performance of HADDOCK and a simple contact-based protein-ligand binding affinity predictor in the D3R Grand Challenge 2.

scientific article

Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation

scientific article published on 26 April 2016

Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents.

scientific article published on 8 June 2014

SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots.

scientific article published on 14 August 2017

The DisVis and PowerFit Web Servers: Explorative and Integrative Modeling of Biomolecular Complexes.

scientific article published on 6 December 2016

The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH.

scientific article published on 16 August 2011

The leipzig thyrotropin receptor mutation database: update 2012.

scientific article published on 22 September 2012

List of works by Jörg Schaarschmidt