List of works - Stacie K Loftus

A Sox10 expression screen identifies an amino acid essential for Erbb3 function

scientific article

A combined genetic and radiation hybrid map surrounding the Treacher Collins syndrome locus on chromosome 5q.

scientific article published on November 1993

A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation

scientific article published in October 2003

A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway

scientific article

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

scientific journal article

Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1

scientific journal article

Comparison of melanoblast expression patterns identifies distinct classes of genes

scientific article

Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer.

scientific article published in January 2004

Decreased melanoma proliferation and cell survival: turn down your SOX10 ⬇️

scientific article published on January 1, 2013

Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A.

scientific article

Frequent mutations in the MITF pathway in melanoma

scientific article published on 29 April 2009

Generation of RCAS vectors useful for functional genomic analyses.

scientific article published in October 2001

Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage

scientific article

Genomic Organization of the Human Heparan Sulfate-N-Deacetylase/N-Sulfotransferase Gene: Exclusion from a Causative Role in the Pathogenesis of Treacher Collins Syndrome

article

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

scientific article

Gpnmb is a melanoblast-expressed, MITF-dependent gene

scientific article

Hypoxia-induced HIF1α targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis

scientific article published on 6 February 2017

Identification and functional analysis of SOX10 phosphorylation sites in melanoma

scientific article published on 9 January 2018

Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish

scientific article

Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes

scientific article

Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene

scientific article

Loci associated with skin pigmentation identified in African populations.

scientific article published on 12 October 2017

Meeting report: 16th International Mouse Genome Conference.

scientific article published in September 2003

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene ⬇️

scientific article published on July 11, 1997

Mutation of melanosome protein RAB38 in chocolate mice

scientific article

Networks and pathways in pigmentation, health, and disease

scientific article

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

scientific article

Oligodendroglial and pan-neural crest expression of Cre recombinase directed by Sox10 enhancer

scientific article

SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis

scientific article published on August 2013

SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer

scientific article

Sox proteins in melanocyte development and melanoma

scientific article

Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders

scientific article published on June 2004

Substantial narrowing of the Niemann-Pick C candidate interval by yeast artificial chromosome complementation.

scientific article published on July 1997

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.

scientific article

The next generation of melanocyte data: Genetic, epigenetic, and transcriptional resource datasets and analysis tools.

scientific article published on 16 January 2018

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling

scientific article

List of works by Stacie K Loftus

A Sox10 expression screen identifies an amino acid essential for Erbb3 function

A combined genetic and radiation hybrid map surrounding the Treacher Collins syndrome locus on chromosome 5q.

A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation

A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1

Comparison of melanoblast expression patterns identifies distinct classes of genes

Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer.

Decreased melanoma proliferation and cell survival: turn down your SOX10 ⬇️

Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A.

Frequent mutations in the MITF pathway in melanoma

Generation of RCAS vectors useful for functional genomic analyses.

Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage

Genomic Organization of the Human Heparan Sulfate-N-Deacetylase/N-Sulfotransferase Gene: Exclusion from a Causative Role in the Pathogenesis of Treacher Collins Syndrome

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

Gpnmb is a melanoblast-expressed, MITF-dependent gene

Hypoxia-induced HIF1α targets in melanocytes reveal a molecular profile associated with poor melanoma prognosis

Identification and functional analysis of SOX10 phosphorylation sites in melanoma

Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish

Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes

Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene

Loci associated with skin pigmentation identified in African populations.

Meeting report: 16th International Mouse Genome Conference.

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene ⬇️

Mutation of melanosome protein RAB38 in chocolate mice

Networks and pathways in pigmentation, health, and disease

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

Oligodendroglial and pan-neural crest expression of Cre recombinase directed by Sox10 enhancer

SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis

SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer

Sox proteins in melanocyte development and melanoma

Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders

Substantial narrowing of the Niemann-Pick C candidate interval by yeast artificial chromosome complementation.

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.

The next generation of melanocyte data: Genetic, epigenetic, and transcriptional resource datasets and analysis tools.

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling