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List of works by Xudong Qu

A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids

scientific article published on 29 July 2019

Activation of Natural Products Biosynthetic Pathways via a Protein Modification Level Regulation.

scientific article published on 31 May 2017

Biosynthesis of optically pure chiral alcohols by a substrate coupled and biphasic system with a short-chain dehydrogenase from Streptomyces griseus.

scientific article

Biosynthesis of plant tetrahydroisoquinoline alkaloids through an imine reductase route

scientific article published on 18 November 2019

Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production

scientific article published on 03 August 2012

Caerulomycins and collismycins share a common paradigm for 2,2'-bipyridine biosynthesis via an unusual hybrid polyketide-peptide assembly Logic.

scientific article published on 23 May 2012

Characterization of a SAM-dependent fluorinase from a latent biosynthetic pathway for fluoroacetate and 4-fluorothreonine formation in Nocardia brasiliensis

scientific article

Characterization of the Biosynthetic Gene Cluster for the Antibiotic Armeniaspirols in Streptomyces armeniacus

scientific article published on 12 February 2019

Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase.

scientific article

Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.

scientific article published in March 2011

Deciphering Carbamoylpolyoxamic Acid Biosynthesis Reveals Unusual Acetylation Cycle Associated with Tandem Reduction and Sequential Hydroxylation.

scientific article published on August 2016

Deciphering Piperidine Formation in Polyketide-Derived Indolizidines Reveals a Thioester Reduction, Transamination, and Unusual Imine Reduction Process.

scientific article published on 28 October 2016

Draft Genome Sequence of Marine Bacterium Streptomyces sp. Strain CNQ431, a Producer of the Cytokine Inhibitor Splenocin

scientific article

Efficient biosynthesis of heterodimeric C-aryl pyrroloindoline alkaloids

scientific article published in Nature Communications

Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system

scientific article published on 02 March 2019

Enzymatic O-Glycosylation of Etoposide Aglycone by Exploration of the Substrate Promiscuity for Glycosyltransferases

scientific article published on 10 December 2019

Expanding the Bioactive Chemical Space of Anthrabenzoxocinones through Engineering the Highly Promiscuous Biosynthetic Modification Steps.

scientific article published on 11 December 2017

Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.

scientific article published on June 2006

Identifying the Minimal Enzymes for Unusual Carbon-Sulfur Bond Formation in Thienodolin Biosynthesis

scientific article published on 21 March 2016

Insights into pyrroindomycin biosynthesis reveal a uniform paradigm for tetramate/tetronate formation

scientific article published on 15 October 2012

Integrating carbon-halogen bond formation into medicinal plant metabolism.

scientific article published on 3 November 2010

Knockout of pde gene in Arthrobacter sp. CGMCC 3584 and transcriptomic analysis of its effects on cAMP production

scientific article published on 10 January 2020

Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines

scientific article published on 07 December 2020

Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation.

scientific article

Rational engineering acyltransferase domain of modular polyketide synthase for expanding substrate specificity

scientific article published on 12 March 2019

Stabilization of Multimeric Proteins via Intersubunit Cyclization.

scientific article

Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin.

scientific article published on 14 March 2018

ThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequences

scientific article

Transcriptome mining of active biosynthetic pathways and their associated products in Streptomyces flaveolus

scientific article

Uncovering the formation and selection of benzylmalonyl-CoA from the biosynthesis of splenocin and enterocin reveals a versatile way to introduce amino acids into polyketide carbon scaffolds

scientific article published on 19 March 2015

Unravelling the Biosynthetic Flexibility of UK-2A Enables Enzymatic Synthesis of Its Structural Variants

scientific article published on 25 November 2019

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