Search filters

List of works by Eric Largy

A pyrimidopyrimidine Janus-AT nucleoside with improved base-pairing properties to both A and T within a DNA duplex: the stabilizing effect of a second endocyclic ring nitrogen

scientific article published on 17 January 2014

A streptavidin paramagnetic-particle based competition assay for the evaluation of the optical selectivity of quadruplex nucleic acid fluorescent probes

scientific article

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

scientific article published on 02 August 2011

Asymmetric distyrylpyridinium dyes as red-emitting fluorescent probes for quadruplex DNA.

scientific article published on 4 January 2013

Base-pairing behavior of a carbocyclic Janus-AT nucleoside analogue capable of recognizing A and T within a DNA duplex.

scientific article published on 23 September 2013

Cationic Pentaheteroaryls as Selective G-Quadruplex Ligands by Solvent-Free Microwave-Assisted Synthesis

scientific article published on 20 September 2012

DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions

scientific article published on 01 February 2021

Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures

scientific article

Effects of a halogenated G-quadruplex ligand from the pyridine dicarboxamide series on the terminal sequence of XpYp telomere in HT1080 cells

scientific article

Efficient Suppression of Gene Expression by Targeting 5′-UTR-Based RNA Quadruplexes with Bisquinolinium Compounds

article

Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures

scientific article published on 27 May 2011

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

scientific article

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates

scientific article published in Nature Communications

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases

scientific article published on 01 March 2019

Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity

scientific article published in January 2010

Native Hydrogen/Deuterium Exchange Mass Spectrometry of Structured DNA Oligonucleotides

scientific article published on 26 February 2020

Nucleic acids targeted to drugs: SELEX against a quadruplex ligand

scientific article published on 31 May 2011

Orthogonal liquid chromatography-mass spectrometry methods for the comprehensive characterization of therapeutic glycoproteins, from released glycans to intact protein level.

scientific article

Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches

scientific article published on 18 February 2016

Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability

scientific article published on 01 January 2016

Screening for Quadruplex Binding Ligands: A Game of Chance?

Screening of a chemical library by HT-G4-FID for discovery of selective G-quadruplex binders

scientific article

Tridentate N-Donor Palladium(II) Complexes as Efficient Coordinating Quadruplex DNA Binders

scientific article published on 18 October 2011

Unexpected Position-Dependent Effects of Ribose G-Quartets in G-Quadruplexes.

scientific article published on 19 May 2017

Visualizing the quadruplex: from fluorescent ligands to light-up probes

scientific article published on January 2013

Paulina is supported by:

About Paulina

Help