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List of works by Tuan Zea Tan

A central role for TRPS1 in the control of cell cycle and cancer development

scientific article

A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

scientific article published on 25 March 2020

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).

scientific article

Author Correction: Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 07 September 2020

Author Correction: Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 06 November 2020

Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

scientific article published on 08 November 2019

Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma

scientific article published on 22 March 2019

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity

scientific article published on 15 July 2020

Correction: Sundararajan, V., et al. SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2. <i>Cancers</i> 2020, <i>12</i>, 1140

scientific article published on 15 December 2020

Decoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancer

scientific article published on 18 December 2018

Detection of aneuploidy from single fetal nucleated red blood cells using whole genome sequencing

scientific article published on 16 October 2014

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.

scientific article published on 24 July 2014

Dual role of autophagy in hallmarks of cancer.

scientific article published on 19 December 2017

EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway.

scientific article

Epithelial to mesenchymal transition is a cause of both intrinsic and acquired resistance to KRAS G12C inhibitor in KRAS G12C mutant non-small cell lung cancer

scientific article published on 08 September 2020

Epithelial-mesenchymal status renders differential responses to cisplatin in ovarian cancer.

scientific article

Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.

scientific article

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

scientific article published on 22 February 2013

FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.

scientific article

Inflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cells

scientific article published on 24 March 2020

Integrative Analysis and Machine Learning based Characterization of Single Circulating Tumor Cells

scientific article published on 22 April 2020

Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.

scientific article

Molecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clusters

scientific article published in 2014

Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemia

scientific article published on 10 October 2018

Non-invasive prenatal diagnostic testing for β-thalassaemia using cell-free fetal DNA and next generation sequencing.

scientific article published on 29 December 2014

Osteopontin (OPN/SPP1), a Mediator of Tumor Progression, Is Regulated by the Mesenchymal Transcription Factor Slug/SNAI2 in Colorectal Cancer (CRC)

scientific article published on 31 May 2022

Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK ⬇️

scientific article published on 09 December 2019

Phosphatase of regenerating liver-3 is regulated by signal transducer and activator of transcription 3 in acute myeloid leukemia

scientific article published on 17 August 2014

Raf kinase inhibitory protein role in the molecular subtyping of breast cancer

scientific article published on March 2014

SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition.

scientific article published on 5 June 2019

SNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2

scientific article published on 02 May 2020

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

scientific article published on 06 August 2020

Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression.

scientific article

Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

scientific article published on 29 April 2020

The role of GRHL2 and epigenetic remodeling in epithelial-mesenchymal plasticity in ovarian cancer cells

scientific article published on 24 July 2019

The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer

scientific article published on 15 June 2018

USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7

scientific article published on 20 December 2019

Utilization of the Eμ-Myc mouse to model heterogeneity of therapeutic response

scientific article

c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

scientific article published on 25 September 2019

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