List of works - Erik Martens

"Reverse degradomics", monitoring of proteolytic trimming by multi-CE and confocal detection of fluorescent substrates and reaction products

scientific article published in July 2009

A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains

scientific article published on 26 October 2006

Beta-hematin interaction with the hemopexin domain of gelatinase B/MMP-9 provokes autocatalytic processing of the propeptide, thereby priming activation by MMP-3.

scientific article published on February 2008

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines

scientific article published in April 2008

Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma

scientific article published on 01 October 1996

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.

scientific article

Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.

scientific article

Cross-linking approach to affinity capture of protein complexes from chaotrope-solubilized cell lysates.

scientific article published on January 2004

Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease

scientific article published on 03 March 2011

Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels

scientific article published on 18 December 2015

Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study

scientific article

EDTA/gelatin zymography method to identify C1s versus activated MMP-9 in plasma and immune complexes of patients with systemic lupus erythematosus

article

Endotoxemia shifts neutrophils with TIMP-free gelatinase B/MMP-9 from bone marrow to the periphery and induces systematic upregulation of TIMP-1.

scientific article published on 3 August 2017

Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy

scientific article

Gelatinase B is diabetogenic in acute and chronic pancreatitis by cleaving insulin.

scientific article published on 5 March 2003

Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis

scientific article published on 17 May 2016

Glycosaminoglycan mimicry by COAM reduces melanoma growth through chemokine induction and function.

scientific article

GroEL/ES chaperonins protect interferon-gamma against physicochemical stress--study of tertiary structure formation by alpha-casein quenching and ELISA.

scientific article

Highly Selective and Tunable Protein Hydrolysis by a Polyoxometalate Complex in Surfactant Solutions: A Step toward the Development of Artificial Metalloproteases for Membrane Proteins

scientific article published on 11 May 2017

Improved methods for haemozoin quantification in tissues yield organ-and parasite-specific information in malaria-infected mice.

scientific article published on 14 May 2012

Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice

scientific article (publication date: 2011)

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

scientific article

Interphotoreceptor retinoid-binding protein as biomarker in systemic autoimmunity with eye inflictions

scientific article published on 4 February 2008

Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3

scientific article

Multi-chaperone complexes regulate the folding of interferon-gamma in the endoplasmic reticulum.

scientific article

Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates

scientific article published on 12 May 2009

Myeloid cells are tunable by a polyanionic polysaccharide derivative and co-determine host rescue from lethal virus infection.

scientific article published on 13 August 2010

Oligosaccharides of recombinant mouse gelatinase B variants

scientific article published on 01 November 1998

Opposing effects of cyclosporin A and anti-interferon-gamma antibodies on immune tolerance mechanisms

scientific article published on 01 February 1997

Protein disulfide isomerase-mediated cell-free assembly of recombinant interleukin-12 p40 homodimers.

scientific article published in November 2000

Remnant epitopes, autoimmunity and glycosylation.

scientific article

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

scientific article published on 24 April 2020

Side-by-side secretion of Late Palaeozoic diverged courtship pheromones in an aquatic salamander

scientific article

Structural immuno-analysis of human and porcine interferon gamma: identification of shared antigenic domain

scientific article published on 01 August 1997

The Biological Potential Hidden in Inclusion Bodies

scientific article published on 15 February 2020

The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage

scientific article published on 27 April 2006

The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.

scientific article

Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B.

scientific article published on 19 July 2016

Zymography methods for visualizing hydrolytic enzymes.

scientific article

List of works by Erik Martens

"Reverse degradomics", monitoring of proteolytic trimming by multi-CE and confocal detection of fluorescent substrates and reaction products

A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains

Beta-hematin interaction with the hemopexin domain of gelatinase B/MMP-9 provokes autocatalytic processing of the propeptide, thereby priming activation by MMP-3.

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines

Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma

Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1.

Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis.

Cross-linking approach to affinity capture of protein complexes from chaotrope-solubilized cell lysates.

Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease

Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels

Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study

EDTA/gelatin zymography method to identify C1s versus activated MMP-9 in plasma and immune complexes of patients with systemic lupus erythematosus

Endotoxemia shifts neutrophils with TIMP-free gelatinase B/MMP-9 from bone marrow to the periphery and induces systematic upregulation of TIMP-1.

Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy

Gelatinase B is diabetogenic in acute and chronic pancreatitis by cleaving insulin.

Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis

Glycosaminoglycan mimicry by COAM reduces melanoma growth through chemokine induction and function.

GroEL/ES chaperonins protect interferon-gamma against physicochemical stress--study of tertiary structure formation by alpha-casein quenching and ELISA.

Highly Selective and Tunable Protein Hydrolysis by a Polyoxometalate Complex in Surfactant Solutions: A Step toward the Development of Artificial Metalloproteases for Membrane Proteins

Improved methods for haemozoin quantification in tissues yield organ-and parasite-specific information in malaria-infected mice.

Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice

Interference with glycosaminoglycan-chemokine interactions with a probe to alter leukocyte recruitment and inflammation in vivo.

Interphotoreceptor retinoid-binding protein as biomarker in systemic autoimmunity with eye inflictions

Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3

Multi-chaperone complexes regulate the folding of interferon-gamma in the endoplasmic reticulum.

Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates

Myeloid cells are tunable by a polyanionic polysaccharide derivative and co-determine host rescue from lethal virus infection.

Oligosaccharides of recombinant mouse gelatinase B variants

Opposing effects of cyclosporin A and anti-interferon-gamma antibodies on immune tolerance mechanisms

Protein disulfide isomerase-mediated cell-free assembly of recombinant interleukin-12 p40 homodimers.

Remnant epitopes, autoimmunity and glycosylation.

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

Side-by-side secretion of Late Palaeozoic diverged courtship pheromones in an aquatic salamander

Structural immuno-analysis of human and porcine interferon gamma: identification of shared antigenic domain

The Biological Potential Hidden in Inclusion Bodies

The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage

The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.

Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B.

Zymography methods for visualizing hydrolytic enzymes.