List of works - Daniel De Carvalho

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

scientific article published on 01 August 2020

Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

scientific article published on 07 September 2020

BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy

scientific article published on 12 October 2017

BCR–ABL-mediated upregulation of PRAME is responsible for knocking down TRAIL in CML patients ⬇️

scientific article published on September 13, 2010

Constitutive androstane receptor ligands modulate the anti-tumor efficacy of paclitaxel in non-small cell lung cancer cells

scientific article

DNA methylation and cellular reprogramming

scientific article

DNA methylation screening identifies driver epigenetic events of cancer cell survival

scientific article

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

scientific article published on August 2015

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes

scientific article published on 22 June 2020

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

scientific article published on 22 June 2020

Drug-induced activation of "junk" DNA - A path to combat cancer therapy resistance?

scientific article

Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation.

scientific article

Epigenetic modifications as therapeutic targets ⬇️

scientific article published on October 1, 2010

Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage

scientific article published on 02 February 2017

Epigenetic therapy in immune-oncology

scientific article published on 01 March 2019

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency

scientific article published on 21 October 2020

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

scientific article published on 01 December 2019

High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis.

scientific article

IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment

scientific article

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

scientific article

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

scientific article published in 2024

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.

scientific article published on 9 July 2016

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance

scientific article

O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection.

scientific article published on 20 September 2017

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

scientific article

Pharmacological DNA demethylation: Implications for cancer immunotherapy.

scientific article

Polycomb-repressed genes have permissive enhancers that initiate reprogramming

scientific article published on December 2011

Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation.

scientific article published on 19 February 2016

Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA

scientific article published on 30 August 2019

SNF5 is an essential executor of epigenetic regulation during differentiation.

scientific article

Symmetrical Dose-Dependent DNA-Methylation Profiles in Children with Deletion or Duplication of 7q11.23

scientific article

TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure

scientific article published in Nature Communications

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

scientific article published on 29 March 2019

The Cancer Epigenome: Exploiting Its Vulnerabilities for Immunotherapy

scientific article published on 25 August 2018

The cell wall fraction from Fonsecaea pedrosoi stimulates production of different profiles of cytokines and nitric oxide by murine peritoneal cells in vitro.

scientific article published on 30 March 2010

List of works by Daniel De Carvalho

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy

BCR–ABL-mediated upregulation of PRAME is responsible for knocking down TRAIL in CML patients ⬇️

Constitutive androstane receptor ligands modulate the anti-tumor efficacy of paclitaxel in non-small cell lung cancer cells

DNA methylation and cellular reprogramming

DNA methylation screening identifies driver epigenetic events of cancer cell survival

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

Drug-induced activation of "junk" DNA - A path to combat cancer therapy resistance?

Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation.

Epigenetic modifications as therapeutic targets ⬇️

Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage

Epigenetic therapy in immune-oncology

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency

GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment

High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis.

IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.

Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance

O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection.

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

Pharmacological DNA demethylation: Implications for cancer immunotherapy.

Polycomb-repressed genes have permissive enhancers that initiate reprogramming

Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation.

Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA

SNF5 is an essential executor of epigenetic regulation during differentiation.

Symmetrical Dose-Dependent DNA-Methylation Profiles in Children with Deletion or Duplication of 7q11.23

TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

The Cancer Epigenome: Exploiting Its Vulnerabilities for Immunotherapy

The cell wall fraction from Fonsecaea pedrosoi stimulates production of different profiles of cytokines and nitric oxide by murine peritoneal cells in vitro.