List of works - Barbara Cassani

Anti-CD3ε mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications

scientific article published on 21 June 2012

Bone marrow clonogenic capability, cytokine production, and thymic output in patients with common variable immunodeficiency.

scientific article published in April 2005

Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene

scientific article

Defect of regulatory T cells in patients with Omenn syndrome

scientific article published on 01 January 2010

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

scientific article

Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice

scientific article published on 16 September 2011

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

scientific article

Hot spots of retroviral integration in human CD34+ hematopoietic cells

scientific article

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

scientific article

Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.

scientific article published on 19 September 2013

IL-10 critically modulates B cell responsiveness in Rankl-/- mice.

scientific article published on 30 March 2015

In vivo T-cell dynamics during immune reconstitution after hematopoietic stem cell gene therapy in adenosine deaminase severe combined immune deficiency ⬇️

scientific article published on April 7, 2011

Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy

scientific article published on 23 August 2011

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

scientific article

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects

scientific article

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients

scientific article

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

scientific article published in August 2007

Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO.

scientific article

RANK-dependent autosomal recessive osteopetrosis: characterization of five new cases with novel mutations

scientific article published in February 2012

Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome

scientific article published on 9 December 2013

Reply: To PMID 24332219.

scientific article published on 26 June 2014

Vitamin A and immune regulation: role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance

scientific article

β7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential.

scientific article

List of works by Barbara Cassani

Anti-CD3ε mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications

Bone marrow clonogenic capability, cytokine production, and thymic output in patients with common variable immunodeficiency.

Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene

Defect of regulatory T cells in patients with Omenn syndrome

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Hot spots of retroviral integration in human CD34+ hematopoietic cells

Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations

Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.

IL-10 critically modulates B cell responsiveness in Rankl-/- mice.

In vivo T-cell dynamics during immune reconstitution after hematopoietic stem cell gene therapy in adenosine deaminase severe combined immune deficiency ⬇️

Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy

Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy.

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO.

RANK-dependent autosomal recessive osteopetrosis: characterization of five new cases with novel mutations

Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome

Reply: To PMID 24332219.

Vitamin A and immune regulation: role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance

β7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential.