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List of works by Aaron T Irving

ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton.

scientific article published on 27 March 2013

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.

scientific article

Animal and translational models of SARS-CoV-2 infection and COVID-19

scientific article published on 20 August 2020

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.

scientific article

Complementary regulation of caspase-1 and IL-1β reveals additional mechanisms of dampened inflammation in bats

scientific article published on 26 October 2020

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host

scientific article published on 25 February 2019

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

scientific article published on 26 April 2021

Exploring the genome and transcriptome of the cave nectar bat Eonycteris spelaea with PacBio long-read sequencing

scientific article published on 01 October 2018

Genetic modulation of TLR8 response following bacterial phagocytosis.

scientific article published on September 2010

High basal heat-shock protein expression in bats confers resistance to cellular heat/oxidative stress

scientific article published on 22 June 2019

High-resolution aging niche of human adipose tissues

scientific article published in 2023

IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection.

scientific article

Latest advances in innate antiviral defence.

scientific article published on March 2009

Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.

scientific article published on 17 November 2014

Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto.

scientific article

Rational design of immunostimulatory siRNAs.

scientific article

Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense ⬇️

scientific article published on May 25, 2012

Robust dengue virus infection in bat cells and limited innate immune responses coupled with positive serology from bats in IndoMalaya and Australasia

scientific article published on 27 July 2019

Studies on B Cells in the Fruit-Eating Black Flying Fox (

scientific article published on 14 March 2019

Sustained Low-Dose Treatment with the Histone Deacetylase Inhibitor LBH589 Induces Terminal Differentiation of Osteosarcoma Cells

scientific article published on 28 February 2013

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.

scientific article published on 13 April 2015

The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling

scientific article published on 17 April 2014

Unique Loss of the PYHIN Gene Family in Bats Amongst Mammals: Implications for Inflammasome Sensing

scientific article

Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages.

scientific article published on 09 December 2016

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