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List of works by Phillip P. Sharp

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

scientific article

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

BET bromodomain inhibitors: a patent review

scientific article

BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells.

scientific article published on 08 March 2016

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

scientific article published on 6 May 2015

CIS is a potent checkpoint in NK cell-mediated tumor immunity

scientific article

Consecutive gold(I)-catalyzed cyclization reactions of o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas: a one-pot synthesis of pyrimido[1,6-a]indol-1(2H)-ones and related systems

scientific article published on 21 May 2013

Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors

scientific article published on 14 November 2017

Histone H3K27ac separates active from poised enhancers and predicts developmental state

scientific article

Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

scientific article

Simplified silvestrol analogues with potent cytotoxic activity.

scientific article published on 27 March 2014

Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments

scientific article published on 07 March 2017

Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P.

scientific article published on 12 December 2016

Total Syntheses of the 3H-Pyrrolo[2,3-c]quinolone-Containing Alkaloids Marinoquinolines A-F, K, and Aplidiopsamine A Using a Palladium-Catalyzed Ullmann Cross-Coupling/Reductive Cyclization Pathway

scientific article published on 18 December 2019

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