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List of works by Konstantinos Tzelepis

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

scientific article

Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML

scientific article published on 16 March 2020

Effect of BRCA1 immunohistochemical localizations on prognosis of patients with sporadic breast carcinomas.

scientific article

Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

scientific article

Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition

scientific article published on 20 February 2018

Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts.

scientific article published on 08 September 2016

KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements

scientific article published on 06 August 2020

Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia

scientific article published on 23 August 2017

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

scientific article published on 06 September 2018

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.

scientific article published on 27 November 2017

RNA modifications detection by comparative Nanopore direct RNA sequencing

scientific article published on 10 December 2021

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

scientific article published in Nature Communications

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs

scientific article published on 07 May 2018

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