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List of works by Virginie Penard-Lacronique

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

scientific article

A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.

scientific article published on 28 July 2016

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.

scientific article published on 13 February 2017

Activating mutations in human acute megakaryoblastic leukemia.

scientific article

Activation of the NF-kappaB pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKKalpha.

scientific article published on 23 January 2006

Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model

scientific article

Azathioprine-induced carcinogenesis in mice according to Msh2 genotype

scientific article published on 5 October 2010

Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib

scientific article published on 16 July 2018

Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis

scientific article published on 02 October 2019

Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers.

scientific article

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.

scientific article published on 19 January 2018

Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

scientific article published on 06 June 2017

Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis

scientific article

Familial hematological malignancies: new IDH2 mutation.

scientific article published on 3 September 2016

Functional analysis of the NUP98-CCDC28A fusion protein

scientific article published on 4 November 2011

Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

scholarly article

HOX11L2/TLX3 is transcriptionally activated through T-cell regulatory elements downstream of BCL11B as a result of the t(5;14)(q35;q32)

scientific article published on 22 August 2006

IDH1, Histone Methylation, and So Forth

scientific article published on 12 September 2016

IDH1, Histone Methylation, and So Forth.

scientific article published in August 2016

Identification of GSX2 and AF10 as NUP98 partner genes in myeloid malignancies

scientific article published on 12 July 2013

Isocitrate dehydrogenase (IDH)2 R140Q mutation induces myeloid and lymphoid neoplasms in mice

scientific article published on 14 January 2014

Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

scientific article published on 26 February 2018

NUP98-MLL fusion in human acute myeloblastic leukemia.

scientific article published on 17 June 2010

NUP98–HMGB3: a novel oncogenic fusion

scientific article published on 03 December 2009

Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia.

scientific article published on 26 October 2006

Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications

scientific article published on 23 April 2016

Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression

scientific article

SRF selectively controls tip cell invasive behavior in angiogenesis.

scientific article published in June 2013

Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells.

scientific article published on 14 September 2017

Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.

scientific article

Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation

scientific article

The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation.

scientific article published on 4 September 2006

The serum response factor (SRF)/megakaryocytic acute leukemia (MAL) network participates in megakaryocyte development

scientific article published on 29 April 2010

The transcription factor Srf regulates hematopoietic stem cell adhesion

scientific journal article

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