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List of works by Alain Lacampagne

AMPK activation stimulates autophagy and ameliorates muscular dystrophy in the mdx mouse diaphragm.

scientific article

ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.

scientific article published on 23 May 2008

Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human

scientific article

Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries

scientific article

Altered myofilament structure and function in dogs with Duchenne muscular dystrophy cardiomyopathy

scientific article published on 21 December 2017

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

scientific article

Andersen's syndrome mutants produce a knockdown of inwardly rectifying K+ channel in mouse skeletal muscle in vivo.

scientific article published on 10 October 2017

Antagonism of Nav channels and α1-adrenergic receptors contributes to vascular smooth muscle effects of ranolazine.

scientific article

Anti-inflammatory drugs as promising cardiovascular treatments.

scientific article published on 23 December 2016

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure.

scientific article published on 17 May 2014

Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing

scientific article

Beneficial effects of SR33805 in failing myocardium.

scientific article

Blebbistatin: use as inhibitor of muscle contraction.

scientific article published on 10 November 2007

Bradykinin restores left ventricular function, sarcomeric protein phosphorylation, and e/nNOS levels in dogs with Duchenne muscular dystrophy cardiomyopathy ⬇️

scientific article published on May 4, 2012

Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure?

scientific article published on 3 August 2005

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

scientific article

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

scientific article

Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress.

scientific article

Carbon monoxide pollution aggravates ischemic heart failure through oxidative stress pathway.

scientific article published on 03 January 2017

Carnitine deficiency induces a short QT syndrome.

scientific article published on 17 July 2015

Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function

scientific article

Chronic clenbuterol treatment compromises force production without directly altering skeletal muscle contractile machinery

scientific article published on 27 February 2015

Consequences of mechanical ventilation on diaphragmatic function

scientific article published on 6 November 2014

Critical Role for Stromal Interaction Molecule 1 in Cardiac Hypertrophy ⬇️

scientific article published on August 16, 2011

Defects in ryanodine receptor calcium release in skeletal muscle from post-myocardial infarct rats.

scientific article

Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury.

scientific article published on 27 August 2013

Differential localization of autolyzed calpains 1 and 2 in slow and fast skeletal muscles in the early phase of atrophy

scientific journal article

Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.

scientific article published on 10 December 2015

Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress

scientific article published on 15 January 2019

ER stress disturbs SR/ER-mitochondria Ca2+ transfer: Implications in Duchenne muscular dystrophy.

scientific article published on 15 June 2017

Effect of a high dose of simvastatin on muscle mitochondrial metabolism and calcium signaling in healthy volunteers ⬇️

scientific article published on July 4, 2012

Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice.

scientific article published on 14 June 2017

Effect of ryanodine on cardiac calcium current and calcium channel gating current.

scientific article published on January 1996

Effects of chronic administration of clenbuterol on contractile properties and calcium homeostasis in rat extensor digitorum longus muscle

scientific article

Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart.

scientific article

Effects of high-altitude exercise training on contractile function of rat skinned cardiomyocyte

scientific article published on 21 June 2006

Effects of intermittent femoral nerve injections of bupivacaine, levobupivacaine, and ropivacaine on mitochondrial energy metabolism and intracellular calcium homeostasis in rat psoas muscle

scientific article published in May 2007

Emergence of Orai3 activity during cardiac hypertrophy.

scientific article published on 11 September 2014

Fem1a is a mitochondrial protein up-regulated upon ischemia-reperfusion injury.

scientific article published on 4 May 2009

Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells.

scientific article published on 21 November 2013

Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells.

scientific article

Functional evidence for an active role of B-type natriuretic peptide in cardiac remodelling and pro-arrhythmogenicity.

scientific article published on 22 May 2012

Hidden face of the anterior pituitary.

scientific article

Human pluripotent stem cell-derived cardiomyocytes as research and therapeutic tools.

scientific article published on 2 April 2014

Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model.

scientific article

Interest of colchicine in the treatment of acute myocardial infarct responsible for heart failure in a mouse model

scientific article published in April 2017

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning.

scientific article published on 12 October 2015

Key role of endothelium in the eNOS-dependent cardioprotection with exercise training.

scientific article

Late exercise training improves non-uniformity of transmural myocardial function in rats with ischaemic heart failure

scientific article published on 14 August 2008

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

scientific article

Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation

scientific article published on 25 July 2016

Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.

scientific article published on 08 July 2016

Modulation of the Frequency of Spontaneous Sarcoplasmic Reticulum Ca2+ Release Events (Ca2+ Sparks) by Myoplasmic [Mg2+] in Frog Skeletal Muscle ⬇️

scientific article published on February 1, 1998

Muscle mitochondrial metabolism and calcium signaling impairment in patients treated with statins

scientific article published on 17 January 2012

Neuregulin 1 improves glucose tolerance in adult and old rats.

scientific article

New drug avenues for cardioprotection in patients with acute myocardial infarction

scientific article published on 01 February 2014

Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid.

scientific article published on 21 April 2015

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise

scientific article published on June 2016

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise

scientific article published on 01 January 2017

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

scientific article

Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

scientific article published on 23 January 2015

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits

scientific article published on 19 June 2017

Rapid onset of specific diaphragm weakness in a healthy murine model of ventilator-induced diaphragmatic dysfunction

scientific article published on September 2012

Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans

scientific article published on 02 September 2010

Regional variation in myofilament length-dependent activation ⬇️

scientific article published on February 19, 2011

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

scientific article published on 16 November 2011

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity

scientific article

Reply concerning "Colchicine in coronary artery disease: Role of anti-inflammatory medications redefined": Prime time for anti-inflammatory agents for the management of cardiovascular diseases

scientific article published on 28 January 2018

Repriming and activation alter the frequency of stereotyped discrete Ca2+ release events in frog skeletal muscle.

scientific article published on December 1996

Respiratory muscle contractile inactivity induced by mechanical ventilation in piglets leads to leaky ryanodine receptors and diaphragm weakness

scientific article published on 4 March 2017

Revealing the large-scale network organization of growth hormone-secreting cells.

scientific article

Ryanodine receptor and heart disease

scientific article published in April 2008

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

scientific journal article

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

scientific article published on August 2011

SR33805, a Ca2+ antagonist with length-dependent Ca2+ -sensitizing properties in cardiac myocytes.

scientific article published in May 2003

Sepsis is associated with a preferential diaphragmatic atrophy: a critically ill patient study using tridimensional computed tomography

scientific article published on 01 May 2014

Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.

scientific article published on 25 November 2014

Simvastatin induces impairment in skeletal muscle while heart is protected.

scientific article published on 26 October 2005

Speckle tracking echocardiography in healthy children: comparison between the QLAB by Philips and the EchoPAC by General Electric

scientific article published on 08 January 2019

Speckle-Tracking Echocardiography in Children With Duchenne Muscular Dystrophy: A Prospective Multicenter Controlled Cross-Sectional Study

scientific article published on 21 January 2019

Streptomycin reverses a large stretch induced increases in [Ca2+]i in isolated guinea pig ventricular myocytes

scientific article published on 01 August 1994

Stress-induced protein S-glutathionylation and phosphorylation crosstalk in cardiac sarcomeric proteins - Impact on heart function.

scientific article

Subendocardial increase in reactive oxygen species production affects regional contractile function in ischemic heart failure.

scientific article published on 26 October 2012

TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes

scientific article published on 6 May 2014

Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor

scientific article published on September 2011

The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.

scientific article

Time course of individual Ca2+ sparks in frog skeletal muscle recorded at high time resolution.

scientific article

Triadins are not triad-specific proteins: two new skeletal muscle triadins possibly involved in the architecture of sarcoplasmic reticulum

scientific article published on 31 May 2005

Two mechanisms for termination of individual Ca2+ sparks in skeletal muscle

scientific article published in July 2000

Type 2 ryanodine receptor: a novel therapeutic target in myocardial ischemia/reperfusion.

scientific article published on 04 February 2013

Voltage dependence of the pattern and frequency of discrete Ca2+ release events after brief repriming in frog skeletal muscle.

scientific article published on September 1997

[A 3D cell network which brings out relief in the pituitary gland]

scientific article published on 01 May 2006

p11 modulates calcium handling through 5-HT₄R pathway in rat ventricular cardiomyocytes.

scientific article published on 20 August 2015

β-Adrenergic blockade combined with subcutaneous B-type natriuretic peptide: a promising approach to reduce ventricular arrhythmia in heart failure?

scientific article published on 25 March 2014

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