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List of works by Craig MacLean

A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria.

scientific article published on 27 February 2013

Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms

scientific article published on 12 December 2017

CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa

scientific article published on 21 December 2020

Comparative analysis of myxococcus predation on soil bacteria.

scientific article published on 27 August 2010

Compensatory mutations modulate the competitiveness and dynamics of plasmid-mediated colistin resistance in Escherichia coli clones

scientific article published on 02 January 2020

Constraints on microbial metabolism drive evolutionary diversification in homogeneous environments.

scientific article

Cooperation, competition and antibiotic resistance in bacterial colonies

article

Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa ⬇️

scientific article published on September 27, 2010

Dispersal scales up the biodiversity-productivity relationship in an experimental source-sink metacommunity.

scientific article published on 24 March 2010

Divergent evolution during an experimental adaptive radiation

scientific article published on 01 August 2003

Divergent evolution peaks under intermediate population bottlenecks during bacterial experimental evolution.

scientific article published in July 2016

Diversity and productivity peak at intermediate dispersal rate in evolving metacommunities.

scientific article

Ecological genetics: the decline and fall of a metabolic pathway in yeast.

scientific article published in March 2005

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

scientific article published on 07 August 2020

Environmental variation alters the fitness effects of rifampicin resistance mutations in Pseudomonas aeruginosa.

scientific article published on 2 March 2016

Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas.

scientific article

Epistasis buffers the fitness effects of rifampicin-resistance mutations in Pseudomonas aeruginosa

scientific article published on 22 April 2016

Epistatic interactions between ancestral genotype and beneficial mutations shape evolvability in Pseudomonas aeruginosa.

scientific article published on 15 June 2016

Erratum

Evaluating evolutionary models of stress-induced mutagenesis in bacteria

scientific article published on 12 February 2013

Evaluating the effect of horizontal transmission on the stability of plasmids under different selection regimes

scientific article published on 21 May 2015

Evolutionary reversals of antibiotic resistance in experimental populations of Pseudomonas aeruginosa.

scientific article published on 5 June 2013

Experimental adaptive radiation in Pseudomonas

scientific article published on 01 November 2002

Experimental evolution of Pseudomonas fluorescens in simple and complex environments.

scientific article published on 5 August 2005

Fitness Costs of Plasmids: a Limit to Plasmid Transmission

scientific article published in September 2017

Fitness is strongly influenced by rare mutations of large effect in a microbial mutation accumulation experiment

scientific article

Here's to the losers: evolvable residents accelerate the evolution of high-fitness invaders.

scientific article published on 12 May 2015

Identification of Acanthamoeba sp. in paraffin-embedded CNS tissue from an HIV+ individual by PCR.

scientific article

Identifying and exploiting genes that potentiate the evolution of antibiotic resistance

article

Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1

scientific article published on 10 August 2018

Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa

scientific article

Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria

scientific article

Linking system-wide impacts of RNA polymerase mutations to the fitness cost of rifampin resistance in Pseudomonas aeruginosa

scientific article published on 9 December 2014

Microbial Evolution: Towards Resolving the Plasmid Paradox.

scientific article

Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation

scientific article published on 09 April 2018

Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria.

scientific article

Mutational neighbourhood and mutation supply rate constrain adaptation in Pseudomonas aeruginosa

scientific article published on 04 November 2009

Parasite diversity drives rapid host dynamics and evolution of resistance in a bacteria-phage system

scientific article published on 23 March 2016

Persistence and resistance as complementary bacterial adaptations to antibiotics.

scientific article

Pleiotropy and GAL pathway degeneration in yeast

scientific article published on 01 July 2007

Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations.

scientific article

Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids.

scientific article

Predicting epistasis: an experimental test of metabolic control theory with bacterial transcription and translation

scientific article published on 07 January 2010

Sequencing of plasmids pAMBL1 and pAMBL2 from Pseudomonas aeruginosa reveals a blaVIM-1 amplification causing high-level carbapenem resistance

scientific article published on 24 July 2015

Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells

scientific article published on 23 July 2020

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

scientific article published on 02 May 2018

Testing the role of genetic background in parallel evolution using the comparative experimental evolution of antibiotic resistance.

scientific article published on 16 September 2014

The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa.

scientific article

The SOS response increases bacterial fitness, but not evolvability, under a sublethal dose of antibiotic.

scientific article

The cost of copy number in a selfish genetic element: the 2-μm plasmid of Saccharomyces cerevisiae.

scientific article published on 19 September 2012

The cost of multiple drug resistance in Pseudomonas aeruginosa.

scientific article published on 27 February 2009

The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa

scientific article

The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens.

scientific article

The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach

scientific article published on 12 December 2014

The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa.

scientific article

The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts.

scientific article published on June 2010

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