List of works - Daniela Arosio

4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents

scientific article published on 13 April 2017

A new optical imaging probe targeting αVβ3 integrin in glioblastoma xenografts.

scientific article

A potent integrin antagonist from a small library of cyclic RGD pentapeptide mimics including benzyl-substituted azabicycloalkane amino acids

scientific article

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

scientific article published on March 2015

Conjugates of Cryptophycin and RGD or isoDGR Peptidomimetics for Targeted Drug Delivery

scientific article published on 07 June 2019

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

Cyclic RGD and isoDGR Integrin Ligands Containing cis-2-amino-1-cyclopentanecarboxylic (cis-β-ACPC) Scaffolds

scientific article published on 16 December 2020

Cyclic RGD-containing functionalized azabicycloalkane peptides as potent integrin antagonists for tumor targeting.

scientific article published in April 2009

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

scientific article

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

scientific article published on 19 February 2013

Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD-paclitaxel conjugates for integrin-assisted drug delivery

scientific article published on July 2015

Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.

scientific article

Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents

scientific article published on 22 August 2016

Effective targeting of DC-SIGN by α-fucosylamide functionalized gold nanoparticles.

scientific article

Enhancement of the uptake and cytotoxic activity of doxorubicin in cancer cells by novel cRGD-semipeptide-anchoring liposomes.

scientific article published on 22 May 2014

Functionalized azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition.

scientific article published in May 2005

Functionalized cyclic RGD peptidomimetics: conjugable ligands for αvβ3 receptor imaging.

scientific article

Ganglioside GM1 mimics: lipophilic substituents improve affinity for cholera toxin.

scientific article published in November 2003

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

scientific article

Integrin-Targeted Peptide- and Peptidomimetic-Drug Conjugates for the Treatment of Tumors

scientific article published on 3 February 2017

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

scientific article published on 21 September 2017

MicroPET/CT imaging of αvβ₃ integrin via a novel ⁶⁸Ga-NOTA-RGD peptidomimetic conjugate in rat myocardial infarction.

scientific article published on 15 May 2013

Mimics of ganglioside GM1 as cholera toxin ligands: replacement of the GalNAc residue.

scientific article published in March 2003

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

scientific article published on 17 August 2017

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

scientific article published on 27 December 2018

New potent αvβ3 integrin ligands based on azabicycloalkane (γ,α)-dipeptide mimics

scientific article published on 26 February 2016

Stereoselective synthesis of conformationally constrained cyclohexanediols: a set of molecular scaffolds for the synthesis of glycomimetics.

scientific article published in September 2001

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

scientific article published on 22 March 2019

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

scientific article

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

scientific article

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

scientific article published on 16 April 2014

Synthesis and cholera toxin binding properties of multivalent GM1 mimics

scientific article published on 30 June 2004

Synthesis of Gd and (68)Ga complexes in conjugation with a conformationally optimized RGD sequence as potential MRI and PET tumor-imaging probes.

scientific article

Synthesis of Novel c(AmpRGD)-Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis

scientific article published on 20 December 2016

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

scientific article

Tumor Targeting with an isoDGR-Drug Conjugate

scientific article published on 27 April 2017

List of works by Daniela Arosio

4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents

A new optical imaging probe targeting αVβ3 integrin in glioblastoma xenografts.

A potent integrin antagonist from a small library of cyclic RGD pentapeptide mimics including benzyl-substituted azabicycloalkane amino acids

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

Conjugates of Cryptophycin and RGD or isoDGR Peptidomimetics for Targeted Drug Delivery

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

Cyclic RGD and <i>iso</i>DGR Integrin Ligands Containing <i>cis</i>-2-amino-1-cyclopentanecarboxylic (<i>cis</i>-β-ACPC) Scaffolds

Cyclic RGD-containing functionalized azabicycloalkane peptides as potent integrin antagonists for tumor targeting.

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD-paclitaxel conjugates for integrin-assisted drug delivery

Design, synthesis, and biological evaluation of novel cRGD-paclitaxel conjugates for integrin-assisted drug delivery.

Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents

Effective targeting of DC-SIGN by α-fucosylamide functionalized gold nanoparticles.

Enhancement of the uptake and cytotoxic activity of doxorubicin in cancer cells by novel cRGD-semipeptide-anchoring liposomes.

Functionalized azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition.

Functionalized cyclic RGD peptidomimetics: conjugable ligands for αvβ3 receptor imaging.

Ganglioside GM1 mimics: lipophilic substituents improve affinity for cholera toxin.

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

Integrin-Targeted Peptide- and Peptidomimetic-Drug Conjugates for the Treatment of Tumors

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

MicroPET/CT imaging of αvβ₃ integrin via a novel ⁶⁸Ga-NOTA-RGD peptidomimetic conjugate in rat myocardial infarction.

Mimics of ganglioside GM1 as cholera toxin ligands: replacement of the GalNAc residue.

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

New potent αvβ3 integrin ligands based on azabicycloalkane (γ,α)-dipeptide mimics

Stereoselective synthesis of conformationally constrained cyclohexanediols: a set of molecular scaffolds for the synthesis of glycomimetics.

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

Synthesis and cholera toxin binding properties of multivalent GM1 mimics

Synthesis of Gd and (68)Ga complexes in conjugation with a conformationally optimized RGD sequence as potential MRI and PET tumor-imaging probes.

Synthesis of Novel c(AmpRGD)-Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

Tumor Targeting with an isoDGR-Drug Conjugate