List of works - Gordon J Florence

1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide

scientific article published on 01 January 2003

A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.

scientific article published on 22 January 2004

An internal thioester in a pathogen surface protein mediates covalent host binding

scientific article published on 2 June 2015

Approaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis

scientific article published on 25 June 2019

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

scientific article published on 9 January 2018

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors

scientific article published on 10 June 2016

Discodermolide interferes with the binding of tau protein to microtubules.

scientific article published in March 2003

Intraluminal magnetisation of bowel by ferromagnetic particles for retraction and manipulation by magnetic probes

scientific article published on 26 August 2014

Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase

scientific article published on 16 January 2017

Magnetic retraction of bowel by intraluminal injectable cyanoacrylate-based magnetic glue.

scientific article

Mucoadhesive polymer films for tissue retraction in laparoscopic surgery: Ex-vivo study on their mechanical properties

scientific article published in January 2014

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

scientific article

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

scientific article published on 5 September 2017

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins

scientific article published on 28 January 2017

Stereocontrolled Total Synthesis of (-)-Aurisides A and B

scientific article published 2005

Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase

scientific article published on 29 May 2019

Synthesis and Stereochemical Assignment of (+)-Chamuvarinin ⬇️

scientific article published on December 21, 2010

Synthesis of the originally proposed structure of palmerolide C

scientific article published on 02 October 2012

The chemical synthesis of discodermolide

scientific article published on 01 January 2009

The trypanosome alternative oxidase: a potential drug target?

scientific article published on 29 November 2016

Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones

scientific article published on 01 January 2000

Total synthesis and stereochemical reassignment of (+)-dolastatin 19

scientific article published on 01 May 2006

Total synthesis of (-)-reidispongiolide A, an actin-targeting macrolide isolated from the marine sponge Reidispongia coerulea.

scientific article published in February 2008

Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues.

scientific article

List of works by Gordon J Florence

1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide

A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.

An internal thioester in a pathogen surface protein mediates covalent host binding

Approaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors

Discodermolide interferes with the binding of tau protein to microtubules.

Intraluminal magnetisation of bowel by ferromagnetic particles for retraction and manipulation by magnetic probes

Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase

Magnetic retraction of bowel by intraluminal injectable cyanoacrylate-based magnetic glue.

Mucoadhesive polymer films for tissue retraction in laparoscopic surgery: Ex-vivo study on their mechanical properties

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins

Stereocontrolled Total Synthesis of (-)-Aurisides A and B

Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase

Synthesis and Stereochemical Assignment of (+)-Chamuvarinin ⬇️

Synthesis of the originally proposed structure of palmerolide C

The chemical synthesis of discodermolide

The trypanosome alternative oxidase: a potential drug target?

Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones

Total synthesis and stereochemical reassignment of (+)-dolastatin 19

Total synthesis of (-)-reidispongiolide A, an actin-targeting macrolide isolated from the marine sponge Reidispongia coerulea.

Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues.