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List of works by Irina Gazaryan

A novel approach to distinguish between enzyme mechanisms: quasi-steady-state kinetic analysis of the prostaglandin H synthase peroxidase reaction.

scientific article published on June 2003

A screen for inducers of p21waf1/cip1 identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties ⬇️

scientific article published on August 27, 2012

Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.

scientific article

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease

scientific article published on December 2016

Bioelectrochemical monitoring of phenols and aromatic amines in flow injection using novel plant peroxidases.

scientific article published in July 1998

Biosensors based on novel peroxidases with improved properties in direct and mediated electron transfer

scientific article published on 01 January 2000

Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases.

scientific article published on October 2012

Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators ⬇️

scientific article published on June 24, 2011

Direct electrochemistry and bioelectrocatalysis of H2O2 reduction of recombinant tobacco peroxidase on graphite. Effect of peroxidase single-point mutation on Ca2+-modulated catalytic activity

article by John J Castillo et al published March 2006 in Journal of Electroanalytical Chemistry

Direct electrochemistry of recombinant tobacco peroxidase on gold

article by Elena Ferapontova et al published December 2005 in Electrochemistry Communications

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease

scientific article published on June 2016

Enzyme-Substrate Reporters for Evaluation of Substrate Specificity of HIF Prolyl Hydroxylase Isoforms.

scientific article published in October 2017

Glutamic acid-141: a heme 'bodyguard' in anionic tobacco peroxidase.

scientific article published in April 2007

Harnessing hypoxic adaptation to prevent, treat, and repair stroke.

scientific article

High-yield reactivation of anionic tobacco peroxidase overexpressed in Escherichia coli.

scientific article

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.

scientific article published on 31 January 2013

Immobilization of peroxidase glycoprotein on gold electrodes modified with mixed epoxy-boronic Acid monolayers.

scientific article published in October 2002

Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

scientific article published on 28 November 2012

Intersection between mitochondrial permeability pores and mitochondrial fusion/fission.

scientific article published on 7 March 2007

Ion concentration of external solution as a characteristic of micro- and nanogel ionic reservoirs

scientific article published on 01 August 2006

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

scientific article

Non-enzymatic interaction of reaction products and substrates in peroxidase catalysis

scientific article published on September 1, 2003

Novel laccase redox mediators: spectral, electrochemical, and kinetic properties.

scientific article

Oxidation of indole-3-acetic acid by dioxygen catalysed by plant peroxidases: specificity for the enzyme structure.

scientific article published on June 1999

Physicochemical characterization of natural ionic Microreservoirs: Bacillus subtilis dormant spores

scientific article published on 05 February 2008

Recombinant horseradish peroxidase - and cytochrome c-based two-electrode system for detection of superoxide radicals

scientific article published in June 2004

Site-directed mutagenesis of tobacco anionic peroxidase: Effect of additional aromatic amino acids on stability and activity.

scientific article published on 7 May 2015

Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury

scientific article

Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail".

scientific article published on 19 December 2016

The status of Nrf2-based therapeutics: current perspectives and future prospects

scientific article (publication date: November 2016)

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

scientific article published on March 2016

Tryptophanless recombinant horseradish peroxidase: stability and catalytic properties

scientific article published on 01 August 1999

Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition

scientific article published on 12 June 2007

Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.

scientific article published on 13 December 2001

pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification

scientific article (publication date: 22 April 2005)

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