Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Ivanhoe K. H. Leung

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.

scientific article published on 9 March 2018

A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2-chromen-4-ol Scaffold

scientific article published on 26 September 2018

A photoreactive small-molecule probe for 2-oxoglutarate oxygenases

scientific article

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

scientific article published on 11 October 2019

An approach to recombinantly produce mature grape polyphenol oxidase

scientific article published on 05 July 2019

An improved method for the heterologous production of soluble human ribosomal proteins in Escherichia coli.

scientific article published on 20 June 2019

An investigation into the effect of ribosomal protein S15 phosphorylation on its intermolecular interactions by using phosphomimetic mutant

scientific article published on 25 June 2020

Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase

article

Cyclization of Linear Tetrapeptides Containing N -Methylated Amino Acids by using 1-Propanephosphonic Acid Anhydride

scientific article published on 5 December 2016

Development of NMR and thermal shift assays for the evaluation of isocitrate lyase inhibitors

scientific article published in November 2017

Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation

scholarly article by Hannah Lingard et al published 19 February 2014 in Angewandte Chemie International Edition

Dynamic combinatorial chemistry employing boronic acids/boronate esters leads to potent oxygenase inhibitors.

scientific article

Effect of consecutive rare codons on the recombinant production of human proteins in Escherichia coli

scientific article published on 11 September 2019

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

scientific article published on February 2014

Harnessing ester bond chemistry for protein ligation.

scientific article published on 13 January 2017

Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation

scientific article

Identification of Isoform-Selective Ligands for the Middle Domain of Heat Shock Protein 90 (Hsp90)

scientific article published on 26 October 2019

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen

scientific article

MCR-1: a promising target for structure-based design of inhibitors to tackle polymyxin resistance

scientific article published on 20 July 2018

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

scientific article published on 11 September 2017

NMR studies of the non-haem Fe(II) and 2-oxoglutarate-dependent oxygenases.

scientific article published on 4 September 2017

New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors

scientific article published on 15 October 2019

Non-competitive cyclic peptides for targeting enzyme-substrate complexes.

scientific article published on 23 April 2018

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

scientific article

Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments

scientific article published on 01 January 2019

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

scientific article

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

scientific article

Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy

scientific article published on 23 December 2019

Protein-Directed Dynamic Combinatorial Chemistry: A Guide to Protein Ligand and Inhibitor Discovery

scientific article

Protein-Small Molecule Interactions by WaterLOGSY

scientific article published on 20 September 2018

Protein-ligand binding affinity determination by the waterLOGSY method: An optimised approach considering ligand rebinding.

scientific article published on 3 March 2017

Selective recognition of the di/trimethylammonium motif by an artificial carboxycalixarene receptor

scientific article published on 16 January 2017

Sensory, Microbiological and Physicochemical Characterisation of Functional Manuka Honey Yogurts Containing Probiotic Lactobacillus reuteri DPC16

scientific article published on 19 January 2020

Structural and mechanistic studies on γ-butyrobetaine hydroxylase

scientific article

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.

scientific article

Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases.

scientific article

Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

scientific article published on 16 December 2015

Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain

scientific article published on 26 September 2018

Synthesis of the Azepinobisindole Alkaloid Iheyamine A Enabled by a Cross-Mannich Reaction.

scientific article published on 5 October 2016

Targeting isocitrate lyase for the treatment of latent tuberculosis.

scientific article published on 27 April 2017

Targeting mRNA translation in Parkinson's disease

scientific article published on 08 April 2019

The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

scientific article

Total Synthesis and Conformational Study of Callyaerin A: Anti-Tubercular Cyclic Peptide Bearing a Rare Rigidifying (Z)-2,3- Diaminoacrylamide Moiety

scientific article published on 18 January 2018

Total synthesis of the proposed structure of talarolide A

scientific article published in 2018

Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs

scientific article published on 23 June 2021

Virtual screening and biophysical studies lead to HSP90 inhibitors.

scientific article published on 23 November 2016

γ-Butyrobetaine hydroxylase catalyses a Stevens type rearrangement

scientific article

Paulina is supported by:

About Paulina

Help