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List of works by John D Wade

1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy

scientific article published on 01 June 1999

2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin

scientific article published on 24 June 2014

<i>De Novo</i> Design of Flavonoid-Based Mimetics of Cationic Antimicrobial Peptides: Discovery, Development, and Applications

scientific article published on 21 December 2020

A One-Pot Chemically Cleavable Bis-Linker Tether Strategy for the Synthesis of Heterodimeric Peptides

scientific article published on 16 August 2016

A Structural Core Within Apolipoprotein C-II Amyloid Fibrils Identified Using Hydrogen Exchange and Proteolysis

article

A peptide corresponding to the N-terminal 13 residues of T4 lysozyme forms an alpha-helix

scientific article published on 01 January 1993

A simple approach for the preparation of mature human relaxin-3.

scientific article published on 3 August 2010

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

scientific article published on 26 February 2016

Aberrant protein expression in plasma and kidney tissue during experimental obstructive nephropathy.

scientific article published on 4 August 2009

Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.

scientific article published in April 2006

Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones

scientific article (publication date: 25 November 2000)

Addition of a carboxy-terminal green fluorescent protein does not alter the binding and signaling properties of relaxin family Peptide receptor 3.

scientific article published on April 2009

Advantage of a Narrow Spectrum Host Defense (Antimicrobial) Peptide Over a Broad Spectrum Analog in Preclinical Drug Development

Alternative stabilities of a proline-rich antibacterial peptide in vitro and in vivo.

scientific article published on 15 April 2008

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase

scientific article

Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions

scientific article published on 2 October 2007

Amyloid Beta (Aβ) Peptide and Factors that Play Important Roles in Alzheimer's Disease

scientific article published on 28 February 2016

Amyloid-beta as a "difficult sequence" in solid phase peptide synthesis

scientific article published in August 2004

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

scientific article

An automated peptide and protein thiazolidine coupling chemistry for biosensor immobilization giving a unique N-terminal orientation

scientific article published on 26 September 2005

Analogs of insulin-like peptide 3 (INSL3) B-chain are LGR8 antagonists in vitro and in vivo.

scientific article published on 17 March 2006

Analysis of Abeta interactions using ProteinChip technology

scientific article published in January 2008

Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: racemization studies and water-based synthesis of histidine-containing peptides

scientific article published on 26 June 2014

Atomic Force Microscopy Reveals the Mechanobiology of Lytic Peptide Action on Bacteria

scientific article published on 26 May 2015

Broad-spectrum antimicrobial efficacy of peptide A3-APO in mouse models of multidrug-resistant wound and lung infections cannot be explained by in vitro activity against the pathogens involved

scientific article published on 24 February 2011

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide

scientific article published on 16 November 2016

C-terminus of the B-chain of relaxin-3 is important for receptor activity

scientific article

CD and NMR determination of the solution structure of a peptide corresponding to T4 lysozyme residues 38-51

scientific article published on 01 July 1995

Cardiovascular actions of human endothelin in conscious sheep.

scientific article

Cellular disulfide bond formation in bioactive peptides and proteins

scientific article

Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice.

scientific article published on 25 March 2014

Central relaxin-3 receptor (RXFP3) activation decreases anxiety- and depressive-like behaviours in the rat.

scientific article published on February 2013

Central relaxin-3 receptor (RXFP3) activation reduces elevated, but not basal, anxiety-like behaviour in C57BL/6J mice

scientific article published on 6 June 2015

Chemical synthesis and biological activity of rat INSL3.

scientific article

Chemical synthesis and biological evaluation of an antimicrobial peptide gonococcal growth inhibitor.

scientific article published on 4 May 2012

Chemical synthesis and orexigenic activity of rat/mouse relaxin-3.

scientific article

Chemically modified and conjugated antimicrobial peptides against superbugs

scientific article published in January 2021

Chemically synthesized dicarba H2 relaxin analogues retain strong RXFP1 receptor activity but show an unexpected loss of in vitro serum stability

scientific article published on 14 September 2015

Chimeric RXFP1 and RXFP2 Receptors Highlight the Similar Mechanism of Activation Utilizing Their N-Terminal Low-Density Lipoprotein Class A Modules.

scientific article

Chimeric relaxin peptides highlight the role of the A-chain in the function of H2 relaxin

scientific article published on 05 March 2012

Cholesterol and Clioquinol modulation of A beta(1-42) interaction with phospholipid bilayers and metals

scientific article published on 8 September 2007

Chromatin remodeling and modification during HIV-1 Tat-activated transcription

scientific article published on July 2003

Coatings Releasing the Relaxin Peptide Analogue B7-33 Reduce Fibrotic Encapsulation

scientific article published on 02 December 2019

Comparison of relaxin receptors in rat isolated atria and uterus by use of synthetic and native relaxin analogues.

scientific article

Conformation of a peptide corresponding to T4 lysozyme residues 59-81 by NMR and CD spectroscopy

scientific article published on 01 September 1994

Conformational analysis of LYS(11-36), a peptide derived from the beta-sheet region of T4 lysozyme, in TFE and SDS

scientific article published on 01 September 1997

Conformationally constrained single-chain peptide mimics of relaxin B-chain secondary structure

scientific article

Cooperative binding of insulin-like Peptide 3 to a dimeric relaxin family peptide receptor 2.

scientific article published on 6 December 2007

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge

scientific article

Correction to "Atomic Force Microscopy Reveals the Mechanobiology of Lytic Peptide Action on Bacteria"

scientific article published on 06 June 2016

Current challenges in peptide-based drug discovery

scientific article published on 8 August 2014

De novo design and synthesis of cyclic and linear peptides to mimic the binding cassette of human relaxin

scientific article published in April 2009

Defining the LGR8 residues involved in binding insulin-like peptide 3.

scientific article

Design and development of a peptide-based adiponectin receptor agonist for cancer treatment

scientific article

Design and development of analogues of dimers of insulin-like peptide 3 B-chain as high-affinity antagonists of the RXFP2 receptor

scientific article

Design and recombinant expression of insulin-like peptide 5 precursors and the preparation of mature human INSL5.

scientific article published on 11 April 2010

Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin-like peptide 3 (INSL3) B-chain.

scientific article published on February 2007

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3.

scientific article published on 8 March 2011

Designer antibacterial peptides kill fluoroquinolone-resistant clinical isolates

scientific article published in August 2005

Designer peptide antagonist of the leptin receptor with peripheral antineoplastic activity

scientific article published on 6 April 2013

Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling

scientific article published on 27 July 2016

Development of a pharmacologically improved peptide agonist of the leptin receptor

scientific article

Development of lanthanide-labeled human INSL3 as an alternative probe to radioactively labeled INSL3 for use in bioassays

scientific article published on April 2009

Development of second generation peptides modulating cellular adiponectin receptor responses.

scientific article

Diabetogenic action of human growth hormone. Synthesis and activity of C-terminal fragments

scientific article published on February 1, 1979

Dimeric structures of alpha-synuclein bind preferentially to lipid membranes

scientific article

Dimerization and negative cooperativity in the relaxin family peptide receptors

scientific article published in April 2009

Direct Measurement of Pore Dynamics and Leakage Induced by a Model Antimicrobial Peptide in Single Vesicles and Cells

scientific article published on 9 June 2016

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity.

scientific article

Effect of helix-promoting strategies on the biological activity of novel analogues of the B-chain of INSL3.

scientific article

Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer

scientific article published on 23 February 2011

Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist

scientific article published on 29 January 2016

Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA

scientific article (publication date: 25 October 2001)

Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker

scientific article published in January 2022

Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis

scientific article

Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production

scientific article published on 25 March 2013

General method for selective labelling of double-chain cysteine-rich peptides with a lanthanide chelate via solid-phase synthesis

scientific article published on 11 January 2011

H2 relaxin is a biased ligand relative to H3 relaxin at the relaxin family peptide receptor 3 (RXFP3).

scientific article

H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor

scientific article published on 31 January 2011

High density lipoproteins bind Aβ and apolipoprotein C-II amyloid fibrils

article

Human gene 2 relaxin chain combination and folding

scientific article

Human relaxin-2: historical perspectives and role in cancer biology

scientific article published on 02 August 2012

INSL3 as a biomarker of Leydig cell functionality

scientific article published on June 13, 2013

INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

scientific journal article

INSL3/RXFP2 signaling in testicular descent.

scientific article

Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments.

scientific article

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin

scientific article

Imaging the action of antimicrobial peptides on living bacterial cells

scientific article

Improved chemical synthesis and demonstration of the relaxin receptor binding affinity and biological activity of mouse relaxin.

scientific article published on 11 April 2007

Improved preparation of amyloid-beta peptides using DBU as Nalpha-Fmoc deprotection reagent.

scientific article

Inhibition of HIV-1 virus replication using small soluble Tat peptides

scientific article published on 14 November 2005

Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling

scientific article published in June 2005

Insulin-like peptide 5 is an orexigenic gastrointestinal hormone

scientific journal article

Insulin-relaxin family peptide signaling and receptors in mouse brain membranes and neuronal cells.

scientific article published on May 2005

Intramolecular acyl transfer in peptide and protein ligation and synthesis

scientific article

Intramuscularly administered peptide A3-APO is effective against carbapenem-resistant Acinetobacter baumannii in mouse models of systemic infections

scientific article

Killer bee molecules: antimicrobial peptides as effector molecules to target sporogonic stages of Plasmodium

scientific article

Long-time-scale interaction dynamics between a model antimicrobial peptide and giant unilamellar vesicles

scientific article published on 14 November 2013

Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation

scientific article published on 10 July 2014

Melittin peptides exhibit different activity on different cells and model membranes

scientific article published on 9 September 2014

Membrane interactions and the effect of metal ions of the amyloidogenic fragment Abeta(25-35) in comparison to Abeta(1-42).

scientific article published on 22 May 2007

Membrane interactions of proline-rich antimicrobial peptide, Chex1-Arg20, multimers

scientific article

Metal effects on the membrane interactions of amyloid-beta peptides

scientific article published on 25 January 2008

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

scientific article published on 24 January 2005

Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.

scientific article published on 8 February 2012

Minimum active structure of insulin-like peptide 5.

scientific article published on 21 November 2013

Modulation of hippocampal theta oscillations and spatial memory by relaxin-3 neurons of the nucleus incertus.

scientific article published on 30 October 2009

Multimerization of a Proline-Rich Antimicrobial Peptide, Chex-Arg20, Alters Its Mechanism of Interaction with the Escherichia coli Membrane

scientific article published on September 2015

Native Chemical Ligation to Minimize Aspartimide Formation during Chemical Synthesis of Small LDLa Protein

scientific article published on 27 November 2015

Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1

scientific article published on 03 August 2008

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

scientific article

Novel Methods for the Chemical Synthesis of Insulin Superfamily Peptides and of Analogues Containing Disulfide Isosteres

scientific article published on 22 August 2017

Novel strategy for the synthesis of template-assembled analogues of rat relaxin

scientific article published on 01 May 2000

Optimization of adiponectin-derived peptides for inhibition of cancer cell growth and signaling

scientific article

Peptide Multimerization as Leads for Therapeutic Development

scientific article published on 30 December 2021

Peptide-based leptin receptor antagonists for cancer treatment and appetite regulation

scientific article published on January 2011

Polyvinyl alcohol nanofiber formulation of the designer antimicrobial peptide APO sterilizes Acinetobacter baumannii-infected skin wounds in mice.

scientific article published on 29 August 2015

Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections

scientific article

Primate relaxin: synthesis of gorilla and rhesus monkey relaxins

scientific article published on 01 April 1994

Prior antibacterial peptide-mediated inhibition of protein folding in bacteria mutes resistance enzymes

scientific article published on September 2006

Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.

scientific article

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

scientific article

R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization.

scientific article published on 2 July 2007

RXFP1 couples to the Galpha-Gbetagamma-PI3K-PKCzeta pathway via the final 10 amino acids of the receptor C-terminal tail.

scientific article published on April 2009

Rapid Photolysis-Mediated Folding of Disulfide-Rich Peptides

scientific article published on 22 May 2019

Rapid systemic and local treatments with the antibacterial peptide dimer A3-APO and its monomeric metabolite eliminate bacteria and reduce inflammation in intradermal lesions infected with Propionibacterium acnes and meticillin-resistant Staphylococ

scientific article published on 07 September 2013

Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3.

scientific article published on 10 August 2009

Relaxin

scientific article published on 01 January 1997

Relaxin family peptide receptor (RXFP1) coupling to G(alpha)i3 involves the C-terminal Arg752 and localization within membrane Raft Microdomains.

scientific article

Relaxin family peptides and receptors in mammalian brain.

scientific article published on April 2009

Relaxin family peptides: structure-activity relationship studies.

scientific article published on 6 December 2016

Relaxin research in the postgenomic era.

scientific article

Relaxin-3 innervation of the intergeniculate leaflet of the rat thalamus - neuronal tract-tracing and in vitro electrophysiological studies

scientific article

Relaxin-3/RXFP3 system regulates alcohol-seeking

scientific article

Relaxin-3: Improved Synthesis Strategy and Demonstration of Its High-Affinity Interaction with the Relaxin Receptor LGR7 BothIn VitroandIn Vivo†

article

Relaxin-like bioactivity of ovine Insulin 3 (INSL3) analogues

scientific article published on December 2002

Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2.

scientific article published on 4 June 2010

Roles of the receptor, the ligand, and the cell in the signal transduction pathways utilized by the relaxin family peptide receptors 1-3.

scientific article published on April 2009

Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics

scientific article

Sequential formation of regioselective disulfide bonds in synthetic peptides with multiple disulfide bonds

scientific article published in January 2013

Short Stature Associated with a Novel Heterozygous Mutation in theInsulin-Like Growth Factor 1Gene

scientific article published on July 28, 2010

Signalling profiles of H3 relaxin, H2 relaxin and R3(BΔ23-27)R/I5 acting at the relaxin family peptide receptor 3 (RXFP3)

scientific article

Site of fluorescent label modifies interaction of melittin with live cells and model membranes

scientific article published on 4 June 2015

Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies

scientific article published on 21 December 2011

Site-specific conjugation of a lanthanide chelator and its effects on the chemical synthesis and receptor binding affinity of human relaxin-2 hormone

scientific article published on 07 March 2012

Slow insertion kinetics during interaction of a model antimicrobial peptide with unilamellar phospholipid vesicles

scientific article published on 22 December 2011

Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity

scientific article published on 24 February 2009

Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs

scientific article published on 17 October 2017

Solid-phase synthesis of europium-labeled human INSL3 as a novel probe for the study of ligand-receptor interactions

scientific article

Solid-phase synthesis of ovine Leydig cell insulin-like peptide--a putative ovine relaxin?

scientific article published on 01 May 1999

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.

scientific article

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3.

scientific article

Solution structure, aggregation behavior, and flexibility of human relaxin-2

scientific article

Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor

scientific article published on 17 November 2003

Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity

scientific article published on 25 March 2009

Structural and biosensor analyses of a synthetic biotinylated peptide probe for the isolation of adenomatous polyposis coli tumor suppressor protein complexes.

scientific article

Structural dynamics of a lytic peptide interacting with a supported lipid bilayer

scientific article published on March 2011

Structural insights into the function of relaxins

scientific article

Structural properties of relaxin chimeras.

scientific article

Structural requirements for the interaction of sheep insulin-like factor 3 with relaxin receptors in rat atria

scientific article published in December 2002

Structure and activity in the relaxin family of peptides

scientific article published in April 2009

Structure and function relationship of murine insulin-like peptide 5 (INSL5): free C-terminus is essential for RXFP4 receptor binding and activation

scientific article published on 08 September 2011

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework

scientific article

Structure of the R3/I5 Chimeric Relaxin Peptide, a Selective GPCR135 and GPCR142 Agonist

scientific article

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

scientific article published in Nature Communications

Studies on soluble ectodomain proteins of relaxin (LGR7) and insulin 3 (LGR8) receptors.

scientific article published on May 2005

Synergy between a lead proline-rich antibacterial peptide derivative and small molecule antibiotics.

scientific article

Synthesis and secondary structural studies of penta(acetyl-Hmb)A beta(1-40).

scientific article

Synthesis of a disulfide-linked octameric peptide construct carrying three different antigenic determinants.

scientific article published in June 2001

Synthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization

scientific article

Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5).

scientific article

Synthesis, conformation, receptor binding and biological activities of monobiotinylated human insulin-like peptide 3.

scientific article published in February 2004

Synthesis, conformational analysis and biological properties of a dicarba derivative of the antimicrobial peptide, brevinin-1BYa

scientific article published on 11 February 2011

Synthesis, conformational studies and biological activity of N(alpha)-mono-biotinylated rat relaxin.

scientific article

Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability.

scientific article

Synthetic human insulin 4 does not activate the G-protein-coupled receptors LGR7 or LGR8.

scientific article published on May 2004

Synthetic relaxins

scientific article published on October 2014

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors

scientific article published on 22 April 2008

The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

scientific article published on 11 December 2015

The Effect of Selective D- or Nα-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20.

scientific article published on 19 January 2017

The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured

scientific article published on 26 August 2016

The Roles of the A- and B-Chains of Human Relaxin-2 and -3 on Their Biological Activity

scientific article published on December 1, 2010

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

scientific journal article

The antibacterial effect of a proline-rich antibacterial peptide A3-APO.

scientific article published on January 2009

The chemical synthesis of relaxin and related peptides

scientific article published on 01 April 2009

The chemically synthesized human relaxin-2 analog, B-R13/17K H2, is an RXFP1 antagonist

scientific article

The chemistry and biology of human relaxin-3.

scientific article

The conformation of porcine-brain natriuretic peptide by two-dimensional NMR spectroscopy

scientific article published in October 1991

The designer leptin antagonist peptide Allo-aca compensates for short serum half-life with very tight binding to the receptor

scientific article published on 24 December 2013

The designer proline-rich antibacterial peptide A3-APO is effective against systemic Escherichia coli infections in different mouse models

scientific article published on 23 December 2009

The designer proline-rich antibacterial peptide A3-APO prevents Bacillus anthracis mortality by deactivating bacterial toxins

scientific article published on April 2014

The effects of post-translational side-chain modifications on the stimulatory activity, serum stability and conformation of synthetic peptides carrying T helper cell epitopes

scientific article published on 01 August 1996

The human insulin superfamily of polypeptide hormones

scientific article published in January 2009

The minimal active structure of human relaxin-2

scientific article

The relaxin peptide family--structure, function and clinical applications

scientific article published on March 2011

The role of Abeta peptides in Alzheimer's disease

scientific article

The severe short stature in two siblings with a heterozygous IGF1 mutation is not caused by a dominant negative effect of the putative truncated protein.

scientific article published on 14 January 2011

The structural and functional role of the B-chain C-terminal arginine in the relaxin-3 peptide antagonist, R3(BDelta23-27)R/I5.

scientific article published in January 2009

The structural determinants of insulin-like Peptide 3 activity

scientific article

The synthesis and hyperglycaemic activity of the amino acid sequence 172-191 of human growth hormone

scientific article published on 01 September 1977

The use of coiled-coil interactions for the analysis and micropreparative isolation of adenomatous polyposis coli protein complexes.

scientific article

Total Chemical Synthesis of a Nonfibrillating Human Glycoinsulin

scientific article published on 09 January 2020

Total Chemical Synthesis of an Intra-A-Chain Cystathionine Human Insulin Analogue with Enhanced Thermal Stability

scientific article published on 20 October 2016

Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2).

scientific article published on 12 December 2016

Total chemical synthesis of a heterodimeric interchain bis-lactam-linked Peptide: application to an analogue of human insulin-like Peptide 3.

scientific article published on 28 October 2013

Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis

scientific article published in August 2011

Use of a temporary "solubilizing" peptide tag for the Fmoc solid-phase synthesis of human insulin glargine via use of regioselective disulfide bond formation.

scientific article published in July 2009

Vasopressin secretion: osmotic and hormonal regulation by the lamina terminalis.

scientific article published on April 2004

Water drinking in rats resulting from intravenous relaxin and its modification by other dipsogenic factors

scientific article published on 01 November 1999