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List of works by Pancras C.W. Hogendoorn

A balanced t(5;17) (p15;q22-23) in chondroblastoma: frequency of the re-arrangement and analysis of the candidate genes.

scientific article

A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma.

scientific article

A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient

scientific article published on February 2004

A nation-wide study comparing sporadic and familial adenomatous polyposis-related desmoid-type fibromatoses.

scientific article

A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup

scientific article published on 16 March 2019

A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma Al

scientific article

A phase II study of cisplatin, ifosfamide and doxorubicin in operable primary, axial skeletal and metastatic osteosarcoma. European Osteosarcoma Intergroup (EOI).

scientific article

A phase II study of gefitinib for patients with advanced HER-1 expressing synovial sarcoma refractory to doxorubicin-containing regimens

scientific article published in April 2008

A reappraisal of hemangiopericytoma of bone; analysis of cases reclassified as synovial sarcoma and solitary fibrous tumor of bone

scientific article

A short-term in vivo model for giant cell tumor of bone.

scientific article

A translocation t(6;14) in two cases of leiomyosarcoma: Molecular cytogenetic and array-based comparative genomic hybridization characterization.

scientific article

A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures.

scientific article published on 8 July 2011

Aberrant chemokine receptor expression and chemokine production by Langerhans cells underlies the pathogenesis of Langerhans cell histiocytosis.

scientific article published on 12 May 2003

Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial

scientific article

Adamantinoma of the Long Bones: Keratin Subclass Immunoreactivity Pattern with Reference to Its Histogenesis ⬇️

scientific article published on December 1, 1993

Adamantinoma-like Ewing's sarcoma and Ewing's-like adamantinoma. The t(11; 22), t(21; 22) status

scientific article published on 01 September 2001

Adjuvant Zoledronic Acid in High-Risk Giant Cell Tumor of Bone: A Multicenter Randomized Phase II Trial

scientific article published on 30 April 2019

Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.

scientific article

Aggressive angiomyxoma: a clinicopathological and immunohistochemical study of 11 cases with long-term follow-up

scientific article published on 03 November 2004

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

scientific article

Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma

scientific article published on 01 December 2002

An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration.

scientific article published on 19 March 2012

An update of diagnostic strategies using molecular genetic and magnetic resonance imaging techniques for musculoskeletal tumors.

scientific article

Analysis of stromal cells in osteofibrous dysplasia and adamantinoma of long bones

scientific article published on 07 October 2011

Anti-EGFR Antibody Cetuximab Enhances the Cytolytic Activity of Natural Killer Cells toward Osteosarcoma

scientific article published on 16 November 2011

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

scientific article published in August 2010

Array-based comparative genomic hybridisation analysis reveals recurrent chromosomal alterations in primary diffuse large B cell lymphoma of bone

article

Array-comparative genomic hybridization of central chondrosarcoma: identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations.

scientific article published on July 2006

Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens.

scientific article

Automation of Technology for Cancer Research

scientific article published on January 2016

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

scientific article

BCRP expression in schwannoma, plexiform neurofibroma and MPNST.

scientific article

Basic fibroblast growth factor and fibroblastic growth factor receptor-1 may contribute to head and neck paraganglioma development by an autocrine or paracrine mechanism

scientific article published on 01 August 2006

Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics.

scientific article published on September 2009

Bifurcation of the femur with tibial agenesis and additional anomalies

scientific article published on 01 September 2005

Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches

scientific article published on 04 June 2018

Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone.

scientific article

Brachyury and chordoma: the chondroid-chordoid dilemma resolved?

scientific article

Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 multiple osteochondromas families

scientific article

Brostallicin versus doxorubicin as first-line chemotherapy in patients with advanced or metastatic soft tissue sarcoma: an European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group randomised phase II and pharmaco

scientific article published on 8 November 2013

Brostallicin, an agent with potential activity in metastatic soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group

scientific article published on 13 November 2006

CD33+ CD14- phenotype is characteristic of multinuclear osteoclast-like cells in giant cell tumor of bone.

scientific article published in January 2009

CD99-positive undifferentiated round cell sarcoma diagnosed on fine needle aspiration cytology, later found to harbour a CIC-DUX4 translocation: a recently described entity.

scientific article published on 3 July 2013

CT-guided, COBRA-FISH-assisted diagnosis of well-differentiated liposarcoma (inflammatory subtype) of the retroperitoneum.

scientific article published in September 2007

CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients.

scientific article published on 28 September 2015

CXCR4 signaling is controlled by immobilization at the plasma membrane

scientific article published on 31 December 2015

Calcified meningioma of the skull base simulating chondrosarcoma

scientific article published on 01 December 1995

Can MRI predict the histopathological response in patients with osteosarcoma after the first cycle of chemotherapy?

scientific article published on 01 June 1995

Can conventional radiographs be used to monitor the effect of neoadjuvant chemotherapy in patients with osteogenic sarcoma?

scientific article published on 01 January 1996

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.

scientific article published on 10 June 2010

Cartilage ultrastructure in proteoglycan-deficient zebrafish mutants brings to light new candidate genes for human skeletal disorders.

scientific article published on 5 January 2011

Cathepsin K is the principal protease in giant cell tumor of bone.

scientific article

Cell cycle/apoptosis molecule expression correlates with imatinib response in patients with advanced gastrointestinal stromal tumors.

scientific article

Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix

scientific article published on 13 March 2009

Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

scientific article published on 27 June 2008

Changing concepts in the pathological basis of soft tissue and bone sarcoma treatment.

scientific article published in July 2004

Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells.

scientific article

Chondroblastic osteosarcoma: characterisation by gadolinium-enhanced MR imaging correlated with histopathology

scientific article published on 01 March 1998

Chondroid lipoma: findings on radiography and MRI (2006:7b).

scientific article

Chondroma and chondrosarcoma of the larynx

scientific article published on April 2004

Chondromyxoid fibroma resembles in vitro chondrogenesis, but differs in expression of signalling molecules

scientific article published on 01 June 2005

Chondrosarcoma is not characterized by detectable telomerase activity

scientific article published on 01 March 2001

Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes

scientific article published on 01 December 2001

Classification of histopathologic changes following chemotherapy in Ewing's sarcoma of bone

scientific article published on 01 October 1994

Clear cell sarcoma of the stomach

scientific article published on 01 December 2002

Clinico-histologic parameters of osteosarcoma patients with late relapse

scientific article published on 19 January 2006

Co-existence of lung carcinoma metastasis and enchondroma in the femur of a patient with Ollier disease

scientific article published on 13 October 2020

Coactivated platelet-derived growth factor receptor {alpha} and epidermal growth factor receptor are potential therapeutic targets in intimal sarcoma

scientific article published on 4 August 2010

Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial. ⬇️

scientific article

Concise Review: Mesenchymal Tumors: When Stem Cells Go Mad ⬇️

scientific article published on March 1, 2011

Conjunctival Leiomyosarcoma, a Rare Neoplasm Always Originating at the Limbus? Report of a New Case and Review of 11 Published Cases

scientific article published on 24 January 2019

Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO.

scientific article

Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours

scientific article published on 01 April 2010

Critical illness VR rehabilitation device (X-VR-D): evaluation of the potential use for early clinical rehabilitation.

scientific article published on 12 January 2007

Cytogenetic analysis of adamantinoma of long bones: Further indications for a common histogenesis with osteofibrous dysplasia ⬇️

scientific article published on August 1, 1997

De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry.

scientific article

Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.

scientific article published in March 2007

Dedifferentiated adamantinoma with revertant mesenchymal phenotype

scientific article published on 01 December 2003

Dedifferentiated peripheral chondrosarcomas: regulation of EXT-downstream molecules and differentiation-related genes

scientific article published on 04 September 2009

Desmoplastic fibroma of bone: an immunohistochemical study including beta-catenin expression and mutational analysis for beta-catenin.

scientific article

Detection and molecular cytogenetic characterization of a novel ring chromosome in a histological variant of Ewing sarcoma

scientific article published on 01 January 2007

Detection of areas with viable remnant tumor in postchemotherapy patients with Ewing's sarcoma by dynamic contrast-enhanced MRI using pharmacokinetic modeling

scientific article published on 01 June 2000

Diagnosis and prognosis of chondrosarcoma of bone.

scientific article

Diffusion-weighted MRI in the characterization of soft-tissue tumors

scientific article published on 01 March 2002

Distinct histological features characterize primary angiosarcoma of bone

scientific article published on 01 January 2011

Distribution and prognostic value of histopathologic data and immunohistochemical markers in gastrointestinal stromal tumours (GISTs): An analysis of the EORTC phase III trial of treatment of metastatic GISTs with imatinib mesylate

scientific article

Distribution of extracellular matrix components in adamantinoma of long bones suggests fibrous-to-epithelial transformation.

scientific article published in February 1997

Does parosteal liposarcoma differ from other atypical lipomatous tumors/well-differentiated liposarcomas? A molecular cytogenetic study using combined multicolor COBRA-FISH karyotyping and array-based comparative genomic hybridization

scientific article published on 01 July 2007

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.

scientific article

Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study

scientific article published on 01 January 2005

Doxorubicin-based adjuvant chemotherapy in soft tissue sarcoma: pooled analysis of two STBSG-EORTC phase III clinical trials.

scientific article published on 6 October 2014

Dynamic contrast-enhanced MR imaging in monitoring response to isolated limb perfusion in high-grade soft tissue sarcoma: initial results

scientific article published on 08 January 2003

ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review

scientific article published on 08 December 2016

EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment

scientific article

EWSR1-CREB1 and EWSR1-ATF1 Fusion Genes in Angiomatoid Fibrous Histiocytoma

article

EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.

scientific article

Enchondromatosis (Ollier disease, Maffucci syndrome) is not caused by the PTHR1 mutation p.R150C.

scientific article

Epiphyseal growth plate and secondary peripheral chondrosarcoma: the neighbours matter.

scientific article

Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53.

scientific article

Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway.

scientific article

Expression of CCL21 in Ewing sarcoma shows an inverse correlation with metastases and is a candidate target for immunotherapy.

scientific article published on July 2016

Expression of ERG, an Ets family transcription factor, identifies ERG-rearranged Ewing sarcoma.

scientific article

Expression of cell cycle-related gene products in Langerhans cell histiocytosis.

scientific article published in December 2002

Expression of cellular FLICE inhibitory protein, caspase-8, and protease inhibitor-9 in Ewing sarcoma and implications for susceptibility to cytotoxic pathways.

scientific article published on January 2007

Expression of growth factors and their receptors in adamantinoma of long bones and the implication for its histogenesis

scientific article published on 01 January 1998

Extra-abdominal subcutaneous metastasis of a gastrointestinal stromal tumor: report of a case and a review of the literature.

scientific article published on 06 October 2008

Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice

scientific article published on 25 April 2013

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

scientific article

Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype

scientific article published on 01 October 2021

Frequent truncating mutations of STAG2 in bladder cancer

scientific article published on 13 October 2013

G2M arrest, blocked apoptosis, and low growth fraction may explain indolent behavior of head and neck paragangliomas.

scientific article published in July 2003

GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.

scientific article

Gemcitabine in advanced adult soft-tissue sarcomas. A phase II study of the EORTC Soft Tissue and Bone Sarcoma Group.

scientific article published in March 2002

Gene expression profiling of giant cell tumor of bone reveals downregulation of extracellular matrix components decorin and lumican associated with lung metastasis.

scientific article published on 11 October 2014

Genome-wide analyses on high-grade osteosarcoma: making sense of a genomically most unstable tumor.

scientific article published on 16 March 2013

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours

scientific article

Genomic instability in giant cell tumor of bone. A study of 52 cases using DNA ploidy, relocalization FISH, and array-CGH analysis.

scientific article published in June 2009

Genomic profiling of chondrosarcoma: chromosomal patterns in central and peripheral tumors.

scientific article published on 31 March 2009

Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos

scientific article published on 28 August 2019

Growth plate regulation and osteochondroma formation: insights from tracing proteoglycans in zebrafish models and human cartilage.

scientific article published on 19 April 2011

HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas

scientific article

Hematopoietic Tumors Primarily Presenting in Bone

scientific article published on 27 June 2017

Heterogeneous and complex rearrangements of chromosome arm 6q in chondromyxoid fibroma: delineation of breakpoints and analysis of candidate target genes

scientific article published on 9 August 2010

Hierarchical clustering of flow cytometry data for the study of conventional central chondrosarcoma.

scientific article

High frequency ofMYCgene amplification is a common feature of radiation-induced sarcomas. Further results from EORTC STBSG TL 01/01

scientific article published on 25 September 2012

High prevalence of autoimmune disease in the rare inflammatory bone disorder sternocostoclavicular hyperostosis: survey of a Dutch cohort.

scientific article published on 25 January 2017

How is the mutational status for tumor suppressors p53 and p16(INK4A) in MFH of the bone?

scientific article published on 01 January 1998

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

scientific article

IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis

scientific article

IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

scientific article

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

scientific article

Identification of an EWS-pseudogene using translocation detection by RT-PCR in Ewing's sarcoma.

scientific article

Identification of markers to characterize and sort human articular chondrocytes with enhanced in vitro chondrogenic capacity.

scientific article

Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data.

scientific article

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

scientific article

Imaging mass spectrometry-based molecular histology differentiates microscopically identical and heterogeneous tumors

scientific article

Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sa

scientific article

Imatinib mesylate in patients with WHO B3 thymomas and thymic carcinomas.

scientific article published in October 2009

Improved diagnosis and treatment of soft tissue sarcoma patients after implementation of national guidelines: a population-based study.

scientific article published on 13 June 2009

Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma Intergroup.

scientific article

In reply

Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.

scientific article

Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.

scientific article published on 12 October 2015

Inactive Wnt/beta-catenin pathway in conventional high-grade osteosarcoma

scientific article published on 01 January 2010

Incidence of biopsy-proven bone tumors in children: a report based on the Dutch pathology registration "PALGA".

scientific article published in January 2008

Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients

scientific article published on 6 December 2011

Increased HIF1α in SDH and FH deficient tumors does not cause microsatellite instability

Increased dynamin expression precedes proteinuria in glomerular disease

article

Infantile-type digital fibromatosis tumour in an adult.

scientific article

Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trial

scientific article published in August 2005

Intact interferon signaling in peripheral blood leukocytes of high-grade osteosarcoma patients

scientific article

Interobserver reliability in the histopathological diagnosis of cartilaginous tumors in patients with multiple osteochondromas ⬇️

scientific article published on 04 May 2012

Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas

scientific article

Introducing fluorescence guided surgery into orthopedic oncology: A systematic review of candidate protein targets for Ewing sarcoma

scientific article published on 13 September 2018

Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy.

scientific article

Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment.

scientific article

Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option.

scientific article published on 23 September 2010

Langerhans cell histiocytosis: a pathologic combination of oncogenesis and immune dysregulation.

scientific article published in May 2004

Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage.

scientific article published on March 2010

Langerhans-cell histiocytosis 'insight into DC biology'.

scientific article

Late sarcoma development after curettage and bone grafting of benign bone tumors

article

Limited rescue of osteoclast-poor osteopetrosis after successful engraftment by cord blood from an unrelated donor

scientific article published on 08 August 2005

Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model

article

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

scientific article published on 01 September 2016

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival.

scientific article published on 18 March 2016

Low-grade chondrosarcoma of long bones treated with intralesional curettage followed by application of phenol, ethanol, and bone-grafting.

scientific article published in July 2012

Lymphatics and bone

scientific article published on 01 October 2007

Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas

scientific article published on 23 June 2009

M-CSF and IL-34 expression as indicators for growth in sporadic vestibular schwannoma.

scientific article published on 22 December 2018

MR imaging based strategies in limb salvage surgery for osteosarcoma of the distal femur

scientific article published on 01 November 1997

MR imaging characteristics in primary lymphoma of bone with emphasis on non-aggressive appearance

scientific article published on 09 June 2007

MRI appearances of atypical cartilaginous tumour/grade I chondrosarcoma after treatment by curettage, phenolisation and allografting: recommendations for follow-up

scientific article published in December 2016

Maffucci syndrome: a genome-wide analysis using high resolution single nucleotide polymorphism and expression arrays on four cases.

scientific article published on 16 May 2011

Magnetic resonance imaging of knee cartilage using a water selective balanced steady-state free precession sequence

scientific article

Malignant fibrous histiocytoma and fibrosarcoma of bone: a re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches.

scientific article published on 22 September 2012

Malignant melanoma is genetically distinct from clear cell sarcoma of tendons and aponeurosis (malignant melanoma of soft parts).

scientific article published on February 2001

Malignant progression in multiple enchondromatosis (Ollier's disease): an autopsy-based molecular genetic study

scientific article published on 01 October 2000

Mesenchymal stem cell transformation and sarcoma genesis ⬇️

scientific article published on July 23, 2013

Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture.

scientific article published on 23 June 2015

Metastasis of breast carcinoma to a primary mucinous cystadenocarcinoma of the ovary

scientific article published on 01 January 1994

Method to measure the mismatch between target and achieved received dose intensity of chemotherapy in cancer trials: a retrospective analysis of the MRC BO06 trial in osteosarcoma

scientific article published on 30 May 2019

Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good R

scientific article

Molecular cytogenetic characterization of four previously established and two newly established Ewing sarcoma cell lines.

scientific article published on April 2006

Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis

scientific article published on 01 December 1999

Molecular identification of a partial hydatidiform mole

scientific article published on 01 February 1997

Molecular pathology and its diagnostic use in bone tumors.

scientific article

Molecular pathology of sarcomas: concepts and clinical implications

scientific article

Monitoring the effect of chemotherapy in Ewing's sarcoma of bone with MR imaging

scientific article published on 01 October 1994

Multicolor fluorescence in situ hybridization analysis of a synovial sarcoma of the larynx with a t(X;18)(p11.2;q11.2) and trisomies 2 and 8.

scientific article

Multiple osteochondromas: clinicopathological and genetic spectrum and suggestions for clinical management

scientific article

Multiple statistical analysis techniques corroborate intratumor heterogeneity in imaging mass spectrometry datasets of myxofibrosarcoma

scientific article

Mutation screening of EXT1 and EXT2 by direct sequence analysis and MLPA in patients with multiple osteochondromas: splice site mutations and exonic deletions account for more than half of the mutations

scientific article published on 01 April 2005

Mutation-driven epigenetic alterations as a defining hallmark of central cartilaginous tumours, giant cell tumour of bone and chondroblastoma

scientific article published on 14 November 2019

Mutations affecting BRAF, EGFR, PIK3CA, and KRAS are not associated with sporadic vestibular schwannomas.

scientific article

Myxoid tumours of soft tissue.

scientific article

Myxoid tumours of soft tissue: the so-called myxoid extracellular matrix is heterogeneous in composition.

scientific article published in March 2008

Neoadjuvant denosumab for extensive giant cell tumor in os ischium: a case report

scientific article

New indicators and indexes for benchmarking university-industry-government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project

article

Nikolay Ivanovich Pirogov (1810-1881): A pioneering Russian surgeon and medical scientist

scientific article published on 8 March 2016

Nikolay Ivanovich Pirogov (1810-1881): Anatomical research to develop surgery

scientific article published on 03 October 2019

Nikolay Ivanovich Pirogov: a surgeon's contribution to military and civilian anaesthesia

scientific article

No genomic aberrations in Langerhans cell histiocytosis as assessed by diverse molecular technologies

scientific article published on 01 March 2009

No haploinsufficiency but loss of heterozygosity for EXT in multiple osteochondromas

scientific article

Non-ossifying fibroma: A RAS-MAPK driven benign bone neoplasm

scientific article published on 20 March 2019

Novel splice variants of CXCR4 identified by transcriptome sequencing

scientific article published on 27 August 2015

Nuclear factor-κB activation in primary lymphoma of bone ⬇️

scientific article published on January 19, 2013

Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples

scientific article

Osteosarcoma models: from cell lines to zebrafish

scientific article published on 15 March 2012

Osteosarcoma of the hands and feet: a distinct clinico-pathological subgroup.

scientific article published on 5 December 2012

Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

scientific article

Paclitaxel in patients with advanced angiosarcomas of soft tissue: a retrospective study of the EORTC soft tissue and bone sarcoma group.

scientific article

Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype.

scientific article published on 4 February 2015

Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling.

scientific article

Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation

scientific article published on 25 November 2011

Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin

scientific article

Phase III Trial of Two Investigational Schedules of Ifosfamide Compared With Standard-Dose Doxorubicin in Advanced or Metastatic Soft Tissue Sarcoma: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Stud

article

Pitfalls in pathology of soft tissue sarcomas.

scientific article published in January 2004

Podoplanin expression in adamantinoma of long bones and osteofibrous dysplasia

scientific article published on 16 April 2011

Possible effects of EXT2 on mesenchymal differentiation--lessons from the zebrafish

scientific article published in 2014

Predictive and prognostic factors associated with soft tissue sarcoma response to chemotherapy: a subgroup analysis of the European Organisation for Research and Treatment of Cancer 62012 study

scientific article

Prenatal detection of orbital rhabdomyosarcoma

scientific article published on 01 February 2005

Preoperative evaluation and monitoring chemotherapy in patients with high-grade osteogenic and Ewing's sarcoma: review of current imaging modalities.

scientific article published on February 1998

Presence of chemotherapy-induced toxicity predicts improved survival in patients with localised extremity osteosarcoma treated with doxorubicin and cisplatin: a report from the European Osteosarcoma Intergroup.

scientific article

Primary cilia organization reflects polarity in the growth plate and implies loss of polarity and mosaicism in osteochondroma

scientific article published on 26 April 2010

Primary lymphoma of bone: extranodal lymphoma with favourable survival independent of germinal centre, post-germinal centre or indeterminate phenotype

scientific article published on 01 September 2009

Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype.

scientific article published in November 2004

Pro-inflammatory chemokine-chemokine receptor interactions within the Ewing sarcoma microenvironment determine CD8(+) T-lymphocyte infiltration and affect tumour progression.

scientific article

Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways

scientific article published on 01 December 2009

Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways.

scientific article

Prognosis of Primary and Recurrent Chondrosarcoma of the Rib.

scientific article published on 23 October 2015

Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas

article by Stefan Sleijfer et al published January 2010 in European Journal of Cancer

Prognostic factors in pulmonary metastasized high-grade osteosarcoma.

scientific article published in February 2010

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

scientific article

Quality of Life of Patients With Osteosarcoma in the European American Osteosarcoma Study-1 (EURAMOS-1): Development and Implementation of a Questionnaire Substudy

scientific article published on 26 September 2019

Quantification of the heterogeneity of prognostic cellular biomarkers in ewing sarcoma using automated image and random survival forest analysis

scientific article

Re. Review article entitled 'The neoplastic pathogenesis of solitary and multiple osteochondromas'

scientific article published on 01 March 2000

Reclassification and subtyping of so-called malignant fibrous histiocytoma of bone: comparison with cytogenetic features

scientific article

Recurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway

scientific article

Results of a phase II pilot study of moderate dose radiotherapy for inoperable desmoid-type fibromatosis--an EORTC STBSG and ROG study (EORTC 62991-22998).

scientific article

Ring chromosome 4 as the sole cytogenetic anomaly in a chondroblastoma: a case report and review of the literature.

scientific article

Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study

scientific article

Running GAGs: myxoid matrix in tumor pathology revisited: what's in it for the pathologist?

scientific article

SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology.

scientific article published in November 2003

Sclerostin in Mineralized Matrices and van Buchem Disease

scientific article published on 01 June 2009

Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

scientific article

Sdhd and SDHD/H19 knockout mice do not develop paraganglioma or pheochromocytoma

scientific article

Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes

scientific article

Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis

scientific article

Small deletions but not methylation underlie CDKN2A/p16 loss of expression in conventional osteosarcoma.

scientific article

Soft tissue sarcomas: introduction to the Virchows Archiv review issue.

scientific article published on 18 February 2010

Soft-tissue tumors: value of static and dynamic gadopentetate dimeglumine-enhanced MR imaging in prediction of malignancy.

scientific article published on 30 September 2004

Somatic loss of maternal chromosome 11 causes parent-of-origin-dependent inheritance in SDHD-linked paraganglioma and phaeochromocytoma families.

scientific article published in May 2004

Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation

scientific article published on 27 August 2020

Superior performance of liquid-based versus conventional cytology in a population-based cervical cancer screening program

scientific article published on 16 January 2009

Survival after recurrent osteosarcoma: data from 3 European Osteosarcoma Intergroup (EOI) randomized controlled trials

scientific article

Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

scientific article published on 25 January 2019

Survival from high-grade localised extremity osteosarcoma: combined results and prognostic factors from three European Osteosarcoma Intergroup randomised controlled trials.

scientific article

Synovial sarcoma: dynamic contrast-enhanced MR imaging features

scientific article published on 01 January 2001

TGF-beta1 drives partial myofibroblastic differentiation in chondromyxoid fibroma of bone.

scientific article

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology

scientific article (publication date: April 2009)

The Role of EXT1 in Nonhereditary Osteochondroma: Identification of Homozygous Deletions

article

The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma.

scientific article

The clinical approach toward giant cell tumor of bone

scientific article

The clinical approach towards chondrosarcoma

scientific article

The clinical use of biomarkers as prognostic factors in Ewing sarcoma ⬇️

scientific article published on February 8, 2012

The density of CD8+ T-cell infiltration and expression of BCL2 predicts outcome of primary diffuse large B-cell lymphoma of bone.

scientific article

The immunophenotype of osteoclasts and macrophage polykaryons

scientific article published on 11 May 2011

The incidence, mutational status, risk classification and referral pattern of gastro-intestinal stromal tumours in the Netherlands: a nationwide pathology registry (PALGA) study.

scientific article published on 8 January 2018

The management of diffuse-type giant cell tumour (pigmented villonodular synovitis) and giant cell tumour of tendon sheath (nodular tenosynovitis).

scientific article published on July 2012

The molecular and cellular basis of exostosis formation in hereditary multiple exostoses

scientific article published on 01 April 2009

The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target

scientific article

The role of noncartilage-specific molecules in differentiation of cartilaginous tumors: lessons from chondroblastoma and chondromyxoid fibroma.

scientific article

The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting

scientific article published on 03 March 2005

Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone

scientific article

Tiling resolution array-CGH shows that somatic mosaic deletion of the EXT gene is causative in EXT gene mutation negative multiple osteochondromas patients

article

Transactivating mutation of theMYOD1gene is a frequent event in adult spindle cell rhabdomyosarcoma

article

Tumor Biology of Vestibular Schwannoma: A Review of Experimental Data on the Determinants of Tumor Genesis and Growth Characteristics

scientific article

Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia.

scientific article

Tumor-associated eosinophilic infiltrate of cervical cancer is indicative for a less effective immune response

scientific article published on 01 September 1996

Tumor-associated macrophages are related to volumetric growth of vestibular schwannomas.

scientific article published in February 2013

Women in healthcare in Imperial Russia: The contribution of the surgeon Nikolay I Pirogov

scientific article published on 14 January 2019

Zebrafish as a model for human osteosarcoma

scientific article

[Malignant cartilage tumors]

scientific article published on 01 June 1998

cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade.

scientific article

mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts

scientific article

‘The chicken or the egg?’ dilemma strikes back for the controlling mechanism in chordoma# ⬇️

scientific article published on November 1, 2012

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