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List of works by Jacques De Greve

A novel triplet regimen with paclitaxel, carboplatin and gemcitabine (PACCAGE) as induction chemotherapy for locally advanced unresectable non small cell lung cancer (NSCLC).

scientific article

A phase II trial to assess efficacy and safety of afatinib in extensively pretreated patients with HER2-negative metastatic breast cancer ⬇️

scientific article published on July 5, 2012

A randomized, double-blind, phase II study of two doses of pemetrexed as first-line chemotherapy for advanced breast cancer

scientific article published on 01 June 2007

A single-blind, randomised, vehicle-controlled dose-finding study of recombinant human granulocyte colony-stimulating factor (lenograstim) in patients undergoing chemotherapy for solid cancers and lymphoma

scientific article published on 01 December 1995

About the c.156_157insAlu BRCA2 breast cancer predisposing mutation

scientific article published on 21 September 2008

Alteration of jun proto-oncogene status by plasmid transfection affects growth of human ovarian cancer cells.

scientific article published on August 1999

BRCA 1/2 gene mutation testing-based cancer prevention and the moral concerns of different types of patients

scientific article published on 01 January 1999

BRCA2 founder mutation in Slovenian breast cancer families.

scientific article

BRCA2 gene mutations in Slovenian male breast cancer patients

article

Breast cancer risk is increased in the years following false-positive breast cancer screening

scientific article

Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families

scientific article published on 01 March 2010

Catheter tip position as a risk factor for thrombosis associated with the use of subcutaneous infusion ports

scientific article published on 05 November 2004

Characterization of permanent cell lines that contain the AAV2 rep-cap genes on an Epstein-Barr-virus-based episomal plasmid

scientific article

Clinical activity of afatinib (BIBW 2992) in patients with lung adenocarcinoma with mutations in the kinase domain of HER2/neu.

scientific article

Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells.

scientific article published on 20 August 2015

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade

scientific article

Comparison of a gene expression profiling strategy to standard clinical work-up for determination of tumour origin in cancer of unknown primary (CUP).

scientific article published in August 2013

Complete metabolic tumour response, assessed by 18-fluorodeoxyglucose positron emission tomography (18FDG-PET), after induction chemotherapy predicts a favourable outcome in patients with locally advanced non-small cell lung cancer (NSCLC).

scientific article published on 3 April 2008

Contaminants within bacterial plasmid preparations trigger apoptosis in liposome transfected OVCAR3, but not in SKOV3 or AZ224 human ovarian cancer cells.

scientific article

Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver.

scientific article published in January 2004

Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab

scientific article published on 29 June 2012

Deconvolution-based dynamic contrast-enhanced MR imaging of breast tumors: correlation of tumor blood flow with human epidermal growth factor receptor 2 status and clinicopathologic findings--preliminary results.

scientific article published on 9 September 2008

Detection of EGFR-TK domain-activating mutations in NSCLC with generic PCR-based methods

scientific article

Effect of neck position during radionuclide superior cavography. Its value in the diagnosis of superior vena cava obstruction due to retrosternal goiter

scientific article published on 01 September 1983

Effect of siRNAs targeting the EGFR T790M mutation in a non-small cell lung cancer cell line resistant to EGFR tyrosine kinase inhibitors and combination with various agents.

scientific article

Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study

scientific article published on 06 August 2013

Evaluation of a comprehensive rehabilitation program for post-treatment patients with cancer.

scientific article published in November 2011

Fatal pulmonary toxicity by the association of radiotherapy and medroxyprogesterone acetate

scientific article published on 01 November 1985

Five recurrent BRCA1/2 mutations are responsible for cancer predisposition in the majority of Slovenian breast cancer families.

scientific article

Fotemustine in patients with advanced gastric cancer, a phase II trial from the EORTC-GITCCG (European Organization for Research and Treatment of Cancer, Gastrointestinal Tract Cancer Cooperative Group).

scientific article

Frequent incidence of BARD1-truncating mutations in germline DNA from triple-negative breast cancer patients

scientific article

Gefitinib monotherapy in advanced nonsmall cell lung cancer: a large Western community implementation study.

scientific article published on 27 September 2006

Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers

scientific article

Geographical distribution of Slovenian BRCA1/2 families according to family origin: implications for genetic screening

scientific article published on 11 March 2013

Hereditary breast and ovarian cancer and reproduction: an observational study on the suitability of preimplantation genetic diagnosis for both asymptomatic carriers and breast cancer survivors.

scientific article published on 19 April 2014

Hereditary breast cancer: from bench to bedside.

scientific article

High-dose 5-fluorouracil plus low dose methotrexate plus or minus low-dose PALA in advanced colorectal cancer: a randomised phase II-III trial of the EORTC Gastrointestinal Group.

scientific article

How to monitor cardiac toxicity of chemotherapy: time is muscle!

scientific article published on 17 December 2013

Imaging of renal cell cancer with radiolabelled octreotide.

scientific article

Influence of RT-qPCR primer position on EGFR interference efficacy in lung cancer cells.

scientific article

Is adjuvant treatment with vinblastine effective in reducing the occurrence of distant metastasis in limited squamous cell lung cancer? A randomized study

scientific article published on 01 January 1988

Long-term survival in an adult metastatic renal peripheral primitive neuroectodermal tumor (PPNET) with multimodality treatment including high-dose chemotherapy

scientific article published on 01 July 1997

Loss of nuclear BRCA1 localization in breast carcinoma is age dependent

scientific article published on 04 December 2001

Loss of nuclear BRCA1 protein staining in normal tissue cells derived from BRCA1 and BRCA2 mutation carriers

scientific article published on 12 March 2007

Lower motor neuron disease in a patient with Hodgkin's disease treated with radiotherapy

scientific article published on 01 January 1984

MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma.

scientific article published on 20 October 2008

Metastatic adenocarcinoma of the lung in a 27-year-old pregnant woman

scientific article published on 01 May 2007

Multicenter phase II randomized trial evaluating antiangiogenic therapy with sunitinib as consolidation after objective response to taxane chemotherapy in women with HER2-negative metastatic breast cancer.

scientific article published on 22 July 2010

Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Res

scientific article

Non-small-cell lung cancer with multiple paraneoplastic syndromes

scientific article published on 01 July 1995

Nutrition therapy in cachectic cancer patients. The Tight Caloric Control (TiCaCo) pilot trial

scientific article published on 22 April 2015

Olaparib tablet formulation: effect of food on the pharmacokinetics after oral dosing in patients with advanced solid tumours.

scientific article published on 5 August 2015

Osteopathia striata with cranial sclerosis. Report of a case and review of the literature

scientific article published on January 1983

Paraneoplastic syndromes in cancer: Case 1. Polycythemia as a result of ectopic erythropoietin production in metastatic pancreatic carcinoid tumor.

scientific article published in June 2004

Performance of two geriatric screening tools in older patients with cancer.

scientific article published on 25 November 2013

Phase II study of afatinib, an irreversible ErbB family blocker, in demographically and genotypically defined lung adenocarcinoma.

scientific article published on 23 January 2015

Phase II study of preoperative helical tomotherapy for rectal cancer.

scientific article published on 27 September 2007

Phase II study of sorafenib in patients with advanced hepatocellular carcinoma

scientific article published on 14 August 2006

Phase II study of sunitinib malate in patients with recurrent high-grade glioma.

scientific article

Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer

scientific article published on 5 May 2014

Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

scientific article published on 20 April 2010

Quantifying independent risk factors for failing to rescreen in a breast cancer screening program in Flanders, Belgium.

scientific article published on 20 October 2014

Restoration of an impaired TGF-beta1 autocrine growth-inhibitory circuit results in growth inhibition of ovarian epithelial cancer cells and complete inhibition of their tumorigenicity

scientific article published in January 2003

Savene® (dexrazoxane) use in clinical practice ⬇️

scientific article published on January 27, 2012

Specific congenital malformations after exposure to cyclophosphamide, epirubicin and 5-fluorouracil during the first trimester of pregnancy

scientific article published on 14 December 2010

Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma.

scientific article published on 2 June 2009

Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib

scientific article

Targeting USP13 mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in Non-Small Cell Lung Cancer

scientific article published on 19 November 2020

Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab.

scientific article

The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers.

scientific article

The influence of clinical assessment (including age) and geriatric assessment on treatment decisions in older patients with cancer

scientific article published on 23 May 2013

The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population

scientific article

The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics.

scientific article

The relationship between vagal nerve activity and clinical outcomes in prostate and non-small cell lung cancer patients.

scientific article published on 9 September 2013

Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

scientific article published on 01 January 1999

Tumour stimulating effects of recombinant human interleukin-6

scientific article published on 01 December 1994

miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells

scientific article

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