Search filters

List of works by Karla Plevová

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

scientific article published on 16 June 2016

Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference

scientific article published on 21 April 2016

Analysis of prognostic significance of merkel cell polyomavirus in chronic lymphocytic leukemia

scientific article published on 11 February 2015

Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia

scientific article

Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants.

scientific article published on 12 June 2019

C-terminal RUNX1 mutation in familial platelet disorder with predisposition to myeloid malignancies

scientific article published on 06 August 2018

CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase

scientific article published on 12 September 2018

COBLL1, LPL and ZAP70 expression defines prognostic subgroups of chronic lymphocytic leukemia patients with high accuracy and correlates with IGHV mutational status.

scientific article

Casein Kinase 1 is a Therapeutic Target in Chronic Lymphocytic Leukemia.

scientific article published on 9 January 2018

Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data

scientific article

Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients.

scientific article

Chromosome banding analysis of peripheral blood lymphocytes stimulated with IL2 and CpG oligonucleotide DSP30 in patients with chronic lymphocytic leukemia

scientific article published in January 2013

Chromothripsis - Extensive Chromosomal Rearrangements and Their Significance in Cancer

scientific article published on 01 January 2019

Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

scientific article published on 23 May 2017

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

scientific article

Clinical impact of genomic analysis in children with B-acute lymphoblastic leukemia: A pilot study in Slovakia

scientific article published on 04 August 2019

Clonal evolution in chronic lymphocytic leukemia detected by fluorescence in situ hybridization and conventional cytogenetics after stimulation with CpG oligonucleotides and interleukin-2: a prospective analysis.

scientific article published on 29 October 2013

Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact

scientific article published on 02 January 2019

DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy

scientific article published on 02 December 2019

Decreased WNT3 expression in chronic lymphocytic leukaemia is a hallmark of disease progression and identifies patients with worse prognosis in the subgroup with mutated IGHV.

scientific article published on 21 September 2016

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

scientific article published on 19 May 2016

Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2.

scientific article

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.

scientific article published on 28 November 2016

Encyclopedia of CLL Subsets - a Unique Bioinformatics Tool and Database for Analysis of Subsets of Stereotypical B-Cell Receptors in CLL

scientific article published on 01 January 2019

Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression

scientific article published on 06 April 2016

Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia

scientific article published on 9 November 2017

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia

scientific article published on 18 May 2015

Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study

scientific article published on 23 January 2020

High-quality full-length immunoglobulin profiling with unique molecular barcoding.

scientific article

Identification of Clinically Relevant Subgroups of Chronic Lymphocytic Leukemia Through Discovery of Abnormal Molecular Pathways

scientific article published on 28 June 2021

Identification of novel sequence variations in microRNAs in chronic lymphocytic leukemia

scientific article

Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia

scientific article published on 15 January 2019

Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status

scientific article published on 24 July 2017

MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia

scientific article

Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL.

scientific article published on 29 August 2017

Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

scientific article published on 13 September 2013

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy

scientific article published on 21 December 2017

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

scientific article

Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study

scientific article published on April 2015

Post-translational modifications regulate signalling by Ror1.

scientific article published on 27 May 2011

Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS

scientific article published on 21 June 2019

ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells

scientific article

Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients

scientific article published on 29 July 2016

Specific p53 mutations do not impact results of alemtuzumab therapy among patients with chronic lymphocytic leukemia

scientific article published on 01 March 2012

TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods.

scientific article published on 20 December 2014

Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia

scientific article published on 27 September 2018

Telomere dynamics in adult hematological malignancies

scientific article published on 10 January 2019

The frequency ofTP53gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors

article

The importance of complex karyotype in prognostication and treatment of chronic lymphocytic leukemia (CLL): a comprehensive review of the literature

scientific article published on 18 February 2019

The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration.

scientific article

Towards error-free profiling of immune repertoires.

scientific article published on 04 May 2014

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

scientific article published on 16 December 2015